Editora Creative eBooks, Journal Year: 2021, Volume and Issue: unknown, P. 134 - 143
Published: Jan. 1, 2021
Editora Creative eBooks, Journal Year: 2021, Volume and Issue: unknown, P. 134 - 143
Published: Jan. 1, 2021
Sağlık Bilimlerinde Değer, Journal Year: 2023, Volume and Issue: unknown
Published: Dec. 4, 2023
Aim: Clinical trials continue for several medical protocols COVID-19. Colchicine is an anti-inflammatory agent that highly used medicament autoimmune disorders, including Familial Mediterranean Fever (FMF). Based on immunity disrupting the pathogenesis of SARS-CoV-2, we aimed to describe clinical course SARS-CoV-2 infection in patients with childhood-onset FMF colchicine treatment. Material and Methods: We prepared a survey investigating contact histories, presentation treated questioned their parents via phone calls or during outpatient visits. In addition, record history, treatment, medication history were obtained from hospital database. Results: A total 171 patients, 99 (57.9%) male 72 (42.1%) female, diagnosed who have been under treatment at least one month included study. Among 56 (32.7%) confirmed COVID-19 case; 43 (25.1%) suspected family member 13 (7.6%) non-family contact. Only 15 (8.8%) PCR disease; all had mild symptoms, none required antiviral hospitalized. The dose duration use did not significantly differ between COVID (p=0.112, p=0.344, respectively). Conclusion: concluded pediatric receiving may be increased risk being infected severe symptoms
Language: Английский
Citations
0Authorea (Authorea), Journal Year: 2022, Volume and Issue: unknown
Published: July 25, 2022
Background and Aims: Worldwide, the incidence of COVID-19 is lower in children than adults symptoms are less severe. So far, few studies from Latin America have been published on behavior with cancer. Purpose : To characterize epidemiology, clinical course, morbidity, mortality cancer COVID-19. Methods: All patients registered Argentine National Pediatric Cancer Registry (ROHA) diagnosis SARS-CoV-2 between December 4, 2020, May 3, 2022 were included. Variables analyzed were: sex, age at diagnosis, presentation symptom severity, tumor type, intensive care requirement, specific treatment for COVID-19, vital status, cause death. Mortality was comparing three main waves. Results: Overall, 888 infection (484 females); 437 (49.2%) had leukemia, followed by central nervous system tumors (CNS-T) 120 (13.5%). Of children, 57.2% (n=508) symptomatic; 75% febrile, 37% (n=210) neutropenia; 17.1% (n=152) diagnosed within one month diagnosis. A total 154 severe or critical (17%). In this study, 112 deaths reported, 105 (94%) due to disease progression, sepsis, comorbidities, complications. Seven (0.8%) died all leukemia/lymphoma. No association found waves analyzed. Conclusions: Based ROHA data, we may conclude that pediatric patients, contrary what initially expected, morbidity not increased.
Language: Английский
Citations
0Editora Creative eBooks, Journal Year: 2021, Volume and Issue: unknown, P. 104 - 112
Published: Jan. 1, 2021
Citations
0Editora Creative eBooks, Journal Year: 2021, Volume and Issue: unknown, P. 352 - 360
Published: Jan. 1, 2021
Citations
0Editora Creative eBooks, Journal Year: 2021, Volume and Issue: unknown, P. 134 - 143
Published: Jan. 1, 2021
Citations
0