Neural tracking of speech envelope does not unequivocally reflect intelligibility

NeuroImage, Journal Year: 2023, Volume and Issue: 272, P. 120040 - 120040

Published: March 17, 2023

During listening, brain activity tracks the rhythmic structures of speech signals. Here, we directly dissociated contribution neural envelope tracking in processing acoustic cues from that related to linguistic processing. We examined changes associated with comprehension Noise-Vocoded (NV) using magnetoencephalography (MEG). Participants listened NV sentences a 3-phase training paradigm: (1) pre-training, where stimuli were barely comprehended, (2) exposure original clear version stimulus, and (3) post-training, same gained intelligibility phase. Using this paradigm, tested if responses signal was modulated by its without any change structure. To test influence spectral degradation on independently training, participants two types (4-band 2-band speech), but only trained understand 4-band speech. Significant observed delta range relation However, failed find direct effect both theta ranges, auditory regions-of-interest whole-brain sensor-space analyses. This suggests acoustics greatly response envelope, caution needs be taken when choosing control signals for speech-brain analyses, considering slight parameters can have strong effects response.

Language: Английский

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Spatiotemporal dynamics characterise spectral connectivity profiles of continuous speaking and listening

PLoS Biology, Journal Year: 2023, Volume and Issue: 21(7), P. e3002178 - e3002178

Published: July 21, 2023

Speech production and perception are fundamental processes of human cognition that both rely on intricate processing mechanisms still poorly understood. Here, we study these by using magnetoencephalography (MEG) to comprehensively map connectivity regional brain activity within the speech envelope during continuous speaking listening. Our results reveal not only a partly shared neural substrate for but also dissociation in space, delay, frequency. Neural motor frontal areas is coupled succeeding delta band (1 3 Hz), whereas coupling theta range follows temporal speaking. showed separation bottom-up top-down signalling distinct frequency bands show frequency-specific channels support These findings further shed light complex interplay between different regions involved perception.

Language: Английский

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Speech onsets and sustained speech contribute differentially to delta and theta speech tracking in auditory cortex

Cerebral Cortex, Journal Year: 2023, Volume and Issue: 33(10), P. 6273 - 6281

Published: Jan. 10, 2023

Abstract When we attentively listen to an individual’s speech, our brain activity dynamically aligns the incoming acoustic input at multiple timescales. Although this systematic alignment between ongoing and speech in auditory areas is well established, events that drive phase-locking are not fully understood. Here, use magnetoencephalographic recordings of 24 human participants (12 females) while they were listening a 1 h story. We show whereas speech–brain coupling associated with sustained fluctuations envelope theta-frequency range (4–7 Hz), tracking low-frequency delta (below Hz) was strongest around onsets like beginning sentence. Crucially, bilateral after onsets, proposing during continuous perception driven by onsets. conclude both components contribute differentially delta- bands, orchestrating sampling speech. Thus, results suggest temporal dissociation acoustically oscillatory tracking, providing valuable implications for orchestration time scales.

Language: Английский

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Beyond linear neural envelope tracking: a mutual information approach

Journal of Neural Engineering, Journal Year: 2023, Volume and Issue: 20(2), P. 026007 - 026007

Published: Feb. 22, 2023

Objective.The human brain tracks the temporal envelope of speech, which contains essential cues for speech understanding. Linear models are most common tool to study neural tracking. However, information on how is processed can be lost since nonlinear relations precluded. Analysis based mutual (MI), other hand, detect both linear and gradually becoming more popular in field Yet, several different approaches calculating MI applied with no consensus approach use. Furthermore, added value techniques remains a subject debate field. The present paper aims resolve these open questions.Approach.We analyzed electroencephalography (EEG) data participants listening continuous analyses models.Main results.Comparing approaches, we conclude that results reliable robust using Gaussian copula approach, first transforms standard Gaussians. With this analysis valid technique studying Like models, it allows spatial interpretations processing, peak latency analyses, applications multiple EEG channels combined. In final analysis, tested whether components were response by removing all data. We robustly detected single-subject level analysis.Significance.We demonstrate processes way. Unlike detects such relations, proving its addition, retains characteristics an advantage when complex (nonlinear) deep networks.

Language: Английский

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Speech and music recruit frequency-specific distributed and overlapping cortical networks

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Feb. 8, 2024

To what extent does speech and music processing rely on domain-specific domain-general neural networks? Using whole-brain intracranial EEG recordings in 18 epilepsy patients listening to natural, continuous or music, we investigated the presence of frequency-specific network-level brain activity. We combined it with a statistical approach which clear operational distinction is made between shared, preferred, domain-selective responses. show that majority focal activity shared processing. Our data also reveal an absence anatomical regional selectivity. Instead, responses are restricted distributed coherent oscillations, typical spectral fingerprints. work highlights importance considering natural stimuli dynamics their full complexity map cognitive functions.

Language: Английский

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Speech and music recruit frequency-specific distributed and overlapping cortical networks

eLife, Journal Year: 2024, Volume and Issue: 13

Published: July 22, 2024

To what extent does speech and music processing rely on domain-specific domain-general neural networks? Using whole-brain intracranial EEG recordings in 18 epilepsy patients listening to natural, continuous or music, we investigated the presence of frequency-specific network-level brain activity. We combined it with a statistical approach which clear operational distinction is made between shared , preferred, domain- selective responses. show that majority focal activity processing. Our data also reveal an absence anatomical regional selectivity. Instead, domain-selective responses are restricted distributed coherent oscillations, typical spectral fingerprints. work highlights importance considering natural stimuli dynamics their full complexity map cognitive functions.

Language: Английский

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Neural speech tracking contribution of lip movements predicts behavioral deterioration when the speaker's mouth is occluded

eNeuro, Journal Year: 2025, Volume and Issue: unknown, P. ENEURO.0368 - 24.2024

Published: Jan. 16, 2025

Observing lip movements of a speaker facilitates speech understanding, especially in challenging listening situations. Converging evidence from neuroscientific studies shows stronger neural responses to audiovisual stimuli compared audio-only stimuli. However, the interindividual variability this contribution movement information and its consequences on behavior are unknown. We analyzed source-localized magnetoencephalographic (MEG) 29 normal-hearing participants (12 female) speech, both with without wearing surgical face mask, presence or absence distractor speaker. Using temporal response functions (TRFs) quantify tracking, we show that are, general, enhanced when is challenging. After controlling for acoustics, contribute particularly present. extent visual tracking varied greatly among participants. Probing behavioral relevance, demonstrate individuals who higher terms drop comprehension an increase perceived difficulty mouth occluded by mask. By contrast, no effect was found not occluded. provide novel insights how varies revealing negative absent. Our results also offer potential implications objective assessments perception. Significance Statement In complex auditory environments, simultaneous conversations pose challenge comprehension. investigated level, aid such situations what observing enhances rely more deterioration wears Remarkably, case mask worn findings reveal differences applications

Language: Английский

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Dissociating prosodic from syntactic delta activity during natural speech comprehension

Current Biology, Journal Year: 2024, Volume and Issue: 34(15), P. 3537 - 3549.e5

Published: July 23, 2024

Decoding human speech requires the brain to segment incoming acoustic signal into meaningful linguistic units, ranging from syllables and words phrases. Integrating these constituents a coherent percept sets root of compositional meaning hence understanding. One important cue for segmentation in natural is prosodic cues, such as pauses, but their interplay with higher-level processing still unknown. Here, we dissociate neural tracking pauses multi-word chunks using magnetoencephalography (MEG). We find that manipulating regularity disrupts slow speech-brain bilaterally auditory areas (below 2 Hz) turn increases left-lateralized coherence higher-frequency activity at onsets (around 25-45 Hz). Critically, also chunks-defined short, bundles inter-word dependencies-are processed through rhythmic fluctuations low-frequency independently cues. Importantly, alignment chunk accuracy an encoding model bilateral frontal while controlling effect acoustics. Our findings provide novel insights basis perception, demonstrating both features (prosodic cues) abstract timescale are underpinned by electrophysiological delta frequency range.

Language: Английский

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The impact of ROI extraction method for MEG connectivity estimation: Practical recommendations for the study of resting state data.

NeuroImage, Journal Year: 2023, Volume and Issue: 284, P. 120424 - 120424

Published: Oct. 30, 2023

Magnetoencephalography and electroencephalography (M/EEG) seed-based connectivity analysis requires the extraction of measures from regions interest (ROI). M/EEG ROI-derived source activity can be treated in different ways. It is possible, for instance, to average each ROI's time series prior calculating measures. Alternatively, one compute maps element ROI dimensionality reduction obtain a single map. The impact these strategies on results still unclear. Here, we address this question within large MEG resting state cohort (N=113) simulated data. We consider 68 ROIs (Desikan-Kiliany atlas), two (phase locking value-PLV, its imaginary counterpart- ciPLV), three frequency bands (theta 4-8 Hz, alpha 9-12 beta 15-30 Hz). compare four methods: (i) mean, or (ii) PCA seed before computing connectivity, map (iii) average, (iv) maximum after seed. Hierarchical clustering then applied outputs across multiple strategies, followed by direct contrasts methods. Finally, are validated using set realistic simulations. show that ROI-based vary remarkably terms magnitude spatial distribution. Dimensionality procedures conducted more similar each-other, while approach most dissimilar other approaches. Although differences methods consistent bands, they influenced metric size. Greater were observed ciPLV than PLV, larger ROIs. Realistic simulations confirmed aggregation generally accurate but have lower specificity (higher rate false positive connections). Though computationally demanding, should preferred when higher sensitivity desired. Given remarkable procedures, caution warranted comparing studies applying

Language: Английский

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Neural speech tracking benefit of lip movements predicts behavioral deterioration when the speaker’s mouth is occluded

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: April 18, 2023

Abstract Observing lip movements of a speaker is known to facilitate speech understanding, especially in challenging listening situations. Converging evidence from neuroscientific studies shows enhanced processing audiovisual stimuli. However, the interindividual variability this visual benefit and its consequences on behavior are unknown. Here, we analyzed source-localized magnetoencephalographic (MEG) responses normal-hearing participants with or without an additional distractor speaker. Using temporal response functions (TRFs), show that neural are, general, when challenging. After conducting crucial control for acoustics, effectively contribute higher tracking, particularly present. extent varied greatly among participants. Probing behavioral relevance, individuals who more movement information terms stronger drop performance increase perceived difficulty mouth occluded by surgical face mask. By contrast, no effect was found not occluded. We provide novel insights how tracking varies individuals. Furthermore, reveal relevance demonstrating negative absent. Our results also offer potential implications future objective assessments perception.

Language: Английский

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