Effect of combined oral contraceptive use on verbal memory function in healthy women
Archives of Women s Mental Health,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 19, 2025
Language: Английский
Evaluation of hippocampal volumes with MRI in Alzheimer’s disease
Chinese Journal of Academic Radiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: June 4, 2025
Language: Английский
Metabotropic NMDA Receptor Signaling Contributes to Sex Differences in Synaptic Plasticity and Episodic Memory
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 27, 2024
Men
generally
outperform
women
on
encoding
spatial
components
of
episodic
memory
whereas
the
reverse
holds
for
semantic
elements.
Here
we
show
that
female
mice
males
tests
non-spatial
aspects
("what",
"when"),
suggesting
human
findings
are
influenced
by
neurobiological
factors
common
to
mammals.
Analysis
hippocampal
synaptic
plasticity
mechanisms
and
revealed
unprecedented,
sex-specific
contributions
non-classical
metabotropic
NMDA
receptor
(NMDAR)
functions.
While
both
sexes
used
non-ionic
NMDAR
signaling
trigger
actin
polymerization
needed
consolidate
long-term
potentiation
(LTP),
GluN2B
subunit
antagonism
blocked
these
effects
in
only
had
corresponding
effect
memory.
Conversely,
blocking
estrogen
alpha
eliminated
stabilization
LTP
females
only.
The
results
sex
differences
critical
enduring
hippocampus
have
significant
consequences
memories.
Language: Английский
The role of sex hormones, oral contraceptive use, and its parameters on visuospatial abilities, verbal fluency, and verbal memory
Hormones and Behavior,
Journal Year:
2023,
Volume and Issue:
157, P. 105454 - 105454
Published: Nov. 18, 2023
Sex
hormones
can
cross
the
blood-brain
barrier
and
access
brain
regions
underlying
higher-order
cognition.
Containing
synthetic
sex
hormones,
oral
contraceptives
(OC)
have
been
found
to
modulate
visuospatial
verbal
abilities,
though
inconsistencies
in
literature.
Among
possible
explanations,
certain
OC
use
parameters
(progestin
androgenicity,
hormone
levels,
duration
of
use)
not
received
consistent
consideration.
Thus,
objectives
were
(1)
examine
group
differences
between
men,
combined
users,
naturally
cycling
women
(NC
women;
using
OC)
fluency,
memory
(2)
investigate
contribution
endogenous
exogenous
on
these
effects.
We
also
aimed
(3)
identify
relevant
cognitive
outcomes.
In
total,
70
53
early
follicular
(EF)
women,
43
pre-ovulatory
(PO)
47
men
underwent
tests.
Performance
was
compared
based
hormonal
milieus
(OC,
EF,
PO,
men)
users'
contraceptive
androgenicity
(anti,
low,
high).
Correlations
performance,
levels
conducted.
dampened
difference
that
typically
favors
3D
whereas
its
positively
predicted
fluency.
Androgenicity
did
predict
performance
any
task.
These
results
highlight
importance
considering
duration.
Results
support
a
role
for
Importantly,
(including
prolonged
does
impair
visuospatial,
verbal,
functions
healthy
young
sample.
Language: Английский
Sex differences persist in visuospatial mental rotation under 3D VR conditions
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(11), P. e0314270 - e0314270
Published: Nov. 25, 2024
The
classic
Vandenberg
and
Kuse
Mental
Rotations
Test
(MRT)
shows
a
male
advantage
for
visuospatial
rotation.
However,
MRTs
that
have
been
adapted
use
with
real
or
physical
objects
found
sex
differences
are
reduced
abolished.
Previous
work
has
also
suggested
virtual
3D
will
eliminate
differences,
although
this
not
demonstrated
in
purely
paradigm
without
motor
input.
In
the
present
study
we
sought
to
examine
potential
mental
rotation
using
fully-immersive
VR
adaptation
of
original
MRT
is
nature.
With
unlimited
time
23
females
males
completed
designed
approximate
stimuli.
Despite
immersive
experience
lack
pressure,
large
performance
response
accuracy,
exceeding
what
typically
reported
2D
MRTs.
No
were
observed
time.
Thus,
pure
stimuli
can
extend
VR,
even
when
there
no
constraints.
Language: Английский