Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies DOI Creative Commons

Praveen Kumar,

K.S. Pushpavalli,

Baskaran Ganesh Kumar

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 101945 - 101945

Published: Dec. 1, 2024

Language: Английский

Exploring the Potential of Gold Nanoparticles in Proton Therapy: Mechanisms, Advances, and Clinical Horizons DOI Creative Commons
Giorgio Giuseppe Carbone, Stefania Mariano, Alessandra Gabriele

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(2), P. 176 - 176

Published: Jan. 30, 2025

Proton therapy represents a groundbreaking advancement in cancer radiotherapy, leveraging the unique spatial energy distribution of protons to deliver precise, high-dose radiation tumors while sparing surrounding healthy tissues. Despite its clinical success, proton faces challenges optimizing therapeutic precision and efficacy. Recent research has highlighted potential gold nanoparticles enhance outcomes. Due their high atomic number favorable biological properties, act as radiosensitizers by amplifying generation secondary electrons reactive oxygen species upon irradiation. This enhances DNA damage tumor cells preserving Additionally, functionalization with tumor-targeting ligands offers improved precision, making more effective against broader range cancers. review synthesizes current knowledge on mechanisms nanoparticle radiosensitization, preclinical evidence, technological hurdles that must be addressed integrate this promising approach into practice, aiming advance efficacy accessibility therapy.

Language: Английский

Citations

2

Preparation, chemical characterization and determination of the antioxidant, cytotoxicity and anti-gastric properties of plant leaf aqueous extract green-synthesized gold nanoparticles DOI Creative Commons
Bowen Jiao,

Zhe Bai,

Jingyi Li

et al.

Journal of Science Advanced Materials and Devices, Journal Year: 2025, Volume and Issue: unknown, P. 100882 - 100882

Published: March 1, 2025

Language: Английский

Citations

0

Selenium, Silver, and Gold Nanoparticles: Emerging Strategies for Hepatic Oxidative Stress and Inflammation Reduction DOI Creative Commons

Karthik K Karunakar,

Binoy Varghese Cheriyan,

D. Suresh Babu

et al.

Nano TransMed, Journal Year: 2025, Volume and Issue: unknown, P. 100085 - 100085

Published: May 1, 2025

Language: Английский

Citations

0

Recent advances in nanomaterial-based brain-targeted delivery systems for glioblastoma therapy DOI

Mingyue Qu,

Quan Wang, Xinying Wang

et al.

Nanomedicine, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 17

Published: May 12, 2025

Glioblastoma (GBM) poses a formidable challenge because of its high morbidity and mortality. The therapeutic efficacy GBM is significantly hampered by the intricate blood-brain barrier (BBB) tumor (BBTB). Nanomaterial-based brain-targeted delivery systems have shown great potential for effectively delivering agents treatment overcoming limitations conventional drugs, such as poor BBB penetration, short half-life, low bioavailability. This review focuses on an in-depth analysis interplay between BBB/BBTB drug transport kinetics while analyzing innovative nanoparticle-mediated strategies enhanced treatment. Moreover, nanoparticle-based are emphasized, with particular attention given to biomimetic nanoparticles (BMNPs), whose unique advantages. current challenges, translational potential, future research directions in this rapidly evolving field comprehensively discussed, highlighting advances nanomaterial applications. aims stimulate further into systems, offering promising avenues maximizing effects gene drugs or chemotherapeutic practical

Language: Английский

Citations

0

Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies DOI Creative Commons

Praveen Kumar,

K.S. Pushpavalli,

Baskaran Ganesh Kumar

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 101945 - 101945

Published: Dec. 1, 2024

Language: Английский

Citations

1