Life at new extremes: Integrating stress physiology and the bio‐exposome in the Anthropocene DOI Creative Commons
David Costantini, Simone Messina, Manrico Sebastiano

et al.

Annals of the New York Academy of Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

Abstract Conventional physiological research has focused on elucidating the endogenous mechanisms that underly adaptations of species to life in extreme habitats, such as polar regions or deserts. In this review article, we argue even habitats are not considered extremes facing unpredictable, rapid, and strong modifications due human activities expose animals novel conditions. Thus, these can offer insight role plasticity driving their resilience adaptation. To end, discuss how stress physiology (with a particular focus oxidative stress) central mediating interaction between exposome (measure all environmental exposures an individual lifetime) cellular processes (bio‐exposome) contexts relevant anthropogenic changes habitat We also provide concrete examples relationship bio‐exposome free‐living animals, be health. Finally, propose future directions integrating One Health framework achieve holistic understanding proximate underlying responses changes.

Language: Английский

Life at new extremes: Integrating stress physiology and the bio‐exposome in the Anthropocene DOI Creative Commons
David Costantini, Simone Messina, Manrico Sebastiano

et al.

Annals of the New York Academy of Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

Abstract Conventional physiological research has focused on elucidating the endogenous mechanisms that underly adaptations of species to life in extreme habitats, such as polar regions or deserts. In this review article, we argue even habitats are not considered extremes facing unpredictable, rapid, and strong modifications due human activities expose animals novel conditions. Thus, these can offer insight role plasticity driving their resilience adaptation. To end, discuss how stress physiology (with a particular focus oxidative stress) central mediating interaction between exposome (measure all environmental exposures an individual lifetime) cellular processes (bio‐exposome) contexts relevant anthropogenic changes habitat We also provide concrete examples relationship bio‐exposome free‐living animals, be health. Finally, propose future directions integrating One Health framework achieve holistic understanding proximate underlying responses changes.

Language: Английский

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