Movement Disorders and Smart Wrist Devices: A Comprehensive Study
Sensors,
Journal Year:
2025,
Volume and Issue:
25(1), P. 266 - 266
Published: Jan. 5, 2025
In
the
medical
field,
there
are
several
very
different
movement
disorders,
such
as
tremors,
Parkinson’s
disease,
or
Huntington’s
disease.
A
wide
range
of
motor
and
non-motor
symptoms
characterizes
them.
It
is
evident
that
in
modern
era,
use
smart
wrist
devices,
smartwatches,
wristbands,
bracelets
spreading
among
all
categories
people.
This
diffusion
justified
by
limited
costs,
ease
use,
less
invasiveness
(and
consequently
greater
acceptability)
than
other
types
sensors
used
for
health
status
monitoring.
systematic
review
aims
to
synthesize
research
studies
using
devices
a
specific
class
disorders.
Following
PRISMA-S
guidelines,
130
were
selected
analyzed.
For
each
study,
information
provided
relating
smartwatch/wristband/bracelet
model
(whether
it
commercial
not),
number
end-users
involved
experimentation
stage,
finally
characteristics
benchmark
dataset
possibly
testing.
Moreover,
some
articles
also
reported
type
raw
data
extracted
from
device,
implemented
designed
algorithmic
pipeline,
classification
methodology.
turned
out
most
have
been
published
last
ten
years,
showing
growing
interest
scientific
community.
The
mainly
investigate
relationship
between
Epilepsy
seizure
detection
topics
interest,
while
few
papers
analyzing
gait
Disease,
ataxia,
Tourette
Syndrome.
However,
results
this
highlight
difficulties
still
present
identified
despite
advantages
these
technologies
could
bring
dissemination
low-cost
solutions
usable
directly
within
living
environments
without
need
caregivers
personnel.
Language: Английский
Considerations on How to Prevent Parkinson’s Disease Through Exercise
Journal of Parkinson s Disease,
Journal Year:
2024,
Volume and Issue:
14(s2), P. S395 - S406
Published: July 19, 2024
The
increasing
prevalence
of
people
with
Parkinson’s
disease
(PD)
necessitates
a
high
priority
for
finding
interventions
to
delay
or
even
prevent
the
onset
PD.
There
is
converging
evidence
that
exercise
may
exert
disease-modifying
effects
in
clinically
manifest
PD,
but
whether
also
has
preventive
effect
able
modify
progression
pathology
prodromal
phase
PD
unclear.
Here
we
provide
some
considerations
on
design
trials
aim
through
exercise.
First,
discuss
who
could
benefit
from
exercise,
and
potential
exercise-related
risks.
Second,
what
specific
components
mediate
putative
effects.
Third,
address
how
methodological
challenges
such
as
blinding,
adherence
remote
monitoring
be
handled
can
measure
efficacy
modifier
course
We
hope
these
help
designing
prevention
persons
at
risk
developing
Language: Английский
Editorial: Effectiveness of exercise and diet on movement disorders
Frontiers in Aging Neuroscience,
Journal Year:
2025,
Volume and Issue:
17
Published: Feb. 20, 2025
Movement
disorders
(MD)
are
complex
neurological
conditions
affecting
the
amount
and
fluidity
of
available
movement
control.
These
have
multiple
possible
causes
do
not
fit
into
other
established
diagnostic
categories.
MD,
which
include
such
as
Parkinson's
disease
(PD),
system
atrophy
(MSA),
progressive
supranuclear
palsy
(PSP),
corticobasal
syndrome,
cervical
dystonia
others,
a
significant
impact
on
quality
life
individuals
worldwide
but
prevalence
incidence
rates
vary
by
condition
geographical
area
(Abbas
et
al.,
2018).The
MD
increase
with
age
(Wenning
2005),
essential
tremor
PD
being
more
common
(Luo
2025;Song
2021).
The
spectrum
impairments
is
very
broad,
bradykinesia
or
hypokinesia
at
one
end
tremor,
dystonia,
chorea,
stereotypies,
athetosis,
myoclonus
dyskinesias
(Jankovic
&
Lang,
In
hyperkinetic
disorders,
abnormal
involuntary
movements
may
occur
rest
during
voluntary
be
rhythmic
(e.g.
tremor),
sustained
dystonia)
irregular
chorea
myoclonus)
(Arabia
2022;Novellino
2009;Perju-Dumbrava
Kempster,
2020;Stephen
2023).
On
hand,
hypokinetic
characterized
reduction
in
and/or
difficulty
initiating
often
no
identifiable
cause
referred
to
primary
opposed
secondary
causes,
infection
(Desai
2024;Divya
2024).
Both
groups
present
both
motor
non-motor
symptoms
present,
diagnosis
management
these
challenging
task
for
healthcare
professionals,
especially
knowing
that
criteria
frameworks
diverse
(Mestre
2023).For
complete
assessment,
historical
-family
personal,
including
birth
history
early
developmental
abnormalities
-and
clinical
features
obtained
physical
examination
laboratory
testing
paramount
importance
addition,
technologysuch
apps
wearables
-has
shown
promising
results
increasing
objectivity
assessment
(Caroppo
2025;Vanmechelen
2023;Willemse
2024)
proper
validation
studies
needed
confidence
clinicians
implementing
solutions
practice.The
people
also
challenging,
they
experience
difficulties
mobility,
balance
activities
daily
living,
symptoms,
cognitive
changes
psychiatric
manifest
progresses.
Given
nature
conditions,
palliative
approach
can
help
throughout
course
long-term
(Miyasaki
2022).
Pharmacological
therapy
cornerstone
(Jankovic,
2009;Pirker
2023)
approaches,
gene
Kim
Chang,
2024),
becoming
increasingly
relevant.
Moreover,
evidence
highlights
therapeutic
potential
non-pharmacological
approaches
exercise
therapy,
nutrition-based
interventions,
reduce
progression
severity
(Ferrazzoli
2022;Lister,
2020;Macías-García
2024;Zhang
2024).The
aim
this
Research
Topic
was
share
ideas,
opinions,
comments
latest
research
providing
mechanisms
safety
exercise-and
diet-induced
neuroprotective,
anti-inflammatory
immunological)
strategies
improve
adherence
empowerment
different
contexts,
gaps
still
need
filled
high
evidence.
This
includes
eight
papers
address
questions.
Four
original
four
literature
reviews
deepen
our
understanding
interventions
their
practical
applications.
Among
contributions,
Mateus
Caldas
reported
three
cases
palsy,
describing
benefits
physiotherapy
through
improving
functionality
life;
cross-sectional
study
strengthened
knowledge
association
between
function
health-related
(Ge
al.),
insights
aspects
should
tackled
professionals;
Yaqoob
al.
demonstrated
an
accelerometer-based
gait
sit-to-stand
tasks
has
good
agreement
direct
observation;
Taloria
presented
non-randomized
demonstrating
multimodal
(exercise,
speech
cognitive)
training
programme
PD.The
systematic
published
provided
valuable
certainty
existing
guide
working
well
future
area.
Homann
showed
randomised
controlled
trials
analysing
Vitamin
D
supplementation
later
show
benefit
limited
number
MD.
However,
mainly
led
authors
conclude
there
clear
further
For
robust
provide
researchers.
Yuan
network
meta-analysis
identifying
specific
modalities
dosages
significantly
patients
PD,
aquatic
emerging
most
effective
modality.
findings
partially
challenged
Liu
who
concluded
hydrotherapy
had
positive
maintenance
effect
population,
effects
function,
life.
Finally,
Cui
highlighted
ACSM
recommendations
when
prescribing
higher
compliance
were
beneficial
balance,
population.Taking
account
contributions
Topic,
body
diet
been
strengthened.
less
dietary
interventions.As
expected
increase,
needed.
Diet
key
components
multidisciplinary
rehabilitation
strategy
lacking,
particularly
interventions.
contributes
growing
supporting
We
hope
will
inspire
inform
practice
affected
conditions.
Language: Английский
Smartphone Application for Spastic Ataxias Cross-Sectional Validation of a Newly Developed Smartphone App for Remote Monitoring in Spastic Ataxias
The Cerebellum,
Journal Year:
2025,
Volume and Issue:
24(3)
Published: March 24, 2025
Abstract
Effective
trial-planning
in
Spastic
ataxias
(SPAX)
is
impeded
by
the
absence
of
validated
outcome
measures
for
detecting
longitudinal
changes.
Digital
show
promise,
demonstrating
sensitivity
to
disease
severity
changes
ataxia
and
strong
correlations
with
clinical
scales.
The
objective
this
study
was
develop
a
smartphone
application
SPAX
(SPAX-app)
obtain
valid
digital
use
trials.
app
contains
four
tasks
assessing
gait,
standing
balance
(stance),
finger
hand
movements.
We
carried
out
validation
22
patients
10
controls.
Subjects
performed
three
times
during
one
visit.
In
parallel,
we
Ambulatory
Parkinson’s
Disease
Monitoring
(APDM)
sensor
recordings,
Q-motor
upper
limb
assessment,
Scale
Assessment
Rating
Ataxia
(SARA).
Significant
were
found
between
SPAX-app
APDM
or
step
time
(
r
=
0.91),
all
stance
0.51–0.87)
duration
alternation
0.64).
No
significant
variability
(e.g.
standard
deviation
time).
All
SPAX-app,
except
stance,
can
discriminate
from
controls
moderate
high
test-retest
reliability
(ICC
0.67–0.97).
SARA
0.70),
inter-onset
interval
tapping
0.57),
0.65).
task
did
not
SARA.
With
present
set
potential
Longitudinal
studies
are
needed
evaluate
whether
these
track
progression.
Language: Английский
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies
Basic & Clinical Pharmacology & Toxicology,
Journal Year:
2024,
Volume and Issue:
135(3), P. 271 - 284
Published: July 8, 2024
Parkinson's
disease
(PD)
is
a
common
neurodegenerative
disorder
characterized
by
progressive
loss
of
dopamine
neurons
and
aberrant
deposits
alpha-synuclein
(α-syn)
in
the
brain.
The
symptomatic
treatment
started
after
onset
motor
manifestations
late
stage
disease.
Preclinical
studies
with
neurotrophic
factors
(NTFs)
show
promising
results
disease-modifying
neuroprotective
or
even
neurorestorative
effects.
Four
NTFs
have
entered
phase
I-II
clinical
trials
inconclusive
outcomes.
This
not
surprising
because
preclinical
evidence
from
acute
early-stage
models,
but
included
advanced
PD
patients.
To
conclude
value
NTF
therapies,
should
be
performed
patients
prodromal
symptoms,
that
is,
before
manifestations.
In
this
review,
we
summarize
currently
available
diagnostic
prognostic
biomarkers
could
help
identify
at-risk
benefiting
therapies.
Focus
on
biochemical
imaging
biomarkers,
also
other
modalities
are
discussed.
Neuroimaging
most
important
tool
today,
α-syn
yet
viable.
Modern
techniques
allow
measuring
various
forms
cerebrospinal
fluid,
blood,
saliva,
skin.
Digital
artificial
intelligence
offer
new
means
for
early
diagnosis
longitudinal
follow-up
degenerative
brain
diseases.
Language: Английский
Deep learning of Parkinson's movement from video, without human-defined measures
Journal of the Neurological Sciences,
Journal Year:
2024,
Volume and Issue:
463, P. 123089 - 123089
Published: June 10, 2024
Language: Английский
New chronic inflammatory demyelinating polyneuropathy/Guillain–Barré syndrome guidelines – impact on clinical practise
Current Opinion in Neurology,
Journal Year:
2024,
Volume and Issue:
37(5), P. 455 - 460
Published: June 14, 2024
There
is
no
diagnostic
biomarker
that
can
reliably
detect
Guillain-Barré
syndrome
(GBS)
or
chronic
inflammatory
demyelinating
polyneuropathy
(CIDP).
Diagnosis
relies
upon
integrating
key
clinical
characteristics
and
relevant
supportive
data.
Consequently,
misdiagnosis
delayed
diagnosis
are
common.
Diagnostic
criteria
have
proven
valuable
resources
to
improve
diagnosis,
but
underutilized
during
routine
care.
Language: Английский
Observing temporary changes in gait using a mobile phone
E3S Web of Conferences,
Journal Year:
2024,
Volume and Issue:
541, P. 03007 - 03007
Published: Jan. 1, 2024
The
purpose
of
the
article
is
to
analyze
temporary
changes
in
human
gait,
parameters
which
are
recorded
using
accelerometer
a
mobile
phone
everyday
use.
work
presents
trends
field
personalized
medicine
and
monitoring
health
employees
manufacturing
sector
based
on
wearable
devices.
features
collecting
processing
data
person’s
gait
presented,
act
as
comprehensive
assessment
parameters.
results
year-long
research
presented.
Daily,
weekly
annual
identified.
analyzed
time
series
representing
double
steps
during
gait.
When
constructing
trends,
maximum
value
cross-correlation
function
segments
was
used.
Data
segmentation
carried
out
according
length
step.
Based
research,
an
assumption
made
about
possibility
recording
individual
characteristics
functioning
musculoskeletal
system
conducting
further
order
accumulate
statistical
material
identify
relationship
between
lifestyle
Language: Английский