Simultaneous Photoacoustic and Laser‐Induced Ultrasound Imaging of Animals and Humans via a Semi‐Transparent Ultrasound Transducer DOI Creative Commons

Bjarne Perleberg,

Sangmin Lee, Preeti Malik

et al.

Laser & Photonics Review, Journal Year: 2025, Volume and Issue: unknown

Published: May 21, 2025

Abstract Combined photoacoustic (PA) and ultrasound (US) imaging, a promising modality for preclinical clinical studies, can provide anatomical, physiological, molecular information about biological tissues. However, common implementations of US imaging require an external pulser to transmit waves, which makes integrated PA/US systems relatively complicated suboptimal. Here, without using pulser, simultaneous PA laser‐induced (LUS) is demonstrated through semi‐transparent transducer (sTUT). Some portion excitation laser energy converted waves when the beam passes sTUT, transmitting focused targets. The other light directly delivered tissues generate signals. This bimodal approach not only eliminates need electrical‐pulser but also allows sTUT be incorporated with preamplifier increase signal‐to‐noise ratio. Further, light, compact easily as part handheld PA/LUS system in vivo studies small animals humans. it photoacoustically ultrasonically visualize different structures functions human skin structures. simplified microscopic has great potential broadband studies.

Language: Английский

Simultaneous Photoacoustic and Laser‐Induced Ultrasound Imaging of Animals and Humans via a Semi‐Transparent Ultrasound Transducer DOI Creative Commons

Bjarne Perleberg,

Sangmin Lee, Preeti Malik

et al.

Laser & Photonics Review, Journal Year: 2025, Volume and Issue: unknown

Published: May 21, 2025

Abstract Combined photoacoustic (PA) and ultrasound (US) imaging, a promising modality for preclinical clinical studies, can provide anatomical, physiological, molecular information about biological tissues. However, common implementations of US imaging require an external pulser to transmit waves, which makes integrated PA/US systems relatively complicated suboptimal. Here, without using pulser, simultaneous PA laser‐induced (LUS) is demonstrated through semi‐transparent transducer (sTUT). Some portion excitation laser energy converted waves when the beam passes sTUT, transmitting focused targets. The other light directly delivered tissues generate signals. This bimodal approach not only eliminates need electrical‐pulser but also allows sTUT be incorporated with preamplifier increase signal‐to‐noise ratio. Further, light, compact easily as part handheld PA/LUS system in vivo studies small animals humans. it photoacoustically ultrasonically visualize different structures functions human skin structures. simplified microscopic has great potential broadband studies.

Language: Английский

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