Food Microbiology, Journal Year: 2024, Volume and Issue: 127, P. 104681 - 104681
Published: Nov. 17, 2024
Language: Английский
Food Microbiology, Journal Year: 2024, Volume and Issue: 127, P. 104681 - 104681
Published: Nov. 17, 2024
Language: Английский
Trends in Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown, P. 104922 - 104922
Published: Feb. 1, 2025
Language: Английский
Citations
1Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)
Published: Feb. 23, 2025
Language: Английский
Citations
0CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION), Journal Year: 2025, Volume and Issue: unknown, P. 100550 - 100550
Published: April 1, 2025
Language: Английский
Citations
0Genome, Journal Year: 2025, Volume and Issue: 68, P. 1 - 23
Published: Jan. 1, 2025
Canada has made significant contributions to the field of plant biochemistry, with numerous researchers actively focusing on elucidating biosynthetic pathways specialized metabolites and producing these compounds in heterologous systems, such as bacteria, yeast, or other species. The review aims highlight strengths Canadian research this domain over last three decades. It will describe advances pathway elucidation, enzyme characterization, production enzymes particularly areas alkaloids, terpenoids, phenolic compounds. have not only pivotal scientific discoveries but also ensured continuity excellence by mentoring new generations principal investigators metabolites. These warrant recognition financial support retain future talent maintain Canada's leadership progress global stage.
Language: Английский
Citations
0Journal of Asian Natural Products Research, Journal Year: 2023, Volume and Issue: 26(5), P. 652 - 662
Published: Oct. 27, 2023
Alkaloids are among the most important and best-known secondary metabolites as sources of new drugs from medicinal plants marine organisms. A phytochemical investigation whole plant Crinum asiaticum var. sinicum resulted in isolation seven alkaloids (1–7), including one dimeric compound, bis-(-)-8-demethylmaritidine (1). Their structures were elucidated using NMR HR-ESI-MS. The absolute configuration compound 1 was established by circular dichroism spectroscopy. All isolated compounds evaluated for their inhibitory effects on acetylcholinesterase (AChE) activity vitro. Among them, exhibited potent AChE inhibition. Moreover, molecular docking dynamics simulations carried out active to investigate binding interactions behavior protein-ligand complex. Therefore, may be a potential candidate effectively treating Alzheimer's disease.
Language: Английский
Citations
4Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15
Published: June 19, 2024
Graphical Abstract Therapeutic mechanisms of natural alkaloids in epilepsy treatment.
Language: Английский
Citations
1Journal of Pharmacological and Toxicological Methods, Journal Year: 2024, Volume and Issue: unknown, P. 107569 - 107569
Published: Oct. 1, 2024
Language: Английский
Citations
0PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e17965 - e17965
Published: Sept. 9, 2024
Citrus aurantium L., sometimes known as “sour orange,” is an important Chinese herb with young, immature fruits, or “zhishi,” that are high in synephrine. Synephrine a commonly utilized natural chemical promising applications effectively increasing metabolism, heat expenditure, energy level, oxidative fat, and weight loss. However, little about the genes pathways involved synephrine production during critical developmental stages of C. which limits development industry. According to this study, concentration gradually decreased fruit developed. Transcriptome sequencing was used examine DEGs associated connections served foundation for creating synephrine-rich L. Comparisons conducted between different obtain DEGs, number varied from 690 3,019. Tyrosine tryptophan biosynthesis, glycolysis/gluconeogenesis, pentose phosphate pathway, phenylalanine, tyrosine metabolism were main KEGG substantially enriched. The results showed 25 among these may be related synthesis. WGCNA one-way ANOVA analysis adoption variance across groups suggested 11 might play crucial role synthesis should therefore further analyzed. We also selected six at random analyzed their expression levels by RT-qPCR, repeatability reliability demonstrated our finished RNA-seq study results. These useful selecting modifying increase quantity sour oranges.
Language: Английский
Citations
0Food Microbiology, Journal Year: 2024, Volume and Issue: 127, P. 104681 - 104681
Published: Nov. 17, 2024
Language: Английский
Citations
0