
Biomedicines, Journal Year: 2024, Volume and Issue: 12(11), P. 2539 - 2539
Published: Nov. 7, 2024
The interplay between socio-psychological factors and biological systems is pivotal in defining human health disease, particularly chronic non-communicable diseases. Recent advancements psychoneuroimmunology mitochondrial psychobiology have emphasized the significance of psychological as critical determinants disease onset, progression, recurrence, severity. These insights align with evolutionary biology, psychology, psychiatry, highlighting inherent social nature humans. This study proposes a theory that expands insulin's role beyond traditional metabolic functions, incorporating it into Mitochondrial Information Processing System (MIPS) exploring from an medicine perspective to explore its function processing responses. narrative review comprises data preclinical animal studies, longitudinal cohort cross-sectional machine learning analyses, randomized controlled trials, investigates insulin disease. result proposal for theoretical framework substance within socio-psycho-biological framework, emphasizing extensive roles Type 2 Diabetes Mellitus (T2DM) musculoskeletal disorders neurodegeneration exemplifies this narrative. We suggest further research towards comprehensive treatment protocol meeting expectations, where psychosocial interventions plays essential role. By supporting concept 'insulin resilience' suggesting use heart rate variability assess resilience, we aim provide integrative approach managing levels monitoring effectiveness interventions. strategy addresses broader factors, ultimately improving outcomes individuals T2DM complications while providing new
Language: Английский