Comprehensive Psychoneuroendocrinology, Journal Year: 2024, Volume and Issue: 20, P. 100272 - 100272
Published: Oct. 24, 2024
Language: Английский
Communications Psychology, Journal Year: 2025, Volume and Issue: 3(1)
Published: April 13, 2025
Altered states of consciousness (ASCs), induced e.g. during psychedelic-assisted therapy, show potential to treat prevalent mental health disorders like depression and posttraumatic stress disorder. However, access such treatments is restricted by legal, medical, financial barriers. Circular breathwork may present a non-pharmacological hence more accessible alternative engage similar therapeutic processes. Scientific studies are only just emerging its physiological psychological mechanisms largely unknown. Here, we track experiential dynamics throughout session, comparing two forms breathwork: Holotropic Conscious-Connected breathwork. We that reduction in end-tidal CO2 pressure due deliberate hyperventilation significantly correlated ASC onset (r = -0.46; p < 0.001). Based on standard questionnaires (MEQ-30 11-DASC), the ASCs evoked resembled those produced psychedelics across several domains as ego dissolution, their depth predicted follow-on effects, including improved well-being reduced depressive symptoms. Further analysis showed different approaches highly outcomes. Our findings identify boundary conditions for arise context, shedding light functional well psychotherapeutic tool.
Language: Английский
Citations
2
Neuropharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 110314 - 110314
Published: Jan. 1, 2025
Language: Английский
Citations
1
Cerebral Cortex, Journal Year: 2024, Volume and Issue: 34(8)
Published: Aug. 1, 2024
Abstract Breathwork is an understudied school of practices involving intentional respiratory modulation to induce altered state consciousness (ASC). We simultaneously investigate the phenomenological and neural dynamics breathwork by combining Temporal Experience Tracing, a quantitative methodology that preserves temporal subjective experience, with low-density portable EEG devices. Fourteen novice participants completed course up 28 sessions—of 20, 40, or 60 min—in days, yielding neurophenomenological dataset 301 sessions. Using hypothesis-driven data-driven approaches, we found “psychedelic-like” experiences were associated increased Lempel-Ziv complexity during breathwork. Exploratory analyses showed aperiodic exponent power spectral density—but not oscillatory alpha power—yielded similar associations. Non-linear features, like exponent, neurally map both multidimensional composite positive experiences, aspects psychedelic-like experience states such as high bliss.
Language: Английский
Citations
6
Journal of Psychopharmacology, Journal Year: 2024, Volume and Issue: 38(10), P. 887 - 896
Published: Sept. 20, 2024
Background: Non-ordinary states of consciousness induced by psychedelics can be accompanied so-called “peak experiences,” characterized at the emotional level their intensity and positive valence. These experiences are strong predictors outcomes following psychedelic-assisted therapy, it is therefore important to better understand biology. Despite growing evidence that autonomic nervous system (ANS) plays an role in mediating experiences, its involvement psychedelic experience poorly understood. The aim this study was investigate what extent changes relative influence sympathetic (SNS) parasympathetic systems (PNS) over cardiac activity may reflect subjective short-acting N,N-Dimethyltryptamine (DMT). Methods: We derived measures SNS PNS from electrocardiograms 17 participants (11 males, mean age = 33.8 years, SD 8.3) while they received either DMT or placebo. Results: Results show joint (“sympathovagal coactivation”) positively related participants’ ratings “Spiritual Experience” “Insightfulness” during experience, also being improved well-being scores 2 weeks after session. In addition, we found state balance between two ANS branches balance”) before injection predicted as well subsequent sympathovagal coactivation. Conclusion: findings demonstrate psychedelic-induced peak pave way development biofeedback-based tools enhance therapy.
Language: Английский
Citations
5
Psychoactives, Journal Year: 2024, Volume and Issue: 3(3), P. 411 - 436
Published: Sept. 18, 2024
This narrative review explores the utilization of psychedelic states in therapeutic contexts, deliberately shifting focus from substances back to experiential phenomena which they induce, alignment with original meaning term “mind-manifesting”. provides an overview various used modern settings and ritualistic indigenous as well non-pharmacological methods that can arguably induce states, including breathwork, meditation, sensory deprivation. While occurrence mystical experiences seems be strongest predictor positive outcomes, literature this field yields several other psychological processes, such awe, perspective shifts, insight, emotional breakthrough, acceptance, re-experiencing memories, certain aspects challenging experiences, are significantly associated change. Additionally, we discuss detail experience-related changes metaphysical self-related beliefs their respective contributions observed outcomes. We conclude a purely medical neurobiological on health is reductive should not overshadow significance phenomenological understanding treating issues manifest subjective realities human individuals.
Language: Английский
Citations
4
Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)
Published: Dec. 13, 2023
Abstract Breathwork may offer simple tools for stress resilience. We conducted the largest parallel randomised-controlled trial on breathwork to date (NCT05676658) wherein 400 participants research platform Prolific were randomised, in blocks of 2 via remote software, coherent breathing at ~ 5.5 breaths/min or a matched attention-placebo 12 breaths/min, 10 min/day over 4 weeks. Participants blinded their allocated interventions, both which paced with equal inhalation:exhalation ratios. There no differences credibility and expectancy benefit between conditions. At primary timepoint post-intervention outcome subjective stress, there was significant group by time interaction ( F (1,377) = 0.089, p 0.765, η < 0.001) nor main effect 0.002, 0.961, 0.001), however 72.1, 0.001, 0.161). Similar results found 1-month follow-up secondary outcomes anxiety, depression wellbeing. overall improvements these mental health wellbeing from baseline across groups, yet magnitude this improvement not different arms. Accordingly, we measurable above well-designed placebo improving Methodological considerations recommendations robust future are discussed. Funder: Sasakawa Young Leaders Fellowship Fund, Tokyo, Japan.
Language: Английский
Citations
10
Indian Journal of Physiology and Pharmacology, Journal Year: 2025, Volume and Issue: 0, P. 1 - 9
Published: Feb. 3, 2025
Objectives: Continuous connected breathing (CCB) is a high-frequency technique without breath retention. This study examines changes in electroencephalogram (EEG) band power and heart rate variability (HRV) before, during after breathwork intervention of 3 rounds 40 CCB versus normal healthy volunteers. Materials Methods: Thirty-three volunteers, aged between 19 23 years, participated the ( n = 15; female 7; mean age 21.5 years) group, while control group consisted 18 individuals 18; male 11; 19.6 years). After acquiring baseline measures, engaged practice online for 10 days, continued with their usual activities. EEG HRV signals were recorded both groups days. Post-intervention, practised breathwork, breathed normally signal acquisition. was 1-min durations at five different time events (1 st , 4 th 5 7 min) according to protocol. continuously entire min, readings corresponding recording intervals analysed. acquired using an Enobio-8 cap dry electrodes pre-frontal (FP1 FP2), temporal (T7 T8), central (C3 C4) occipital (O1 O2) regions. data from Polar H7/H10 chest strap sensors through Bluetooth Elite app on android phone later processed Kubios software. MATLAB software extract delta (0– 3.5Hz), theta (4–7 Hz), alpha (8–13 beta (14–29 Hz) gamma frequencies (30–50 Hz). The arranged as before-after statistically analysed within between-group t -tests significance means. Results: There overall quantitative change −2 units −0.03 group. A significant decrease found (−2.27), (−1.7), (−1.8) (−2.27) brain waves (FP1, FP8), (T7, T8) (O1, regions compared before increase (+2.8) higher left right hemisphere. Bilateral average ranged −1.6 −2.6 −0.1 +4.9 parameters reduced but significance. improved though not significant. Conclusion: days breathworks (3 rounds) min/day may reduce delta, theta, waves. It help maintain autonomic balance recovery phase initial breathwork. Further studies are recommended test consistency outcomes.
Language: Английский
Citations
0
BMJ Open, Journal Year: 2025, Volume and Issue: 15(2), P. e094110 - e094110
Published: Feb. 1, 2025
Introduction Cognitive–behavioural therapy (CBT) works—but not equally well for all patients. Less than 50% of patients with internalising disorders achieve clinically meaningful improvement, negative consequences and healthcare systems. The research unit (RU) 5187 seeks to improve this situation by an in-depth investigation the phenomenon treatment non-response (TNR) CBT. We aim identify bio-behavioural signatures associated TNR, develop predictive models applicable individual enhance utility analytics collecting a naturalistic cohort high ecological validity outpatient sector. Methods analysis RU is composed nine subprojects (SPs), spanning from clinical, machine learning neuroimaging science service projects particular questions on psychological, electrophysiological/autonomic, digital neural TNR. clinical study SP 1 comprises four-centre, prospective-longitudinal observational trial where we recruit 585 wide range (specific phobia, social anxiety disorder, panic agoraphobia, generalised obsessive–compulsive post-traumatic stress unipolar depressive disorders) using minimal exclusion criteria. Our experimental focus lies emotion (dys)-regulation as putative key mechanism CBT use state-of-the-art methods single-patient predictions, incorporating pretrained convolutional networks high-dimensional data multiple kernel integrate information various modalities. aims advance precision psychotherapy identifying regulation-based biobehavioural markers setting up multilevel assessment optimal predictors ecologically valid sample apply findings in diverse settings, thereby addressing needs vulnerable Ethics dissemination has received ethical approval Institutional Committee Department Psychology at Humboldt-Universität zu Berlin (approval no. 2021-01) Charité-Universitätsmedizin EA1/186/22). Results will be disseminated through peer-reviewed journals presentations national international conferences. Deidentified scripts made available researchers within via secure server, line guidelines participant consent. In compliance European German protection regulations, patient publicly open frameworks but may shared external reasonable request under appropriate agreements. Trial registration number DRKS00030915.
Language: Английский
Citations
0
Journal of Obsessive-Compulsive and Related Disorders, Journal Year: 2025, Volume and Issue: unknown, P. 100951 - 100951
Published: March 1, 2025
Language: Английский
Citations
0
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: Feb. 22, 2024
Abstract Breathwork is a term for an understudied school of practices that involve the intentional modulation respiration to induce altered state consciousness (ASC). We map here neural dynamics mental content during breathwork, using neurophenomenological approach by combining Temporal Experience Tracing, quantitative phenomenological methodology preserves temporal subjective experience, with low-density portable EEG devices every session. Fourteen novice participants completed series up 28 breathwork sessions - 20, 40 or 60 minutes in days, yielding dataset 301 sessions. Using hypothesis-driven and data-driven approaches, we found positive ‘psychedelic-like’ experiences occurred within were associated increased Lempel-Ziv complexity. Further, exploratory analyses showed aperiodic exponent power spectral density (PSD) but not oscillatory alpha was also these psychedelic-like substates. demonstrate strength this framework, maximising concurrent data acquisition brain activity multiple experiential dimensions. Non-linear aspects dynamics, like complexity PSD, neurally both complex composite experiences, experience states such as high bliss.
Language: Английский
Citations
1