From single words to sentence production: Shared cortical representations but distinct temporal dynamics DOI Creative Commons
Adam Milton Morgan, Orrin Devinsky, Werner Doyle

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 31, 2024

Sentence production is the uniquely human ability to transform complex thoughts into strings of words. Despite importance this process, language research has primarily focused on single It remains an untested assumption that insights from literature generalize more naturalistic utterances like sentences. Here, we investigate using high-resolution neurosurgical recordings (ECoG) and overt experiment where patients produce six words in isolation (picture naming) sentences (scene description). We trained machine learning models identify unique brain activity pattern for each word during picture naming, used these patterns decode which were processing while they produced Our findings reveal share cortical representations across tasks. In sensorimotor cortex, consistently activated order said sentence. However, inferior middle frontal gyri (IFG MFG), processed depended syntactic structure This dynamic interplay between sentence reveals not simply a sequence tasks, highlights regional division labor within network. Finally, argue dynamics prefrontal cortex may impose subtle pressure evolution, explaining why nearly all world's languages position subjects before objects.

Language: Английский

Processing Argument Structure and Syntactic Complexity in People with Schizophrenia Spectrum Disorders DOI
Chiara Barattieri di San Pietro, Elena Barbieri, Marco Marelli

et al.

Journal of Communication Disorders, Journal Year: 2022, Volume and Issue: 96, P. 106182 - 106182

Published: Jan. 11, 2022

Language: Английский

Citations

8
Canonical Sentence Processing and the Inferior Frontal Cortex: Is There a Connection? DOI Creative Commons
Nicholas Riccardi, Chris Rorden, Julius Fridriksson

et al.

Neurobiology of Language, Journal Year: 2022, Volume and Issue: 3(2), P. 318 - 344

Published: Jan. 1, 2022

Abstract The role of left inferior frontal cortex (LIFC) in canonical sentence comprehension is controversial. Many studies have found involvement LIFC production or complex comprehension, but negative mixed results are often simple sentences. We used voxel-, region-, and connectivity-based lesion symptom mapping (VLSM, RLSM, CLSM) left-hemisphere chronic stroke survivors to investigate while controlling for lexical-semantic, executive, phonological processes. investigated how damage disrupted white matter connectivity two other language-related regions, the anterior temporal lobe (LATL) posterior temporal-inferior parietal area (LpT-iP), affected comprehension. VLSM RLSM revealed that was not associated with measured by a sensibility judgment task. instead impairments lexical semantic similarity task high semantic/executive demands. Damage LpT-iP, specifically middle gyrus (pMTG), predicted worse after visual access, knowledge, auditory-verbal short-term memory (STM), auditory single-word suggesting pMTG vital language CLSM disruption left-lateralized white-matter connections from LATL LpT-iP performance tasks related word STM. However, were accounted task, which had This suggests relevant when task-related demands high.

Language: Английский

Citations

7
Associations between brain network, puberty, and behaviors in boys with Klinefelter syndrome DOI
Rihui Li, Lara C. Foland‐Ross, Tracy L. Jordan

et al.

European Child & Adolescent Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: June 21, 2024

Language: Английский

Citations

1
Brain-wide functional connectivity alterations and their cognitive correlates in subjective cognitive decline DOI Creative Commons

Shaochun Huang,

Siyu Wang, Zigang Che

et al.

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: Aug. 1, 2024

Individuals with subjective cognitive decline (SCD) are at risk of developing Alzheimer's Disease (AD). Traditional seed-based analysis has shown biased functional connectivity (FC) in SCD individuals. To investigate unbiased altered FC by the brain-wide association study (BWAS) and to determine its cognition

Language: Английский

Citations

1
From single words to sentence production: Shared cortical representations but distinct temporal dynamics DOI Creative Commons
Adam Milton Morgan, Orrin Devinsky, Werner Doyle

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 31, 2024

Sentence production is the uniquely human ability to transform complex thoughts into strings of words. Despite importance this process, language research has primarily focused on single It remains an untested assumption that insights from literature generalize more naturalistic utterances like sentences. Here, we investigate using high-resolution neurosurgical recordings (ECoG) and overt experiment where patients produce six words in isolation (picture naming) sentences (scene description). We trained machine learning models identify unique brain activity pattern for each word during picture naming, used these patterns decode which were processing while they produced Our findings reveal share cortical representations across tasks. In sensorimotor cortex, consistently activated order said sentence. However, inferior middle frontal gyri (IFG MFG), processed depended syntactic structure This dynamic interplay between sentence reveals not simply a sequence tasks, highlights regional division labor within network. Finally, argue dynamics prefrontal cortex may impose subtle pressure evolution, explaining why nearly all world's languages position subjects before objects.

Language: Английский

Citations

1