Exploring the anti-obesity effects of kimchi through enhanced thermogenesis in differentiated T37i brown adipocytes DOI Creative Commons
Ye‐Rang Yun, Ji Eun Lee, Seongsoo Lee

et al.

Food & Nutrition Research, Journal Year: 2024, Volume and Issue: 68

Published: Aug. 29, 2024

Background: Previous research has demonstrated the anti-obesity effects of kimchi in 3T3-L1 adipocytes and mice with diet-induced obesity by assessing expression obesity-associated genes. Additionally, recent studies have identified mechanisms involving thermogenesis that support these effects. Objective: This study aims to further investigate properties kimchi, focusing on its impact thermogenic activity differentiated T37i brown adipocytes. Design: The first evaluated antioxidant potential using total capacity (TAC) ferric reducing power (FRAP) assays. Optimal differentiation conditions for were established before proceeding evaluations cell viability, intracellular triglyceride (TG) content, lipid accumulation, genes proteins related thermogenesis. Results: Kimchi maintained over 90% viability at concentrations up 1,000 μg/mL. Efficient preadipocytes was achieved a medium containing 10% calf serum, 2 nM 3,3',5-triiodo-L-thyronin (T3), 100 insulin. significantly reduced TG levels compared control group, enhanced while obesity-related Discussion: findings suggest exerts modulating pathways adipocytes, which may be partially attributed properties. Conclusions: shows promise as preventive measure against influencing metabolic associated both

Language: Английский

Mitochondrial dysfunction in drug-induced hepatic steatosis: recent findings and current concept DOI Creative Commons
Annie Borgne‐Sanchez, Bernard Fromenty

Clinics and Research in Hepatology and Gastroenterology, Journal Year: 2025, Volume and Issue: 49(3), P. 102529 - 102529

Published: Jan. 9, 2025

Language: Английский

Citations

1
Metabolic dysfunction–associated steatotic liver disease: Time to get familiar with the new name for NAFLD DOI
Maren C. Podszun

Nutrition Research, Journal Year: 2024, Volume and Issue: 126, P. 11 - 13

Published: March 18, 2024

Language: Английский

Citations

4
Exploring the anti-obesity effects of kimchi through enhanced thermogenesis in differentiated T37i brown adipocytes DOI Creative Commons
Ye‐Rang Yun, Ji Eun Lee, Seongsoo Lee

et al.

Food & Nutrition Research, Journal Year: 2024, Volume and Issue: 68

Published: Aug. 29, 2024

Background: Previous research has demonstrated the anti-obesity effects of kimchi in 3T3-L1 adipocytes and mice with diet-induced obesity by assessing expression obesity-associated genes. Additionally, recent studies have identified mechanisms involving thermogenesis that support these effects. Objective: This study aims to further investigate properties kimchi, focusing on its impact thermogenic activity differentiated T37i brown adipocytes. Design: The first evaluated antioxidant potential using total capacity (TAC) ferric reducing power (FRAP) assays. Optimal differentiation conditions for were established before proceeding evaluations cell viability, intracellular triglyceride (TG) content, lipid accumulation, genes proteins related thermogenesis. Results: Kimchi maintained over 90% viability at concentrations up 1,000 μg/mL. Efficient preadipocytes was achieved a medium containing 10% calf serum, 2 nM 3,3',5-triiodo-L-thyronin (T3), 100 insulin. significantly reduced TG levels compared control group, enhanced while obesity-related Discussion: findings suggest exerts modulating pathways adipocytes, which may be partially attributed properties. Conclusions: shows promise as preventive measure against influencing metabolic associated both

Language: Английский

Citations

0