Flexibility of intrinsic neural timescales during distinct behavioral states DOI Creative Commons
Yasir Çatal, Kaan Keskin, Angelika Wolman

et al.

Communications Biology, Journal Year: 2024, Volume and Issue: 7(1)

Published: Dec. 19, 2024

Abstract Recent neuroimaging studies demonstrate a heterogeneity of timescales prevalent in the brain’s ongoing spontaneous activity, labeled intrinsic neural (INT). At same time, also reflect stimulus- or task-related activity. The relationship INT during activity with their involvement task states including behavior remains unclear. To address this question, we combined calcium imaging data spontaneously behaving mice and human electroencephalography (EEG) rest computational modeling. We obtained four primary findings: (i) distinct behavioral can be accurately predicted from INT, (ii) become longer compared to rest, (iii) change is correlated negatively variability (iv) mass modeling shows key role recurrent connections mediating rest-task INT. Extending current findings, our results show dynamic nature reflecting continuous through flexible modulation possibly mediated by connections.

Language: Английский

Common Currency Theory – Connecting neural and mental features through temporo-spatial dynamics DOI Creative Commons
Georg Northoff,

Andrea Buccellato,

Federico Zilio

et al.

Physics of Life Reviews, Journal Year: 2024, Volume and Issue: 52, P. 29 - 43

Published: Nov. 21, 2024

Despite major progress in our understanding of the brain, connection neural and mental features, that is, brain mind, remains yet elusive. In 2020 target paper ("Is temporospatial dynamics 'common currency' mind? Spatiotemporal Neuroscience") we proposed "Common currency hypothesis": temporo-spatial are shared by providing their connection. The current aims to further support extend original description such common into a first outline theory" (CCT) neuro-mental relationship. First, range examples thoughts, meditation, depression attention all lending temporal characteristics, (i.e. dynamics) both features. Second, now also show empirical how spatial i.e., topography, features; this is illustrated topographic reorganization states meditation. Third, considering theoretical terms, specify relationship distinct forms correspondences, ranging on continuum from simple complex. conclusion, initial hypothesis about key role an integrated mind-brain theory, (CCT).

Language: Английский

Citations

6
Test–retest reliability of resting-state EEG intrinsic neural timescales DOI
Xiaoling Tang, Shan Wang, Xinye Xu

et al.

Cerebral Cortex, Journal Year: 2025, Volume and Issue: 35(2)

Published: Feb. 1, 2025

Abstract Intrinsic neural timescales, which reflect the duration of information storage within local brain regions and capacity for integration, are typically measured using autocorrelation windows (ACWs). Extraction intrinsic timescales from resting-state activity has been extensively applied in psychiatric disease research. Given potential as a marker disorders, investigating their reliability is crucial. This study, an open-source database, aimed to evaluate test–retest ACW-0 ACW-50 under both eyes-open eyes-closed conditions across three sessions. The intraclass correlation coefficients (ICCs) were employed quantify timescales. Our results showed that exhibited good (ICC > 0.6) at whole-brain level different index types eye states. Spatially, except right temporal region condition, all other moderate-to-high ICCs. Over 60% electrodes demonstrated timescale ICCs conditions, with being more stable than ACW-50. Moreover, new dataset, above consistently reproduced. present study comprehensively assessed various providing robust evidence stability neuroscience psychiatry.

Language: Английский

Citations

0
From pre-stimulus activity to the contents of consciousness – A spatiotemporal view: reply to comments on “Beyond task response-Pre-stimulus activity modulates contents of consciousness" DOI
Georg Northoff, Federico Zilio, Jianfeng Zhang

et al.

Physics of Life Reviews, Journal Year: 2025, Volume and Issue: 53, P. 76 - 90

Published: Feb. 26, 2025

Language: Английский

Citations

0
Bridging the gap of brain and experience – Converging Neurophenomenology with Spatiotemporal Neuroscience DOI Creative Commons
Georg Northoff, Bianca Ventura

Neuroscience & Biobehavioral Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 106139 - 106139

Published: April 1, 2025

Neuroscience faces the challenge of connecting brain and mind, with mind manifesting in first-person experience while brain's neural activity can only be investigated third-person perspective. To connect mental states, neurophenomenology provides a methodological tool kit for systematically linking subjective objective observations activity. However, beyond providing systematic strategy ('disciplined circularity'), it leaves open how are related among themselves, independent our strategy. The recently introduced Spatiotemporal suggests that share commonly underlying feature as their "common currency", notably analogous spatiotemporal dynamics. Can inform to allow deeper more substantiative connection activity? goal paper is show Neurophenomenology converged integrated each other gain better understanding brain-mind connection. We describe convergence on theoretical grounds which, subsequently, illustrated by empirical examples like self, meditation, depression. In conclusion, we propose integration provide complementary insights, enrich both fields, allows connection, opens door developing novel approaches investigation.

Language: Английский

Citations

0
Flexibility of intrinsic neural timescales during distinct behavioral states DOI Creative Commons
Yasir Çatal, Kaan Keskin, Angelika Wolman

et al.

Communications Biology, Journal Year: 2024, Volume and Issue: 7(1)

Published: Dec. 19, 2024

Abstract Recent neuroimaging studies demonstrate a heterogeneity of timescales prevalent in the brain’s ongoing spontaneous activity, labeled intrinsic neural (INT). At same time, also reflect stimulus- or task-related activity. The relationship INT during activity with their involvement task states including behavior remains unclear. To address this question, we combined calcium imaging data spontaneously behaving mice and human electroencephalography (EEG) rest computational modeling. We obtained four primary findings: (i) distinct behavioral can be accurately predicted from INT, (ii) become longer compared to rest, (iii) change is correlated negatively variability (iv) mass modeling shows key role recurrent connections mediating rest-task INT. Extending current findings, our results show dynamic nature reflecting continuous through flexible modulation possibly mediated by connections.

Language: Английский

Citations

2