Amino Acids,
Journal Year:
2024,
Volume and Issue:
56(1)
Published: Oct. 12, 2024
The
study
focuses
on
the
green
synthesis
of
Ag@Ag2O
nanostructures
using
Padina
algae
extract
and
functionalizing
them
with
L-tryptophan
to
enhance
their
properties
as
a
colorimetric
sensor
for
simultaneous
detection
ultra-trace
levels
thiamin
riboflavin.
are
characterized
techniques
like
XRD,
FESEM,
FTIR,
TEM,
AFM,
DLS
understand
morphology,
structure,
interactions
target
molecules.
FESEM
analysis
revealed
hierarchical
flower-like
nanostructures.
TEM
image
shows
formation
core-shell
Also,
surface
zeta
potential
spectra
illustrated
aggregated
nature
fabricated
nanocomposites
in
presence
vitamins.
is
first
report
determination
riboflavin
based
Ag@Ag2O-L-Try
partial
leas
square
(PLS).
dynamic
range
was
achieved
0.1
mol
L−1
acetate
buffer
pH
4
ratio
Ag@Ag2O:
L-try
1:1.
exhibited
two
linear
ranges
0.1-
1.0
3-350
µMol
L−
1
3.0–60
thiamin.
low
limit
1.92
0.048
obtained
thiamin,
respectively.
results
indicated
that
success
method
depends
selective
sensitive
assay
along
by
PLS
algorithm.
Hence,
proposed
technique
can
be
used
accurate
precise
vitamins
different
pharmaceutical
syrup
tablet
samples.
Cancers,
Journal Year:
2024,
Volume and Issue:
16(11), P. 2030 - 2030
Published: May 27, 2024
Immunotherapy
is
a
rapidly
advancing
field
of
research
in
the
treatment
conditions
such
as
cancer
and
autoimmunity.
Nanomaterials
can
be
designed
for
immune
system
manipulation,
with
precise
targeted
delivery
improved
immunomodulatory
efficacy.
Here,
we
elaborate
on
various
strategies
using
nanomaterials,
including
liposomes,
polymers,
inorganic
NPs,
discuss
their
detailed
design
intricacies,
mechanisms,
applications,
current
regulatory
issues.
This
type
nanomaterial
targeting
specific
cells
or
tissues
controlling
release
kinetics
could
push
technological
frontiers
provide
new
innovative
solutions
immune-related
disorders
diseases
without
off-target
effects.
These
materials
enable
interactions
cells,
thereby
enhancing
effectiveness
checkpoint
inhibitors,
vaccines,
adoptive
cell
therapies.
Moreover,
they
allow
fine-tuning
responses
while
minimizing
side
At
intersection
nanotechnology
immunology,
nanomaterial-based
platforms
have
immense
potential
to
revolutionize
patient-centered
immunotherapy
reshape
disease
management.
By
prioritizing
safety,
customization,
compliance
standards,
these
systems
make
significant
contributions
precision
medicine,
significantly
impacting
healthcare
landscape.
Review
Quantification
of
Nanomaterial
Surfaces
Harshit
Kumar
and
Mingdi
Yan
*
Department
Chemistry,
University
Massachusetts
Lowell,
1
Avenue,
MA
01854,
USA
Correspondence:
[email protected]
Received:
24
February
2025;
Revised:
3
March
Accepted:
5
Published:
10
2025
Abstract:
nanomaterial
surfaces
is
critical
in
the
design
nanomaterials
with
predictable
tailored
functions.
Nanomaterials
exhibit
unique
surface
properties,
such
as
high
surface-to-volume
ratios
tunable
chemistry,
which
govern
their
stability,
reactivity,
functions
a
wide
range
applications
including
catalysis,
drug
delivery,
bioimaging,
environmental
remediation.
However,
quantitative
analysis
challenging
due
to
inherent
heterogeneity,
affects
structure,
ligand
density
presentation.
This
mini
review
discusses
several
important
aspects
quantification,
density,
functional
groups,
reactions.
Traditional
analytical
methods,
nuclear
magnetic
resonance
(NMR)
spectroscopy,
mass
spectrometry
(MS),
UV-vis
well
emerging
techniques
that
offer
higher
spatial
resolution
sensitivity
are
discussed,
examples
given.
Roughly
1.71
billion
people
worldwide
suffer
from
large
bone
abnormalities,
which
are
the
primary
cause
of
disability.
Traditional
grafting
procedures
have
several
drawbacks
that
impair
their
therapeutic
efficacy
and
restrict
use
in
clinical
settings.
A
great
deal
work
has
been
done
to
create
fresh,
more
potent
strategies.
Under
these
circumstances,
a
crucial
technique
for
regeneration
major
lesions
emerged:
tissue
engineering
(BTE).
BTE
involves
biomaterials
can
imitate
natural
design
bone.
To
yet,
no
biological
material
able
fully
meet
parameters
perfect
implantable
material,
even
though
varieties
created
investigated
regeneration.
Against
this
backdrop,
researchers
focused
interest
over
past
few
years
on
subject
nanotechnology
nanostructures
regenerative
medicine.
The
ability
nanoengineered
particles
overcome
current
constraints
strategies─such
as
decreased
cell
proliferation
differentiation,
insufficient
mechanical
strength
materials,
production
extrinsic
factors
required
effective
osteogenesis
revolutionized
field
engineering.
effects
nanoparticles
characteristics
application
materials
main
topics
our
review,
summarizes
most
recent
vitro
vivo
research
context
BTE.
Journal of Functional Biomaterials,
Journal Year:
2025,
Volume and Issue:
16(3), P. 108 - 108
Published: March 19, 2025
Loss
of
implant
function
is
a
common
complication
in
orthopaedic
and
dental
surgery.
Among
the
primary
causes
failure
are
peri-implant
infections
which
often
result
removal.
This
study
demonstrates
development
new
antimicrobial
titanium
coating
with
ZnO
nanoparticles
various
sizes
morphologies
immobilised
poly(allylamine
hydrochloride)
alginate
multilayers,
combined
epitaxially
grown
vaterite
crystals.
The
coated
samples
were
characterised
methods
(FTIR,
XRD,
SEM)
surface
properties
evaluated
via
water
contact
angle
charge
measurements.
Zinc
ion
release
was
quantified
using
ICP-MS.
efficacy
coatings
tested
against
Staphylococcus
aureus,
epidermidis,
Candida
albicans
while
biocompatibility
preosteoblast
cells
(MC3T3-E1).
Results
demonstrated
successful
preparation
calcium
carbonate/ZnO
composite
on
surfaces.
Zn
ions
released
from
dramatically
influenced
morphology
where
flower-like
observed.
surfaces
exhibited
robust
activity,
achieving
over
90%
microbial
viability
reduction
for
albicans.
Importantly,
Zn2+
concentrations
remained
below
cytotoxicity
limit
MC3T3-E1
cells,
showing
potential
safe
effective
applications.
Photochemistry and Photobiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 1, 2025
Despite
advancements
made
in
treatment
options,
cancer
continues
to
be
one
of
the
leading
causes
death
worldwide.
Photodynamic
therapy
(PDT)
has
gained
attention
as
a
minimally
invasive
and
highly
selective
option
for
cancer.
However,
challenges
due
hydrophobicity
photosensitizers
their
poor
tumor
selectivity
have
limited
use
therapy.
Recent
developments
nanotechnology,
particularly
gold
nanoparticles
(AuNPs),
help
overcome
these
challenges.
AuNPs
provide
stable
biocompatible
platform
deliver
photosensitizers,
improving
solubility,
stability,
ability
target
tumors
while
reducing
side
effects.
Functionalized
take
advantage
mechanisms
like
enhanced
permeability
retention
(EPR)
effect
active
targeting,
reactive
oxygen
species
(ROS)
production
overall
therapeutic
efficacy.
This
review
explores
innovations
AuNP-based
PDT
systems,
including
ligand-functionalized
nanoparticles,
bioresponsive
coatings,
theranostic
approaches
that
combine
imaging
with
By
delving
into
important
aspects
synthesis,
characterization,
functionalization,
we
show
how
improve
delivery
performance
photosensitizers.
For
instance,
systems
functionalized
prostate-specific
membrane
antigen
(PSMA)
shown
increased
precision
efficacy
vivo.
These
are
paving
way
more
targeted
safer
treatments,
establishing
promising
approach
developing
effective
oncological
therapies
greater
fewer
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 26, 2025
Abstract
Supraparticles
(SPs)
with
unique
properties
are
emerging
as
versatile
platforms
for
applications
in
catalysis,
photonics,
and
medicine.
However,
the
synthesis
of
novel
SPs
complex
internal
structures
remains
a
challenge.
Self‐Assembled
Multilayered
(SAMS)
presented
here
composed
concentric
lamellar
spherical
made
from
metallic
nanoparticles,
formed
synergistic
three‐way
interaction
phenomenon
between
gold
lipidoid,
gelatin,
exhibiting
interlayer
spacing
3.5
±
0.2
nm
within
self‐limited
156.8
56.6
diameter.
The
formation
is
critically
influenced
by
both
physical
(including
nanoparticle
size,
lipidoid
chain
length)
chemical
factors
elemental
composition,
cap,
organic
material),
which
collectively
modulate
surface
chemistry
hydrophobicity,
affecting
interparticle
interactions.
SAMS
can
efficiently
deliver
labile
payloads
such
siRNA,
achieving
dose‐dependent
silencing
vivo,
while
also
showing
potential
mRNA.
This
work
not
only
advances
field
SP
design
introducing
new
structure
but
demonstrates
its
nanomedicine.
