Frontiers in Psychiatry,
Journal Year:
2023,
Volume and Issue:
14
Published: April 17, 2023
Childhood
trauma
(CT)
is
a
known
risk
factor
for
major
depressive
disorder
(MDD),
but
the
mechanisms
linking
CT
and
MDD
remain
unknown.
The
purpose
of
this
study
was
to
examine
influence
depression
diagnosis
on
subregions
anterior
cingulate
cortex
(ACC)
in
patients.The
functional
connectivity
(FC)
ACC
evaluated
60
first-episode,
drug-naïve
patients
(40
with
moderate-to-severe
20
no
or
low
CT),
78
healthy
controls
(HC)
(19
59
CT).
correlations
between
anomalous
FC
severity
symptoms
were
investigated.Individuals
moderate-to
severe
exhibited
increased
caudal
middle
frontal
gyrus
(MFG)
than
individuals
CT,
regardless
diagnosis.
showed
lower
dorsal
superior
(SFG)
MFG.
They
also
subgenual/perigenual
temporal
(MTG)
angular
(ANG)
HCs,
severity.
left
MFG
mediated
correlation
Trauma
Questionnaire
(CTQ)
total
score
HAMD-cognitive
patients.Functional
changes
MDD.
These
findings
contribute
our
understanding
neuroimaging
BMC Nursing,
Journal Year:
2023,
Volume and Issue:
22(1)
Published: Nov. 15, 2023
Abstract
Background
Nurses
bear
a
lot
of
stressors
at
work.
The
10-item
Perceived
Stress
Scale
(PSS-10)
is
widely
used
self-reported
scale
for
measuring
the
global
perception
stress.
However,
there
lack
use
PSS-10
in
Chinese
nurses.
This
study
aimed
to
test
psychometric
properties
among
Methods
A
total
708
nurses
completed
PSS-10,
Big
Five
Inventory
(BFI),
and
Depression
Anxiety
(DASS).
Confirmatory
factor
analysis
(CFA)
tested
structure
PSS-10.
Cronbach’s
α
test-retest
correlation
examined
reliability.
Pearson
hierarchical
regression
analyses
convergent,
discriminant
criterion
validity
Results
CFA
revealed
that
two-factor
model
fits
(
χ
2
/
df
=
6.25,
p
<
0.001;
comparative
fit
index
[CFI]
0.94,
non-normal
[NNFI]
0.92,
Tucker-Lewis
[TLI]
0.91,
root
mean
square
error
approximation
[RMSEA]
0.08,
standardized
residual
[SRMR]
0.05).
demonstrated
adequate
internal
consistency
(α
0.86)
reliability
r
0.66,
0.001),
satisfactory
convergent
with
relations
personalities,
as
well
good
such
score
could
explain
incremental
variance
predicting
anxiety,
depression
Conclusions
Our
findings
suggest
reliable
valid
measure
perceived
stress
can
be
future
research
practice
on
management
coping
Oxford University Press eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 371 - 430
Published: May 7, 2024
Abstract
‘Anxiety
and
personality’
links
the
anxiolytic-derived
state
neuropsychology
of
previous
chapters
to
personality
traits.
Traits
are
seen
as
sensitivities
structures,
goal
control
systems,
more
global
modulators
systems.
It
lays
ground
work
for
seeing
psychiatric
disorders
resulting
from
one
or
extreme
sensitivities.
While
main
focus
is
anxiety,
it
also
discusses
implications
Reinforcement
Sensitivity
Theory
(RST)
with
additional
comment
on
Big
5.
reviews
issues
arising
word
meanings,
evolution,
need
biomarkers,
hierarchical
organization,
continuity
versus
discontinuity
provides
recommendation
application
work,
throughout.
distinguishes
neuroticism
trait
a
new
dopaminergic
neurology
reinforcement
sensitivity,
strongly
reinforcers,
first
anxiety
disorder
biomarker,
identifies
problems
existing
RST
scales,
future
neural
solutions.
Frontiers in Psychiatry,
Journal Year:
2023,
Volume and Issue:
14
Published: April 17, 2023
Childhood
trauma
(CT)
is
a
known
risk
factor
for
major
depressive
disorder
(MDD),
but
the
mechanisms
linking
CT
and
MDD
remain
unknown.
The
purpose
of
this
study
was
to
examine
influence
depression
diagnosis
on
subregions
anterior
cingulate
cortex
(ACC)
in
patients.The
functional
connectivity
(FC)
ACC
evaluated
60
first-episode,
drug-naïve
patients
(40
with
moderate-to-severe
20
no
or
low
CT),
78
healthy
controls
(HC)
(19
59
CT).
correlations
between
anomalous
FC
severity
symptoms
were
investigated.Individuals
moderate-to
severe
exhibited
increased
caudal
middle
frontal
gyrus
(MFG)
than
individuals
CT,
regardless
diagnosis.
showed
lower
dorsal
superior
(SFG)
MFG.
They
also
subgenual/perigenual
temporal
(MTG)
angular
(ANG)
HCs,
severity.
left
MFG
mediated
correlation
Trauma
Questionnaire
(CTQ)
total
score
HAMD-cognitive
patients.Functional
changes
MDD.
These
findings
contribute
our
understanding
neuroimaging