Advanced Materials,
Journal Year:
2023,
Volume and Issue:
35(20)
Published: Feb. 27, 2023
Luminescent
monitoring
of
endogenous
hydrogen
peroxide
(H2
O2
)
in
tumors
is
conducive
to
understanding
metastasis
and
developing
novel
therapeutics.
The
clinical
transformation
obstructed
by
the
limited
light
penetration
depth,
toxicity
nano-probes,
lack
long-term
modes
up
days
or
months.
New
are
introduced
via
specific
probes
implantable
devices,
which
can
achieve
real-time
with
a
readout
frequency
0.01
s
for
months
years.
Near-infrared
dye-sensitized
upconversion
nanoparticles
(UCNPs)
fabricated
as
luminescent
probes,
specificity
reactive
oxygen
species
subtly
regulated
self-assembled
monolayers
on
surfaces
UCNPs.
Combined
passive
implanted
system,
20-day
H2
rat
model
ovarian
cancer
peritoneal
achieved,
depth
nano-probes
circumvented.
developed
show
great
potential
accelerating
biochemical
detection
methods.
Signal Transduction and Targeted Therapy,
Journal Year:
2024,
Volume and Issue:
9(1)
Published: Feb. 21, 2024
Abstract
Inflammation-associated
diseases
encompass
a
range
of
infectious
and
non-infectious
inflammatory
diseases,
which
continuously
pose
one
the
most
serious
threats
to
human
health,
attributed
factors
such
as
emergence
new
pathogens,
increasing
drug
resistance,
changes
in
living
environments
lifestyles,
aging
population.
Despite
rapid
advancements
mechanistic
research
development
for
these
current
treatments
often
have
limited
efficacy
notable
side
effects,
necessitating
more
effective
targeted
anti-inflammatory
therapies.
In
recent
years,
nanotechnology
has
provided
crucial
technological
support
prevention,
treatment,
detection
inflammation-associated
diseases.
Various
types
nanoparticles
(NPs)
play
significant
roles,
serving
vaccine
vehicles
enhance
immunogenicity
carriers
improve
targeting
bioavailability.
NPs
can
also
directly
combat
pathogens
inflammation.
addition,
facilitated
biosensors
pathogen
imaging
techniques
This
review
categorizes
characterizes
different
NPs,
summarizes
their
applications
It
discusses
challenges
associated
with
clinical
translation
this
field
explores
latest
developments
prospects.
conclusion,
opens
up
possibilities
comprehensive
management
Journal of Functional Biomaterials,
Journal Year:
2022,
Volume and Issue:
13(1), P. 27 - 27
Published: March 9, 2022
Two-dimensional
(2D)
nanomaterials
(e.g.,
graphene)
have
shown
to
a
high
potential
in
future
biomedical
applications
due
their
unique
physicochemical
properties
such
as
unusual
electrical
conductivity,
biocompatibility,
large
surface
area,
and
extraordinary
thermal
mechanical
properties.
Although
the
of
graphene
most
common
2D
has
been
extensively
investigated,
practical
use
other
nanoengineered
materials
beyond
transition
metal
dichalcogenides
(TMDs),
topological
insulators
(TIs),
phosphorene,
antimonene,
bismuthene,
metal–organic
frameworks
(MOFs)
MXenes
for
not
appreciated
so
far.
This
review
highlights
only
opportunities
various
research
areas
bioelectronics,
imaging,
drug
delivery,
tissue
engineering,
regenerative
medicine
but
also
addresses
risk
factors
challenges
ahead
from
medical
perspective
clinical
translation
materials.
In
conclusion,
perspectives
roadmap
are
outlined
applications.
Advanced Materials,
Journal Year:
2023,
Volume and Issue:
36(17)
Published: Sept. 29, 2023
Abstract
The
emergence
of
nano
innovations
in
membrane
distillation
(MD)
has
garnered
increasing
scientific
interest.
This
enables
the
exploration
state‐of‐the‐art
nano‐enabled
MD
membranes
with
desirable
properties,
which
significantly
improve
efficiency
and
reliability
process
open
up
opportunities
for
achieving
a
sustainable
water‐energy‐environment
(WEE)
nexus.
comprehensive
review
provides
broad
coverage
in‐depth
analysis
recent
membranes,
focusing
on
their
role
such
as
strong
liquid‐repellence,
high
resistance
to
scaling,
fouling,
wetting,
well
efficient
self‐heating
self‐cleaning
functionalities.
developments
nano‐enhanced
photothermal‐catalytic
applications
water‐energy
co‐generation
within
single
system
are
also
discussed.
Furthermore,
bottlenecks
identified
that
impede
scale‐up
nanoenhanced
future
roadmap
is
proposed
commercialiation.
holistic
overview
expected
inspire
research
development
efforts
fully
harness
potential
achieve
integration
water,
energy,
environment.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Nov. 15, 2024
Abstract
Nanotechnology
holds
immense
promise
in
revolutionising
healthcare,
offering
unprecedented
opportunities
diagnostics,
drug
delivery,
cancer
therapy,
and
combating
infectious
diseases.
This
review
explores
the
multifaceted
landscape
of
nanotechnology
healthcare
while
addressing
critical
aspects
safety
environmental
risks
associated
with
its
widespread
application.
Beginning
an
introduction
to
integration
we
first
delved
into
categorisation
various
materials
employed,
setting
stage
for
a
comprehensive
understanding
potential.
We
then
proceeded
elucidate
diverse
applications
nanotechnology,
spanning
medical
tissue
engineering,
targeted
gene
development
antimicrobial
agents.
The
discussion
extended
current
situation
surrounding
clinical
translation
commercialisation
these
cutting-edge
technologies,
focusing
on
nanotechnology-based
products
that
have
been
approved
globally
date.
also
discussed
considerations
nanomaterials,
both
terms
human
health
impact.
presented
vivo
nanomaterial
exposure,
relation
transport
mechanisms,
oxidative
stress,
physical
interactions.
Moreover,
highlighted
risks,
acknowledging
potential
implications
ecosystems
biodiversity.
Lastly,
strived
offer
insights
regulatory
governing
across
different
regions
globally.
By
synthesising
perspectives,
underscore
imperative
balancing
innovation
stewardship,
charting
path
forward
responsible
healthcare.
Graphical
abstract
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(11), P. 5842 - 5842
Published: May 27, 2024
This
study
provides
a
brief
discussion
of
the
major
nanopharmaceuticals
formulations
as
well
impact
nanotechnology
on
future
pharmaceuticals.
Effective
and
eco-friendly
strategies
biofabrication
are
also
highlighted.
Modern
approaches
to
designing
pharmaceutical
nanoformulations
(e.g.,
3D
printing,
Phyto-Nanotechnology,
Biomimetics/Bioinspiration,
etc.)
outlined.
paper
discusses
need
use
natural
resources
for
“green”
design
new
with
therapeutic
efficiency.
Nanopharmaceuticals
research
is
still
in
its
early
stages,
preparation
nanomaterials
must
be
carefully
considered.
Therefore,
safety
long-term
effects
not
overlooked.
The
testing
represents
an
essential
point
their
further
applications.
Vegetal
scaffolds
obtained
by
decellularizing
plant
leaves
represent
valuable,
bioinspired
model
nanopharmaceutical
that
avoids
using
animals.
Nanoformulations
critical
various
fields,
especially
pharmacy,
medicine,
agriculture,
material
science,
due
unique
properties
advantages
over
conventional
allows
improved
solubility,
bioavailability,
targeted
drug
delivery,
controlled
release,
reduced
toxicity.
have
transitioned
from
experimental
stages
being
vital
component
clinical
practice,
significantly
improving
outcomes
medical
fields
cancer
treatment,
infectious
diseases,
neurological
disorders,
personalized
advanced
diagnostics.
Here
key
points
highlighting
importance.
significant
challenges,
opportunities,
directions
mentioned
final
section.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Aug. 29, 2024
Thermoelectric
technology
has
recently
emerged
as
a
distinct
therapeutic
modality.
However,
its
effectiveness
is
significantly
limited
by
the
restricted
temperature
gradient
within
living
organisms.
In
this
study,
we
introduce
high-performance
plasmonic-thermoelectric
catalytic
therapy
utilizing
urchin-like
Cu
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(4), P. 1706 - 1734
Published: April 2, 2024
The
development
of
advanced
technologies
for
the
fabrication
functional
nanomaterials,
nanostructures,
and
devices
has
facilitated
biosensors
analyses.
Two-dimensional
(2D)
with
unique
hierarchical
structures,
a
high
surface
area,
ability
to
be
functionalized
target
detection
at
surface,
exhibit
potential
biosensing
applications.
electronic
properties,
mechanical
flexibility,
optical,
electrochemical,
physical
properties
2D
nanomaterials
can
easily
modulated,
enabling
construction
platforms
various
analytes
targeted
recognition,
sensitivity,
selectivity.
This
review
provides
an
overview
recent
advances
in
nanostructures
used
biosensor
wearable-sensor
healthcare
health-monitoring
Finally,
advantages
2D-nanomaterial-based
several
challenges
their
optimal
operation
have
been
discussed
facilitate
smart
high-performance
future.
Journal of Functional Foods,
Journal Year:
2024,
Volume and Issue:
116, P. 106192 - 106192
Published: May 1, 2024
People
worldwide
need
to
improve
their
health
or
intention
control
diseases
more
naturally
through
ingredients
incorporated
into
foods
and
beverages,
called
functional
foods.
Functional
include
probiotic
organisms
bioactive
compounds
dairy
fermentable
foods,
whose
consumption
is
recommended
for
various
vulnerable
groups
linked
the
stay
healthy.
The
increase
in
production
of
containing
live
probiotics
has
led
development
new
products,
particularly
non-dairy
type,
counteract
disadvantages
such
as
low
digestibility,
allergies,
intolerance,
increased
cholesterol,
saturated
fatty
acids,
consumer's
food
preference,
which
impacts
health.
In
this
sense,
continuous
matrices
application
nanotechnological
strategies
had
a
significant
impact
on
science,
providing
nano-encapsulation
systems
transport,
storage,
release
organisms,
preserving
properties
exert
beneficial
effects
without
affecting
sensory
characteristics
product.
This
paper
addresses
recent
advances
strains,
pointing
out
advantages
limitations
according
matrix
encapsulation
techniques
used.
Considerations
are
presented
design
based
nano-systems
that
allow
obtaining
quality
products
with
nutritional
value
high
bioavailability,
viability,
protect
from
factors
pH
temperature,
stability
compounds,
decrease
adverse
interactions
between
components
while
acting
controlled
systems.
Additionally,
toxicological
aspects
continue
toxicity
testing
intended
be
used
food,
even
when
dealing
raw
materials
recognized
non-toxic,
pointed
out,
considering
each
nanosystem
presents
different
properties.
As
research
use
progresses,
it
may
contribute
mitigating
environmental
damage.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(33)
Published: June 14, 2024
Infectious
diseases
caused
by
bacterial,
viral,
and
fungal
pathogens
present
significant
global
health
challenges.
The
rapid
emergence
of
antimicrobial
resistance
exacerbates
this
issue,
leading
to
a
scenario
where
effective
antibiotics
are
increasingly
scarce.
Traditional
antibiotic
development
strategies
proving
inadequate
against
the
swift
evolution
microbial
resistance.
Therefore,
there
is
an
urgent
need
develop
novel
with
mechanisms
distinct
from
those
existing
antibiotics.
Nanozybiotics,
which
nanozyme-based
antimicrobials,
mimic
catalytic
action
lysosomal
enzymes
in
innate
immune
cells
kill
infectious
pathogens.
This
review
reinforces
concept
nanozymes
provides
comprehensive
summary
recent
research
advancements
on
potential
candidates.
Initially,
nanozybiotics
categorized
based
their
activities,
mimicking
either
oxidoreductase-like
or
hydrolase-like
functions,
thereby
highlighting
superior
combating
then
discusses
progress
treating
infections,
confirming
as
translational
nanozybiotic-based
products,
including
hydrogels,
nanorobots,
sprays,
bandages,
masks,
protective
clothing,
also
considered.
Finally,
current
challenges
future
prospects
nanozybiotic-related
products
explored,
emphasizing
design
capabilities
for
applications.
