Impact of Physical Activity, Sedentary Behavior, and Basal Metabolic Rate on PTSD, Depression, and Emotional Instability DOI Creative Commons

Tianyi Lyu,

Haonan Qian,

Sung-Pil Chung

et al.

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(11), P. 1071 - 1071

Published: Oct. 27, 2024

Objective: This study aimed to investigate the potential associations between physical activity, sedentary behavior, and basal metabolic rate (BMR) with post-traumatic stress disorder (PTSD), major depressive (MDD), emotional instability (EI) using bidirectional Mendelian randomization (MR). Additionally, it sought identify key molecular mechanisms underlying through a comprehensive bioinformatic analysis. Methods: MR analyses utilizing genome-wide association (GWAS) data were conducted estimate effects of BMR on PTSD, MDD, EI. Sensitivity performed assess robustness findings. Concurrently, analysis was executed gene expression datasets (GSE53987 GSE21138) derived from emotionally unstable patients. encompassed differential differentially expressed genes (DEGs), followed by an functional enrichment uncover pathways associated Results: The revealed that increased activity may have protective effect against albeit inconsistent MDD Sedentary behavior demonstrated minimal or identified 114 DEGs EI, YWHAB, SRRM2, MST1, HDAC10, HSPA1A highlighted as significant genes. these unveiled potentially involved in pathology instability. Conclusions: Physical appears protect whereas its EI are less definitive. findings offer deeper understanding pinpointing specific serve therapeutic targets. Further research is warranted elucidate intricate interactions mechanisms.

Language: Английский

Advanced autism detection and visualization through XGBoost algorithm for fNIRS hemo-dynamic signals DOI Creative Commons
Sajid Farooq, Hailun He, Deyu Guo

et al.

Expert Systems with Applications, Journal Year: 2025, Volume and Issue: unknown, P. 127013 - 127013

Published: March 1, 2025

Language: Английский

Citations

0
Exploring Inter‐Brain Coherence Between Fathers and Infants During Maternal Storytelling: An fNIRS Hyperscanning Study DOI Creative Commons

Xin Zhou,

Xuancu Hong,

Patrick C. M. Wong

et al.

Infant and Child Development, Journal Year: 2025, Volume and Issue: 34(2)

Published: Feb. 26, 2025

ABSTRACT The current study examined the inter‐brain coherence (IBC) between 34 dyads of fathers and infants 7–9 months age using functional near‐infrared spectroscopy (fNIRS). We specifically focused on father–infant IBC to broaden empirical base beyond mother–infant connections, as former has received limited attention. There were three conditions: a baseline condition two task conditions when infant adult participant jointly listened maternal storytelling in Cantonese infant‐directed speech (IDS) adult‐directed (ADS). Father–infant was compared with stranger–infant same experimental settings. Our results found that greater ADS but not IDS condition, IBC. Further, showed than no significance conditions. These identified different connection mechanisms dyads. pattern is driven by neural entrainment mothers' speech, whereas more resistant behaviours co‐presence both parents.

Language: Английский

Citations

0
Language-specific Tonal Features Drive Speaker-Listener Neural Synchronization DOI Creative Commons
Gangyi Feng, Hong Chen, Xiangbin Teng

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Abstract Verbal communication transmits information across diverse linguistic levels, with neural synchronization (NS) between speakers and listeners emerging as a putative mechanism underlying successful exchange. However, the specific speech features driving this how language-specific versus universal characteristics facilitate transfer remain poorly understood. We developed novel content-based interbrain encoding model to disentangle contributions of acoustic speaker-listener NS during Mandarin storytelling listening, measured via magnetoencephalography (MEG). Results revealed robust throughout frontotemporal-parietal networks systematic time lags production perception. Crucially, suprasegmental lexical tone (tone categories, pitch height, contour), essential for meaning in Mandarin, contributed more significantly than either elements or segmental units (consonants vowels). These tonal generated distinctive spatiotemporal patterns, creating “communication channels” that facilitated efficient representation sharing interlocutors. Furthermore, strength patterns driven by these predicted success. findings demonstrate mechanisms shared representations verbal exchange highlight can shape coupling optimize human communication.

Language: Английский

Citations

0
Interbrain synchrony attenuation during a peer cooperative task in young children with autistic traits –an EEG hyperscanning study DOI Creative Commons
I‐Chun Chen, Hao‐Che Hsu, Chia‐Ling Chen

et al.

NeuroImage, Journal Year: 2025, Volume and Issue: 312, P. 121217 - 121217

Published: April 15, 2025

Young children with autism spectrum disorder (ASD) traits frequently encounter difficulties in peer interaction. Assessing interaction performance is crucial but challenging within the clinical diagnostic paradigm of ASD. Hyperscanning, which simultaneously monitors brain activity multiple individuals, has become a popular tool for assessing social interaction's neural features. The present study aims to investigate brain-to-brain connectivity between child-dyads engaged game-like collaborative task via hyperscanning electroencephalogram (EEG) approach. final sample comprised 66 young children: 18 child dyads typical development (TD), TD-TD, and 15 ASD matched TD, TD-ASD. indicated depressed level dyad group as responder, notable decrease observed beta oscillation over right parietal left temporal coupling subjects. A pattern that differed from TD-TD was identified regard full-band right-to-right region. It exhibited enhanced following completion task, not case TD-ASD group. Significant correlations were scores on symptom rating scale selected significant interbrain index. application EEG demonstrated participating autistic an attenuated apparently distinct alteration comparison control These findings highlight value physiologically based measures informing etiological interventional studies neuropsychiatry.

Language: Английский

Citations

0
Relational Neuroscience: insights from hyperscanning research DOI Creative Commons
Sara De Felice, Tara Chand, Ilona Croy

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2024, Volume and Issue: 169, P. 105979 - 105979

Published: Dec. 13, 2024

Humans are highly social, typically without this ability requiring noticeable efforts. Yet, such social fluency poses challenges both for the human brain to compute and scientists study. Over last few decades, neuroscientific research of sociality has witnessed a shift in focus from single-brain analysis complex dynamics occurring across several brains, posing questions about what these mean how they relate multifaceted behavioural models. We propose term 'Relational Neuroscience' collate interdisciplinary field devoted modelling inter-brain subserving connections, spanning real-time joint experiences long-term bonds. Hyperscanning, i.e., simultaneously measuring activity multiple individuals, proven be promising technique investigate dynamics. Here, we discuss hyperscanning can help within Relational Neuroscience, considering variety subfields, including cooperative interactions dyads groups, empathy, attachment bonding, developmental neuroscience. While presenting Neuroscience light hyperscanning, our discussion also takes into account behaviour, physiology endocrinology properly interpret contexts. consider strengths but limitations caveats answer interacting people. The aim is provide an integrative framework future work build better theories contexts subfields model sociality.

Language: Английский

Citations

3
Impact of Physical Activity, Sedentary Behavior, and Basal Metabolic Rate on PTSD, Depression, and Emotional Instability DOI Creative Commons

Tianyi Lyu,

Haonan Qian,

Sung-Pil Chung

et al.

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(11), P. 1071 - 1071

Published: Oct. 27, 2024

Objective: This study aimed to investigate the potential associations between physical activity, sedentary behavior, and basal metabolic rate (BMR) with post-traumatic stress disorder (PTSD), major depressive (MDD), emotional instability (EI) using bidirectional Mendelian randomization (MR). Additionally, it sought identify key molecular mechanisms underlying through a comprehensive bioinformatic analysis. Methods: MR analyses utilizing genome-wide association (GWAS) data were conducted estimate effects of BMR on PTSD, MDD, EI. Sensitivity performed assess robustness findings. Concurrently, analysis was executed gene expression datasets (GSE53987 GSE21138) derived from emotionally unstable patients. encompassed differential differentially expressed genes (DEGs), followed by an functional enrichment uncover pathways associated Results: The revealed that increased activity may have protective effect against albeit inconsistent MDD Sedentary behavior demonstrated minimal or identified 114 DEGs EI, YWHAB, SRRM2, MST1, HDAC10, HSPA1A highlighted as significant genes. these unveiled potentially involved in pathology instability. Conclusions: Physical appears protect whereas its EI are less definitive. findings offer deeper understanding pinpointing specific serve therapeutic targets. Further research is warranted elucidate intricate interactions mechanisms.

Language: Английский

Citations

0