Neuroimaging for precision medicine in psychiatry
Leanne M. Williams,
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Susan Gabrieli
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Neuropsychopharmacology,
Journal Year:
2024,
Volume and Issue:
50(1), P. 246 - 257
Published: July 22, 2024
Language: Английский
Regional and whole-brain neurofunctional alterations during pain empathic processing of physical but not affective pain in migraine patients
Dan Liu,
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M. Li,
No information about this author
Heng Jiang
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et al.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 21, 2025
Abstract
Background
Accumulating
evidence
suggests
that
migraine
patients
present
abnormal
brain
responses
to
salient
sensory
and
emotional
stimuli.
However,
it
is
still
unclear
whether
this
a
generalized
or
domain-specific
phenomenon.
Employing
well-validated
fMRI
paradigm,
we
investigated
pain
empathic
reactivity
across
two
domains:
observation
of
physical
(noxious
stimulation)
affective
(facial
expressions).
On
the
basis
hyperexcitability/hyperreactivity
in
migraine,
hypothesized
both
dimensions
empathy.
Methods
We
collected
psychometric
data
from
21
matched
controls.
Univariate
multivariate
neuroimaging
analyses
were
utilized
examine
dysregulations
(a)
neural
meta-analytically
defined
shared
regions
pain-empathy
processing,
(b)
whole-brain
neurofunctional
signatures
empathy
(VPS,
Zhou
et
al.,
2020).
Logistic
regression
models
machine
learning-based
classification
employed
determine
differences
between
groups
(migraine
control).
Results
Migraine
exhibit
increased
during
for
bilateral
inferior
frontal
gyrus
(slightly
more
pronounced
on
right
side),
with
alterations
significantly
associated
experienced
attack.
level,
predictive
accuracy
VPS
was
shown
be
higher
as
compared
controls,
reaching
100%
accuracy.
Across
analyses,
did
not
find
altered
processing
pain.
Conclusion
Contrary
our
hypothesis,
results
indicate
responsivity,
localized
but
also
extending
subtle
whole
patterns,
stimuli,
Based
pathways
experimental
robustly
overlap,
these
specific
hyperresponsivity
pathways,
likely
playing
regulatory
role
modulating
pain-related
processes.
Finally,
underscore
translational
application
potential
neuroaffective
neuromarkers
pathological
Language: Английский
Self-navigating the “Island of Reil”: a systematic review of real-time fMRI neurofeedback training of insula activity
Translational Psychiatry,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: May 16, 2025
Real-time
fMRI
(rtfMRI)
neurofeedback
(NF)
is
a
novel
noninvasive
technique
that
permits
individuals
to
voluntarily
control
brain
activity.
The
crucial
role
of
the
insula
in
emotional
and
salience
processing
makes
it
one
most
commonly
targeted
regions
previous
rtfMRI
studies.
To
provide
an
overview
progress
field,
present
review
identified
25
studies
systematically
reviewed
key
characteristics
findings
these
We
found
rtfMRI-based
NF
training
efficient
for
modulating
activity
its
associated
behavioral/symptom-related
neural
changes.
Furthermore,
we
also
observed
maintenance
effect
self-regulation
ability
sustained
symptom
improvement,
which
importance
clinical
application.
However,
success
regulation
was
not
consistently
paralleled
by
changes,
suggesting
need
optimizing
protocol
enabling
more
robust
effects.
Principles
including
inclusion
well-designed
group/condition,
statistical
analyses
reporting
results
following
common
criteria
priori
determination
sample
sizes
as
well
pre-registration
are
highly
recommended.
In
summary,
believe
our
will
inspire
inform
both
basic
research
therapeutic
translation
intervention
mental
disorders
particularly
those
with
dysfunction.
Language: Английский
Heart Rate Variability and Interoception in Periodic Limb Movements in Sleep: Interference with Psychiatric Disorders?
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(20), P. 6129 - 6129
Published: Oct. 14, 2024
Periodic
limb
movements
in
sleep
(PLMS)
are
a
prevalent
disorder
characterized
by
rhythmic,
involuntary
of
the
lower
limbs,
such
as
dorsiflexion
ankle
and
extension
big
toe,
occurring
periodic
intervals
during
sleep.
These
often
linked
to
disrupted
autonomic
nervous
system
(ANS)
activity
altered
interoception.
Interoception
involves
perceiving
internal
bodily
states,
like
heartbeat,
breathing,
hunger,
temperature,
plays
crucial
role
maintaining
homeostasis
mind-body
connection.
This
review
explores
complex
relationships
between
PLMS,
heart
rate
variability
(HRV),
ANS
dysregulation,
their
impact
on
psychiatric
disorders.
By
synthesizing
existing
literature,
it
provides
insights
into
how
dysregulation
interoceptive
processes,
alongside
contribute
conditions.
The
highlights
potential
for
integrated
diagnostic
therapeutic
approaches
presents
cause-and-effect
model
illustrating
mutual
influence
disorders,
Language: Английский
Intranasal Oxytocin Improves Interoceptive Accuracy and Heartbeat-Evoked Potentials During a Cardiac Interoceptive Task
Menghan Zhou,
No information about this author
Lanqing Cheng,
No information about this author
Yibo Zhou
No information about this author
et al.
Biological Psychiatry Cognitive Neuroscience and Neuroimaging,
Journal Year:
2024,
Volume and Issue:
9(10), P. 1019 - 1027
Published: June 3, 2024
Language: Английский
PRIDASE 2024 guidelines for reporting diagnostic accuracy studies in endodontics: Explanation and elaboration
International Endodontic Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 19, 2024
Abstract
The
Preferred
Reporting
Items
for
Diagnostic
Accuracy
Studies
in
Endodontics
(PRIDASE)
2024
guidelines
are
based
on
the
Standards
of
(STARD)
2015
and
Clinical
Laboratory
Images
Publications
(CLIP)
principles,
with
addition
items
specifically
related
to
endodontics.
use
PRIDASE
by
authors
their
application
journals
during
peer
review
process
will
reduce
possibility
bias
enhance
quality
future
diagnostic
accuracy
studies.
consist
a
checklist
containing
11
domains
66
individual
items.
purpose
current
document
is
provide
an
explanation
each
item
checklist,
along
examples
from
literature
help
readers
understand
importance
offer
advice
those
developing
manuscripts.
A
link
elaboration
available
study
Designs
Endodontology
(PRIDE)
website
(
https://pride‐endodonticguidelines.org/pridase/
)
International
Endodontic
Journal
https://onlinelibrary.wiley.com/page/journal/13652591/homepage/pride‐guidelines.htm
).
Language: Английский