The Effect of Cigarette Smoking and Alcohol Consumption on Survival in Advanced Laryngeal Cancer DOI Open Access
Kamyar Iravani, Leila Malekmakan, Aida Doostkam

et al.

International Journal of Cancer Management, Journal Year: 2025, Volume and Issue: 18(1)

Published: April 26, 2025

Background: Laryngeal cancer is the second most common respiratory tract cancer, with a relative 5-year overall survival rate varying by tumor site. Objectives: This study aimed to evaluate of patients based on epidemiological factors, as well clinical and demographic data. Methods: The group consisted 150 advanced laryngeal who underwent total laryngectomy (TL). Demographic data, symptoms, risk characteristics, postoperative complications were analyzed. Results: rates after 1, 3, 5 years for 99.3%, 97.0%, 76.5%, respectively. Patients stage 3 disease had significantly higher five-year than those 4 (91.0% vs. 68.4%; log-rank: 12.6, P = 0.002). Kaplan-Meier curve showed that 1-year was worse among positive history alcohol consumption (45.8% 96.2%; 13.8, < 0.001). Although effect smoking not statistically significant due small number non-smoking patients, clinically, percentage smokers. Conclusions: Alcohol high in worsen prognosis reduce survival.

Language: Английский

The Effect of Cigarette Smoking and Alcohol Consumption on Survival in Advanced Laryngeal Cancer DOI Open Access
Kamyar Iravani, Leila Malekmakan, Aida Doostkam

et al.

International Journal of Cancer Management, Journal Year: 2025, Volume and Issue: 18(1)

Published: April 26, 2025

Background: Laryngeal cancer is the second most common respiratory tract cancer, with a relative 5-year overall survival rate varying by tumor site. Objectives: This study aimed to evaluate of patients based on epidemiological factors, as well clinical and demographic data. Methods: The group consisted 150 advanced laryngeal who underwent total laryngectomy (TL). Demographic data, symptoms, risk characteristics, postoperative complications were analyzed. Results: rates after 1, 3, 5 years for 99.3%, 97.0%, 76.5%, respectively. Patients stage 3 disease had significantly higher five-year than those 4 (91.0% vs. 68.4%; log-rank: 12.6, P = 0.002). Kaplan-Meier curve showed that 1-year was worse among positive history alcohol consumption (45.8% 96.2%; 13.8, < 0.001). Although effect smoking not statistically significant due small number non-smoking patients, clinically, percentage smokers. Conclusions: Alcohol high in worsen prognosis reduce survival.

Language: Английский

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