A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo

Neuron, Journal Year: 2021, Volume and Issue: 110(5), P. 770 - 782.e5

Published: Dec. 22, 2021

Language: Английский

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A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility

Cell, Journal Year: 2022, Volume and Issue: 185(18), P. 3390 - 3407.e18

Published: Sept. 1, 2022

Chemical synapses between axons and dendrites mediate neuronal intercellular communication. Here, we describe a synapse primary cilia: the axo-ciliary synapse. Using enhanced focused ion beam-scanning electron microscopy on samples with optimally preserved ultrastructure, discovered brainstem serotonergic cilia of hippocampal CA1 pyramidal neurons. Functionally, these are enriched in ciliary-restricted serotonin receptor, 5-hydroxytryptamine receptor 6 (5-HTR6). cilia-targeted sensor, show that opto- chemogenetic stimulation releases onto cilia. Ciliary 5-HTR6 activates non-canonical G

Language: Английский

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Spatiotemporal dynamics of noradrenaline during learned behaviour

Nature, Journal Year: 2022, Volume and Issue: 606(7915), P. 732 - 738

Published: June 1, 2022

Language: Английский

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A genetically encoded sensor for in vivo imaging of orexin neuropeptides

Nature Methods, Journal Year: 2022, Volume and Issue: 19(2), P. 231 - 241

Published: Feb. 1, 2022

Language: Английский

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A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments

Nature Biotechnology, Journal Year: 2023, Volume and Issue: 41(7), P. 944 - 957

Published: Jan. 2, 2023

Language: Английский

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