Biomedical Optics Express,
Journal Year:
2022,
Volume and Issue:
14(2), P. 489 - 489
Published: Dec. 15, 2022
Ptychography
is
an
enabling
microscopy
technique
for
both
fundamental
and
applied
sciences.
In
the
past
decade,
it
has
become
indispensable
imaging
tool
in
most
X-ray
synchrotrons
national
laboratories
worldwide.
However,
ptychography's
limited
resolution
throughput
visible
light
regime
have
prevented
its
wide
adoption
biomedical
research.
Recent
developments
this
resolved
these
issues
offer
turnkey
solutions
high-throughput
optical
with
minimum
hardware
modifications.
The
demonstrated
now
greater
than
that
of
a
high-end
whole
slide
scanner.
review,
we
discuss
basic
principle
ptychography
summarize
main
milestones
development.
Different
ptychographic
implementations
are
categorized
into
four
groups
based
on
their
lensless/lens-based
configurations
coded-illumination/coded-detection
operations.
We
also
highlight
related
applications,
including
digital
pathology,
drug
screening,
urinalysis,
blood
analysis,
cytometric
rare
cell
culture
monitoring,
tissue
2D
3D,
polarimetric
among
others.
imaging,
currently
early
stages,
will
continue
to
improve
performance
expand
applications.
conclude
review
article
by
pointing
out
several
directions
future
Abstract
With
the
advances
in
scientific
foundations
and
technological
implementations,
optical
metrology
has
become
versatile
problem-solving
backbones
manufacturing,
fundamental
research,
engineering
applications,
such
as
quality
control,
nondestructive
testing,
experimental
mechanics,
biomedicine.
In
recent
years,
deep
learning,
a
subfield
of
machine
is
emerging
powerful
tool
to
address
problems
by
learning
from
data,
largely
driven
availability
massive
datasets,
enhanced
computational
power,
fast
data
storage,
novel
training
algorithms
for
neural
network.
It
currently
promoting
increased
interests
gaining
extensive
attention
its
utilization
field
metrology.
Unlike
traditional
“physics-based”
approach,
deep-learning-enabled
kind
“data-driven”
which
already
provided
numerous
alternative
solutions
many
challenging
this
with
better
performances.
review,
we
present
an
overview
current
status
latest
progress
deep-learning
technologies
We
first
briefly
introduce
both
image-processing
basic
concepts
followed
comprehensive
review
applications
various
tasks,
fringe
denoising,
phase
retrieval,
unwrapping,
subset
correlation,
error
compensation.
The
open
challenges
faced
approach
are
then
discussed.
Finally,
directions
future
research
outlined.
Journal of Materials Research and Technology,
Journal Year:
2021,
Volume and Issue:
12, P. 1649 - 1672
Published: March 27, 2021
A
sensor
is
a
tool
used
to
directly
measure
the
test
compound
(analyte)
in
sample.
Ideally,
such
device
capable
of
continuous
and
reversible
response
should
not
damage
Nanosensor
refers
system
which
at
least
one
nanostructures
detect
gases,
chemicals,
biological
agents,
electric
fields,
light,
heat,
etc.
its
construction.
The
use
nanomaterials
significantly
increases
sensitivity
system.
In
biosensors,
part
attach
analyte
specifically
it
element
(such
as
DNA
strand,
antibody,
enzyme,
whole
cell).
"Nano
Biosensors"
series
reviews
various
types
biosensors
biochips
(including
an
array
biosensors),
emphasizing
role
nanostructures,
developed
for
medical
applications.
Nano
Biosensors
Electrochemical
sensors
are
that
diagnostic
component
electrode
transducer.
these
systems
usually
done
fill
gap
between
converter
bioreceptor,
nanoscale.
Given
nature
biomaterial
detection
process,
electrochemical
divided
into
catalytic
propulsion.
Common
techniques
common
include
potentiometric,
chronometry,
voltammetry,
impedance
measurement,
field
effect
transistor
(FET).
Simultaneous
advantages
has
led
emergence
with
high
decomposition
power.
Various
including
nanoparticles,
nanotubes
nanowires,
nanopores,
self-adhesive
monolayers
nanocomposites
can
be
improve
performance
efficiency
their
structure.
ACS Nano,
Journal Year:
2022,
Volume and Issue:
16(8), P. 11516 - 11544
Published: Aug. 2, 2022
Quantitative
phase
imaging
(QPI)
is
a
label-free,
wide-field
microscopy
approach
with
significant
opportunities
for
biomedical
applications.
QPI
uses
the
natural
shift
of
light
as
it
passes
through
transparent
object,
such
mammalian
cell,
to
quantify
biomass
distribution
and
spatial
temporal
changes
in
biomass.
Reported
cell
studies
more
than
60
years
ago,
ongoing
advances
hardware
software
are
leading
numerous
applications
biology,
dramatic
expansion
utility
over
past
two
decades.
Today,
investigations
size,
morphology,
behavior,
cellular
viscoelasticity,
drug
efficacy,
accumulation
turnover,
transport
mechanics
supporting
development,
physiology,
neural
activity,
cancer,
additional
physiological
processes
diseases.
Here,
we
review
field
biology
starting
underlying
principles,
followed
by
discussion
technical
approaches
currently
available
or
being
developed,
end
an
examination
breadth
use
under
development.
We
comment
on
strengths
shortcomings
deployment
key
contexts
conclude
emerging
challenges
based
combining
other
methodologies
that
expand
scope
even
further.
PhotoniX,
Journal Year:
2022,
Volume and Issue:
3(1)
Published: Jan. 28, 2022
Abstract
Accurate
depiction
of
waves
in
temporal
and
spatial
is
essential
to
the
investigation
interactions
between
physical
objects
waves.
Digital
holography
(DH)
can
perform
quantitative
analysis
wave–matter
interactions.
Full
detector-bandwidth
reconstruction
be
realized
based
on
in-line
DH.
But
overlapping
twin
images
strongly
prevents
analysis.
For
off-axis
DH,
object
wave
detector
bandwidth
need
satisfy
certain
conditions
accurately.
Here,
we
present
a
reliable
approach
involving
coupled
configuration
for
combining
two
holograms
one
hologram,
using
rapidly
converging
iterative
procedure
two-plane
phase
retrieval
(TwPCPR)
method.
It
realizes
fast-convergence
holographic
calculation
High-resolution
full-field
by
exploiting
full
are
demonstrated
complex-amplitude
reconstruction.
Off-axis
optimization
provides
an
effective
initial
guess
avoid
stagnation
minimize
required
measurements
multi-plane
retrieval.
The
proposed
strategy
works
well
more
extended
samples
without
any
prior
assumptions
including
support,
non-negative,
sparse
constraints,
etc.
helps
enhance
empower
applications
wavefront
sensing,
computational
microscopy
biological
tissue
Phase
recovery
(PR)
refers
to
calculating
the
phase
of
light
field
from
its
intensity
measurements.
As
exemplified
quantitative
imaging
and
coherent
diffraction
adaptive
optics,
PR
is
essential
for
reconstructing
refractive
index
distribution
or
topography
an
object
correcting
aberration
system.
In
recent
years,
deep
learning
(DL),
often
implemented
through
neural
networks,
has
provided
unprecedented
support
computational
imaging,
leading
more
efficient
solutions
various
problems.
this
review,
we
first
briefly
introduce
conventional
methods
PR.
Then,
review
how
DL
provides
following
three
stages,
namely,
pre-processing,
in-processing,
post-processing.
We
also
used
in
image
processing.
Finally,
summarize
work
provide
outlook
on
better
use
improve
reliability
efficiency
Furthermore,
present
a
live-updating
resource
(
https://github.com/kqwang/phase-recovery
)
readers
learn
about
Deleted Journal,
Journal Year:
2023,
Volume and Issue:
4(1), P. 1 - 1
Published: Jan. 1, 2023
Holography
provides
access
to
the
optical
phase.
The
emerging
compressive
phase
retrieval
approach
can
achieve
in-line
holographic
imaging
beyond
information-theoretic
limit
or
even
from
a
single
shot
by
exploring
signal
priors.
However,
iterative
projection
methods
based
on
physical
knowledge
of
wavefield
suffer
poor
quality,
whereas
regularization
techniques
sacrifice
robustness
for
fidelity.
In
this
work,
we
present
unified
framework
holography
that
encapsulates
unique
advantages
both
constraints
and
sparsity
particular,
constrained
complex
total
variation
(CCTV)
regularizer
is
introduced
explores
well-known
absorption
support
together
with
in
gradient
domain,
enabling
practical
high-quality
intensity
image.
We
developed
efficient
solvers
proximal
method
non-smooth
regularized
inverse
problem
corresponding
denoising
subproblem.
Theoretical
analyses
further
guarantee
convergence
algorithms
prespecified
parameters,
obviating
need
manual
parameter
tuning.
As
simulated
experiments
demonstrate,
proposed
CCTV
model
characterize
natural
scenes
while
utilizing
physically
tractable
quality
enhancement.
This
new
be
extended,
minor
adjustments,
various
configurations,
sparsifying
operators,
knowledge.
It
may
cast
light
theoretical
empirical
studies.
Abstract
Label‐free
super‐resolution
(LFSR)
imaging
relies
on
light‐scattering
processes
in
nanoscale
objects
without
a
need
for
fluorescent
(FL)
staining
required
super‐resolved
FL
microscopy.
The
objectives
of
this
Roadmap
are
to
present
comprehensive
vision
the
developments,
state‐of‐the‐art
field,
and
discuss
resolution
boundaries
hurdles
that
be
overcome
break
classical
diffraction
limit
label‐free
imaging.
scope
spans
from
advanced
interference
detection
techniques,
where
diffraction‐limited
lateral
is
combined
with
unsurpassed
axial
temporal
resolution,
techniques
true
capability
based
understanding
as
an
information
science
problem,
using
novel
structured
illumination,
near‐field
scanning,
nonlinear
optics
approaches,
designing
superlenses
nanoplasmonics,
metamaterials,
transformation
optics,
microsphere‐assisted
approaches.
To
end,
brings
under
same
umbrella
researchers
physics
biomedical
communities
which
such
studies
have
often
been
developing
separately.
ultimate
intent
paper
create
current
future
developments
LFSR
its
physical
mechanisms
great
opening
series
articles
field.
Abstract
In
1948,
Dennis
Gabor
proposed
the
concept
of
holography,
providing
a
pioneering
solution
to
quantitative
description
optical
wavefront.
After
75
years
development,
holographic
imaging
has
become
powerful
tool
for
wavefront
measurement
and
phase
imaging.
The
emergence
this
technology
given
fresh
energy
physics,
biology,
materials
science.
Digital
holography
(DH)
possesses
advantages
wide-field,
non-contact,
precise,
dynamic
capability
complex-waves.
DH
unique
capabilities
propagation
fields
by
measuring
light
scattering
with
information.
It
offers
visualization
refractive
index
thickness
distribution
weak
absorption
samples,
which
plays
vital
role
in
pathophysiology
various
diseases
characterization
materials.
provides
possibility
bridge
gap
between
disciplines.
is
described
complex
amplitude.
complex-value
complex-domain
reconstructed
from
intensity-value
camera
real-domain.
Here,
we
regard
process
recording
reconstruction
as
transformation
real-domain,
discuss
mathematics
physical
principles
reconstruction.
We
review
underlying
principles,
technical
approaches,
breadth
applications.
conclude
emerging
challenges
opportunities
based
on
combining
other
methodologies
that
expand
scope
utility
even
further.
multidisciplinary
nature
brings
application
experts
together
label-free
cell
analytical
chemistry,
clinical
sciences,
sensing,
semiconductor
production.