The impact of the war in Ukraine on the physical and sexual development of girls with menstrual disorders

CHILD`S HEALTH, Journal Year: 2025, Volume and Issue: 20(1), P. 1 - 8

Published: March 5, 2025

Background. Puberty and the formation of menstrual function are significant stressors for a girl. Traumatic war experience can deepen maladaptive reactions body lead to more serious consequences disorders. The purpose study was investigate features changes in physical sexual maturation girls with disorders under influence long stay front-line city. Materials methods. One hundred fifty-three adolescent aged 11–18 years were examined, including 69 patients abnormal uterine bleeding (AUB) 84 oligomenorrhea (OM), who resided comparison group similar treated at pediatric gynecology department State Institution “Institute Children Adolescents Health Care” 2019–2021. Clinical anthropometry performed assess development, mass index calculated. main indicators degree development secondary sex characteristics (breast pubic axillary hair), time onset first menstruation. Results. Slightly than half OM (51.9 %) third AUB (37.1 had growth within normative values before start full-scale war. During war, tendency decrease these noted. Among deviations both during precocious puberty tall stature prevailed. Stay combat zone leads proportion adolescents physiological index. number excess weight obesity is significantly increasing (in AUB, from 16.7 % 32.4 P < 0.001; OM, 12.3 33.3 0.0001). A increase among 11–13-year-old has been recorded 75 83.9 0.05; 38.5 92.3 0.000001). age menarche probably decreased due early percentage relation total those surveyed increased 18.2 31.9 0.01; 8.5 14.3 0.02). Conclusions. most important impact stress on body, which be used as main, evident reliable criteria adverse course against background

Language: Английский

The relationship between psychological stress and ovulatory disorders and its molecular mechanisms: a narrative review

Journal of Psychosomatic Obstetrics & Gynecology, Journal Year: 2024, Volume and Issue: 45(1)

Published: Oct. 22, 2024

This narrative review explores the relationship between psychological stress and ovulatory disorders, focusing on molecular mechanisms involved. Ovulation is regulated by hypothalamus-pituitary-ovarian (HPO) axis, disruptions in this axis can lead to dysfunction. Chronic affects HPO resulting abnormalities hypothalamus hormone secretion, pituitary release, ovarian function. These cause ovulation disorders menstrual irregularities. The which involve alterations neuropeptides hormones, activation of hypothalamic-pituitary-adrenal (HPA) impairment follicular development, generation oxidative stress, decline reserve Understanding these crucial for developing interventions restore reproductive health. Psychological interventions, such as cognitive-behavioral therapy, have shown promise improving pregnancy rates women with disorders. Further research needed explore specific optimize treatment strategies. Addressing factors essential managing health

Language: Английский