VR Cognitive-based Intervention for Enhancing Cognitive Functions and Well-being in Older Adults with Mild Cognitive Impairment: Behavioral and EEG Evidence
Psychosocial Intervention,
Journal Year:
2025,
Volume and Issue:
34(1), P. 37 - 51
Published: Jan. 1, 2025
Objective:
Mild
cognitive
impairment
(MCI)
has
been
recognized
as
a
window
of
opportunity
for
therapeutic
and
preventive
measures
to
slow
decline.
The
current
study
investigated
the
efficacy
virtual
reality
(VR)
cognitive-based
intervention
on
verbal
visuospatial
short-term
memory
(STM),
executive
functions
(EFs),
wellbeing
among
older
adults
with
without
MCI.
Method:
immersive
VR
comprised
eight
60-minute
sessions,
held
twice
week
over
span
30
days.
participants
consisted
31
non-MCI
in
experimental
group
(mean
age
±
SD
=
66.31
3.12
years),
29
MCI
68.19
5.03
control
64.97
3.35
years).
dependent
variables
were
assessed
by
using
battery
computerized
test,
well-being
people
questionnaire
resting-state
EEG.
A
repeated-measures
ANCOVA
was
employed
examine
effects
developed
intervention.
Results:
Significant
improvements
observed
both
STMs
EFs
following
intervention,
indicated
behavioral
EEG
findings,
ranging
from
small
large
effect
sizes
(i.e.,
.05-.17).
However,
enhanced
specifically
group,
F(2,
87)
6.78,
p
.01,
.11.
Conclusions:
present
findings
lend
support
interventions
across
clinical
non-clinical
populations.
These
results
underscore
immediate
impact
multimodal
assessments,
including
neurophysiological
changes,
cognitive,
outcomes.
Language: Английский
Parallel electrophysiological abnormalities due to COVID‐19 infection and to Alzheimer's disease and related dementia
Alzheimer s & Dementia,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 29, 2024
Many
coronavirus
disease
2019
(COVID-19)
positive
individuals
exhibit
abnormal
electroencephalographic
(EEG)
activity
reflecting
"brain
fog"
and
mild
cognitive
impairments
even
months
after
the
acute
phase
of
infection.
Resting-state
EEG
abnormalities
include
slowing
(reduced
alpha
rhythm;
increased
slow
waves)
epileptiform
activity.
An
expert
panel
conducted
a
systematic
review
to
present
compelling
evidence
that
deficits
due
COVID-19
Alzheimer's
related
dementia
(ADRD)
are
driven
by
overlapping
pathologies
neurophysiological
abnormalities.
seen
in
patients
resemble
those
observed
early
stages
neurodegenerative
diseases,
particularly
ADRD.
It
is
proposed
similar
Long
COVID
ADRD
parallel
neuroinflammation,
astrocyte
reactivity,
hypoxia,
neurovascular
injury.
These
underpinning
decline
can
be
detected
routine
exams.
Future
research
will
explore
value
monitoring
for
predicting
long-term
outcomes
efficacy
therapeutic
interventions.
HIGHLIGHTS:
Abnormal
intrinsic
electrophysiological
brain
activity,
such
as
EEG,
reduced
wave,
characteristic
findings
patients.
have
potential
neural
biomarkers
identify
neurological
complications
at
stage
disease,
assist
clinical
assessment,
assess
risk
Similar
typically
with
impairments,
Evidence
presented
supports
idea
resulting,
least
part,
from
neuroinflammatory
mechanisms
reactivity.
Identifying
common
biological
highlight
critical
underlying
disorders
decline.
elucidates
questions
regarding
impairment
not
yet
been
adequately
investigated.
Language: Английский
Individual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
Behavioural Brain Research,
Journal Year:
2024,
Volume and Issue:
471, P. 115140 - 115140
Published: July 4, 2024
Subjective
memory
complaints
(SMCs)
are
a
disorder
that
often
precedes
mild
cognitive
impairment
(MCI)
or
Alzheimer's
disease
(AD).
Both
individual
alpha
rhythms
and
reserve
(CR)
represent
key
features
of
SMCs
provide
useful
tools
to
characterize
predict
the
course
disorder.
We
studied
whether
older
people
with
may
also
present
some
abnormal
resting
state
electroencephalogram
(rsEEG)
rhythms,
associated
CR.
To
do
this,
eyes-closed
rsEEG
were
recorded
in
68
without
SMCs.
The
indexes
alpha/theta
transition
frequency
(TF)
peak
(IAFp)
computed.
TF
IAFp
used
determine
alpha1,
alpha2,
alpha3
power
frequency.
Results
indicated
no
differences
between
controls.
group
showed
reduction
comparison
Specifically,
women
characterized
by
significant
decrease
compared
control
women.
Furthermore,
only
group,
greater
CR
was
slow
IAFp.
In
sum,
these
results
suggest
two
stable
not
influenced
presence
However,
alpha3,
as
observed
SMCs,
shows
an
posterior
at
power.
Finally,
compensatory
mechanisms
appear
interact
neurophysiological
underlie
regulation
rhythms.
Language: Английский
Neurophysiological markers of early cognitive decline in older adults: a mini-review of electroencephalography studies for precursors of dementia
Mutsuhide Tanaka,
No information about this author
Emi Yamada,
No information about this author
Futoshi Mori
No information about this author
et al.
Frontiers in Aging Neuroscience,
Journal Year:
2024,
Volume and Issue:
16
Published: Oct. 18, 2024
The
early
detection
of
cognitive
decline
in
older
adults
is
crucial
for
preventing
dementia.
This
mini-review
focuses
on
electroencephalography
(EEG)
markers
dementia-related
precursors,
including
subjective
decline,
memory
complaints,
and
frailty.
We
present
recent
findings
from
EEG
analyses
identifying
high
dementia
risk
adults,
with
an
emphasis
conditions
that
precede
mild
impairment.
also
cover
event-related
potentials,
quantitative
markers,
microstate
analysis,
functional
connectivity
approaches.
Moreover,
we
discuss
the
potential
these
neurophysiological
as
well
their
correlations
related
biomarkers.
integration
data
advanced
artificial
intelligence
technologies
shows
promise
predicting
trajectory
neurodegenerative
disorders.
Although
challenges
remain
its
standardization
clinical
application,
EEG-based
approaches
offer
non-invasive,
cost-effective
methods
individuals
at
dementia,
which
may
enable
earlier
interventions
personalized
treatment
strategies.
Language: Английский
The Neurophysiological Effects of Virtual Reality Application and Perspectives of Using for Multitasking Training in Cardiac Surgery Patients: Pilot Study
Applied Sciences,
Journal Year:
2024,
Volume and Issue:
14(23), P. 10893 - 10893
Published: Nov. 25, 2024
Background:
The
use
of
virtual
reality
(VR)
has
great
potential
for
medical
research
and
practice,
which
can
help
expand
rehabilitation
activities.
This
study
aimed
to
evaluate
the
acceptability
feasibility
original
protocol
VR
multitasking
cognitive
training
(CT)
in
both
a
healthy
group
cardiac
surgery
patients.
Methods:
A
specialized
hardware
software
complex
was
developed
tested
on
25
practically
individuals,
mean
age
22.9
years
(SD
2.57),
patients,
62.2
7.35).
participants
were
instructed
complete
one
session
CT
within
complex.
Psychometric
testing
EEG
studies
conducted.
Results:
All
highly
accepting
intended
future
use,
attitude,
pleasure
training.
subjects
demonstrated
statistically
significant
improvement
attention
spatial
skills
after
(p
˂
0.05).
data
revealed
increase
alpha
power
compared
pre-experiment
levels
0.0001).
theta/alpha
ratio
significantly
decreased
as
baseline
Conclusions:
obtained
indicate
that
using
is
acceptable
easy
individuals
Language: Английский