IA´ Tools for the development of investigative skills DOI
Mayra Alejandra Gaviria Alvarado

LatIA, Journal Year: 2023, Volume and Issue: 1, P. 17 - 17

Published: Nov. 30, 2023

This article explores how the artificial intelligence (IA) it is transforming education in natural sciences by means of strategies pedagogic innovators. The IA allows learning personalization, adjusting content and rhythm to individual necessities students, what improves understanding retention complex concepts significantly. Also, use simulations virtual models believe interactive visual environments, enriching educational experience. These tools also foment development critical creative skills, promoting a more active collaborative approach resolution scientific problems. On whole, these not only improve effectiveness learning, but rather they prepare students face challenges XXI century with solid base science technology.

Language: Английский

Non-invasive optoacoustic imaging of glycogen-storage and muscle degeneration in late-onset Pompe disease DOI Creative Commons

Lina Tan,

Jana Zschüntzsch,

Stefanie Meyer

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Sept. 8, 2024

Abstract Pompe disease (PD) is a rare autosomal recessive glycogen storage disorder that causes proximal muscle weakness and loss of respiratory function. While enzyme replacement therapy (ERT) the only effective treatment, biomarkers for monitoring are scarce. Following ex vivo biomarker validation in phantom studies, we apply multispectral optoacoustic tomography (MSOT), laser- ultrasound-based non-invasive imaging approach, clinical trial (NCT05083806) to image biceps muscles 10 late-onset PD (LOPD) patients matched healthy controls. MSOT compared with magnetic resonance (MRI), ultrasound, spirometry, testing quality life scores. Next, results validated an independent LOPD patient cohort from second site. Our study demonstrates enables subcellular pathology increases glycogen/water, collagen lipid signals, providing higher sensitivity detecting degeneration than current methods. This translational approach suggests implementation complex care these patients.

Language: Английский

Citations

2

In vivo multi-scale clinical photoacoustic imaging for analysis of skin vasculature and pigmentation: a comparative review DOI
Junho Ahn, Minseong Kim, Chulhong Kim

et al.

Advanced imaging., Journal Year: 2024, Volume and Issue: 1(3), P. 032002 - 032002

Published: Jan. 1, 2024

Language: Английский

Citations

1

Multispectral Imaging-Based System for Detecting Tissue Oxygen Saturation With Wound Segmentation for Monitoring Wound Healing DOI Creative Commons
Chih‐Lung Lin, Meng-Hsuan Wu, Yuan-Hao Ho

et al.

IEEE Journal of Translational Engineering in Health and Medicine, Journal Year: 2024, Volume and Issue: 12, P. 468 - 479

Published: Jan. 1, 2024

Objective: Blood circulation is an important indicator of wound healing. In this study, a tissue oxygen saturation detecting (TOSD) system that based on multispectral imaging (MSI) proposed to quantify the degree (StO 2 ) in cutaneous tissues. Methods: A segmentation algorithm used segment automatically and skin areas, eliminating need for manual labeling applying adaptive optics. Animal experiments were conducted six mice which they observed seven times, once every two days. The TOSD illuminated tissues with wavelengths light - red (λ = 660 nm) near-infrared 880 nm), StO levels calculated using images captured monochrome camera. ResNet34-based U-Net was integrated computer vision techniques improve its performance. Results: revealed achieved Dice score 93.49%. determined varied significantly among phases Changes detected before laser speckle contrast (LSCI) changes blood flux. Moreover, statistical features extracted from LSCI utilized principal component analysis (PCA) visualize different healing phases. average silhouette coefficients (ResNet34-based U-Net) 0.2890 0.0194, respectively. Conclusion: By segmentation, accurately distinguished. This method can support medical personnel conducting precise assessments.

Language: Английский

Citations

1

Ultrasound-guided needle tracking with deep learning: A novel approach with photoacoustic ground truth DOI Creative Commons
Hui Xie, Praveenbalaji Rajendran, Tong Ling

et al.

Photoacoustics, Journal Year: 2023, Volume and Issue: 34, P. 100575 - 100575

Published: Nov. 29, 2023

Accurate needle guidance is crucial for safe and effective clinical diagnosis treatment procedures. Conventional ultrasound (US)-guided insertion often encounters challenges in consistency precisely visualizing the needle, necessitating development of reliable methods to track needle. As a powerful tool image processing, deep learning has shown promise enhancing visibility US images, although its dependence on manual annotation or simulated data as ground truth can lead potential bias difficulties generalizing real images. Photoacoustic (PA) imaging demonstrated capability high-contrast visualization. In this study, we explore PA network training without need expert annotation. Our (UIU-Net), trained ex vivo tissue datasets, remarkable precision localizing needles within The evaluation segmentation performance extends across previously unseen human (collected from an open-source repository). Specifically, data, Modified Hausdorff Distance (MHD) value stands at approximately 3.73, targeting error around 2.03, indicating strong similarity small orientation deviation between predicted actual location. A key advantage our method applicability beyond images captured specific systems, extending other systems.

Language: Английский

Citations

3

IA´ Tools for the development of investigative skills DOI
Mayra Alejandra Gaviria Alvarado

LatIA, Journal Year: 2023, Volume and Issue: 1, P. 17 - 17

Published: Nov. 30, 2023

This article explores how the artificial intelligence (IA) it is transforming education in natural sciences by means of strategies pedagogic innovators. The IA allows learning personalization, adjusting content and rhythm to individual necessities students, what improves understanding retention complex concepts significantly. Also, use simulations virtual models believe interactive visual environments, enriching educational experience. These tools also foment development critical creative skills, promoting a more active collaborative approach resolution scientific problems. On whole, these not only improve effectiveness learning, but rather they prepare students face challenges XXI century with solid base science technology.

Language: Английский

Citations

3