Quantitative Analysis of Retinal and Choroidal Microvascular Changes after Endonasal Endoscopic Pituitary Adenoma Resection: An Octa Study
Chen Liu,
No information about this author
Linhao Wang,
No information about this author
Yonggang Wu
No information about this author
et al.
Published: Jan. 1, 2025
Language: Английский
The Influence of Malnutrition-Sarcopenia Syndrome on Chorioretinal Microvasculature Using Optical Coherence Tomography Angiography
Photodiagnosis and Photodynamic Therapy,
Journal Year:
2025,
Volume and Issue:
unknown, P. 104549 - 104549
Published: March 1, 2025
To
probe
into
the
effects
of
malnutrition-sarcopenia
syndrome
on
changes
retinal
and
choroidal
microvasculature.
achieve
our
goals,
we
employed
optical
coherence
tomography
angiography
(OCTA),
a
cutting-edge
non-invasive
imaging
technique,
to
compare
parameters
in
controlled
setting.
A
total
22
participants
diagnosed
with
Malnutrition-Sarcopenia
Syndrome
were
enrolled
alongside
healthy
subjects
matched
for
age
gender
as
controls.
Parameters
under
scrutiny
included
inner
vessel
flow
density
(VFD),
thickness,
vascularity
index
(CVI).
Linear
regression
analyses
performed
identify
any
significant
variations
systemic
profles
associated
parameters.
Our
data
unveiled
substantial
discrepancies
retinochoroidal
microvascular
health
between
patient
cohort
control
group.
Specifically,
patients
showcased
notably
diminished
values
VFD,
thickness
CVI,
all
extreme
statistical
significance
(p<0.0001).
Further,
body
mass
(BMI)
exhibited
noteworthy
positive
association
(p=0.026),
whereas
skeletal
muscle
(SMI)
showed
similar
trend
CVI
through
both
univariate
multiple
linear
analyses.
Besides,
pearson's
correlation
analysis
also
indicated
that
SMI
was
positively
correlated
sarcopenia
patients.
The
collective
evidence
suggests
malnutrition
coupled
exerts
deleterious
chorioretinal
microvasculature,
potential
repercussions
visual
function.
This
research
underscores
imperative
proactive
monitoring
early
intervention
targeting
microvasculature
battling
syndrome.
Language: Английский
Assessment of retinochoroidal microvasculature in young Chinese Han and Uyghur adults with mild-moderate myopia: An OCTA study
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 8, 2025
Abstract
Objective
To
compare
the
differences
in
retinochoroidal
microvasculature
between
Han
and
Uyghur
population
with
mild-moderate
myopia
using
optical
coherence
tomography
angiography
(OCTA)
.
Method
This
prospective
cross-sectional
study
included
60
young
Chinese
subjects.They
are
divided
into
two
groups
according
to
their
ethnics
(Han
group
group).
All
subjects
underwent
ophthalmic
screening
examinations.
Retinal
choroidal
parameters
were
evaluated
swept-source
OCTA
(SS-OCTA),
including
retinal
thickness,
vessel
flow
density
(VFD),
foveal
avascular
zone
(FAZ)
area,
vascularity
volume
index
(CVV
CVI)
vascular
length
(VLD).
Results
had
mean
ages
of
24.93
±
1.70
25.57
1.36,
respectively
(
p
=
0.116).
No
significant
found
parameters,
VFD
FAZ
area
groups.
Compared
population,
Uyghurs
have
thicker
thickness
(
P
=
0.004),
higher
CVV
0.002)
CVI
0.003).
Axial
(AL)
was
negatively
associated
VFD-SCP,
VFD-DCP,
VFD-whole
retina
VFD-choriocapillaris
layer
based
on
univariate
linear
regression
analysis.
However,
only
AL
after
correction
for
age
gender
multifactor
For
subjects,
no
be
age,
both
Conclusion
Young
significantly
compared
matched
which
may
partially
elucidate
etiological
mechanisms
underlying
reduced
prevalence
observed
within
cohort.
Language: Английский
Quantitative Analysis of Retinal and Choroidal Microvascular Changes After Endonasal Endoscopic Pituitary Adenoma Resection: An OCTA Study
Chen Liu,
No information about this author
Linhao Wang,
No information about this author
Yonggang Wu
No information about this author
et al.
Photodiagnosis and Photodynamic Therapy,
Journal Year:
2025,
Volume and Issue:
unknown, P. 104639 - 104639
Published: May 1, 2025
This
study
used
swept-source
optical
coherence
tomography
angiography
(SS-OCTA)
to
compare
retinal
and
choroidal
vascular
parameter
changes
before
after
transsphenoidal
surgery
in
pituitary
adenoma
(PA)
patients,
these
with
healthy
controls,
order
evaluate
its
predictive
value
for
visual
recovery
determine
the
optimal
timing
surgery.
23
PA
patients
(46
eyes)
25
volunteers
(50
were
included.
The
group
was
followed
up
at
1
week
month
postoperatively.
Retinal
parameters
macula(M)
area
optic
nerve
head(ONH)
assessed,
including
thickness(T),
volume(V),
flow
density
(VFD),
foveal
avascular
zone
(FAZ),
volume
(CVV)
index
(CVI).
Comparison
of
morphology
blood
between
case
control
showed
significant
increases
deep
capillary
plexus
(DCP)
thickness
macula.
superficial
(SCP)
thickness,
volume,
large
medium
vessels
(LMCV)
CVI
(p
=
0.032)
disc
area,
as
well
all
indicators
FAZ
significantly
reduced.
Compared
preoperative
values,
a
postoperatively,
SCP-T
SCP-V
DCP
perimeter
decreased,
while
SCP
VFD
within
300
μm
(FAZ300)
increased
0.047).
LMCV
matrix
(CSI),
0.022)
DCP-T
SCP-FAZ300
0.0282).
Tumor
size
most
important
factor
affecting
parameters.
SCP-T,
CSI,
CVI,
other
lower
compared
controls.
These
further
decreased
decompression
surgery,
likely
due
secondary
from
atrophy
caused
by
tumor
compression.
continulous
improvement
μm(FAZ300)
may
be
related
decompression,
macular
cells
remain
intact.
parameters-SCP-FAZ300,
LMCV-CVI/CSI,
SCP-ONH
T/V-collectively
quantify
postoperative
acuity(VA)and
field(VF)
outcomes
guide
surgical
selection.These
findings
suggest
that
require
earlier
screening
treatment,
OCTA
can
serve
an
non-invasive
evaluation
tool.
Language: Английский