Quantitative Analysis of Retinal and Choroidal Microvascular Changes After Endonasal Endoscopic Pituitary Adenoma Resection: An OCTA Study DOI Creative Commons
Chen Liu, Linhao Wang,

Yonggang Wu

et al.

Photodiagnosis and Photodynamic Therapy, Journal Year: 2025, Volume and Issue: unknown, P. 104639 - 104639

Published: May 1, 2025

This study used swept-source optical coherence tomography angiography (SS-OCTA) to compare retinal and choroidal vascular parameter changes before after transsphenoidal surgery in pituitary adenoma (PA) patients, these with healthy controls, order evaluate its predictive value for visual recovery determine the optimal timing surgery. 23 PA patients (46 eyes) 25 volunteers (50 were included. The group was followed up at 1 week month postoperatively. Retinal parameters macula(M) area optic nerve head(ONH) assessed, including thickness(T), volume(V), flow density (VFD), foveal avascular zone (FAZ), volume (CVV) index (CVI). Comparison of morphology blood between case control showed significant increases deep capillary plexus (DCP) thickness macula. superficial (SCP) thickness, volume, large medium vessels (LMCV) CVI (p = 0.032) disc area, as well all indicators FAZ significantly reduced. Compared preoperative values, a postoperatively, SCP-T SCP-V DCP perimeter decreased, while SCP VFD within 300 μm (FAZ300) increased 0.047). LMCV matrix (CSI), 0.022) DCP-T SCP-FAZ300 0.0282). Tumor size most important factor affecting parameters. SCP-T, CSI, CVI, other lower compared controls. These further decreased decompression surgery, likely due secondary from atrophy caused by tumor compression. continulous improvement μm(FAZ300) may be related decompression, macular cells remain intact. parameters-SCP-FAZ300, LMCV-CVI/CSI, SCP-ONH T/V-collectively quantify postoperative acuity(VA)and field(VF) outcomes guide surgical selection.These findings suggest that require earlier screening treatment, OCTA can serve an non-invasive evaluation tool.

Language: Английский

Quantitative Analysis of Retinal and Choroidal Microvascular Changes after Endonasal Endoscopic Pituitary Adenoma Resection: An Octa Study DOI
Chen Liu, Linhao Wang,

Yonggang Wu

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
The Influence of Malnutrition-Sarcopenia Syndrome on Chorioretinal Microvasculature Using Optical Coherence Tomography Angiography DOI Creative Commons
Yiming Cheng, Jiawei Wang, Shanshan Li

et al.

Photodiagnosis and Photodynamic Therapy, Journal Year: 2025, Volume and Issue: unknown, P. 104549 - 104549

Published: March 1, 2025

To probe into the effects of malnutrition-sarcopenia syndrome on changes retinal and choroidal microvasculature. achieve our goals, we employed optical coherence tomography angiography (OCTA), a cutting-edge non-invasive imaging technique, to compare parameters in controlled setting. A total 22 participants diagnosed with Malnutrition-Sarcopenia Syndrome were enrolled alongside healthy subjects matched for age gender as controls. Parameters under scrutiny included inner vessel flow density (VFD), thickness, vascularity index (CVI). Linear regression analyses performed identify any significant variations systemic profles associated parameters. Our data unveiled substantial discrepancies retinochoroidal microvascular health between patient cohort control group. Specifically, patients showcased notably diminished values VFD, thickness CVI, all extreme statistical significance (p<0.0001). Further, body mass (BMI) exhibited noteworthy positive association (p=0.026), whereas skeletal muscle (SMI) showed similar trend CVI through both univariate multiple linear analyses. Besides, pearson's correlation analysis also indicated that SMI was positively correlated sarcopenia patients. The collective evidence suggests malnutrition coupled exerts deleterious chorioretinal microvasculature, potential repercussions visual function. This research underscores imperative proactive monitoring early intervention targeting microvasculature battling syndrome.

Language: Английский

Citations

0
Assessment of retinochoroidal microvasculature in young Chinese Han and Uyghur adults with mild-moderate myopia: An OCTA study DOI
Jie Zhang, Lei Yang, Yihan Zhao

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

Abstract Objective To compare the differences in retinochoroidal microvasculature between Han and Uyghur population with mild-moderate myopia using optical coherence tomography angiography (OCTA) . Method This prospective cross-sectional study included 60 young Chinese subjects.They are divided into two groups according to their ethnics (Han group group). All subjects underwent ophthalmic screening examinations. Retinal choroidal parameters were evaluated swept-source OCTA (SS-OCTA), including retinal thickness, vessel flow density (VFD), foveal avascular zone (FAZ) area, vascularity volume index (CVV CVI) vascular length (VLD). Results had mean ages of 24.93 ± 1.70 25.57 1.36, respectively (p = 0.116). No significant found parameters, VFD FAZ area groups. Compared population, Uyghurs have thicker thickness (P = 0.004), higher CVV 0.002) CVI 0.003). Axial (AL) was negatively associated VFD-SCP, VFD-DCP, VFD-whole retina VFD-choriocapillaris layer based on univariate linear regression analysis. However, only AL after correction for age gender multifactor For subjects, no be age, both Conclusion Young significantly compared matched which may partially elucidate etiological mechanisms underlying reduced prevalence observed within cohort.

Language: Английский

Citations

0
Quantitative Analysis of Retinal and Choroidal Microvascular Changes After Endonasal Endoscopic Pituitary Adenoma Resection: An OCTA Study DOI Creative Commons
Chen Liu, Linhao Wang,

Yonggang Wu

et al.

Photodiagnosis and Photodynamic Therapy, Journal Year: 2025, Volume and Issue: unknown, P. 104639 - 104639

Published: May 1, 2025

This study used swept-source optical coherence tomography angiography (SS-OCTA) to compare retinal and choroidal vascular parameter changes before after transsphenoidal surgery in pituitary adenoma (PA) patients, these with healthy controls, order evaluate its predictive value for visual recovery determine the optimal timing surgery. 23 PA patients (46 eyes) 25 volunteers (50 were included. The group was followed up at 1 week month postoperatively. Retinal parameters macula(M) area optic nerve head(ONH) assessed, including thickness(T), volume(V), flow density (VFD), foveal avascular zone (FAZ), volume (CVV) index (CVI). Comparison of morphology blood between case control showed significant increases deep capillary plexus (DCP) thickness macula. superficial (SCP) thickness, volume, large medium vessels (LMCV) CVI (p = 0.032) disc area, as well all indicators FAZ significantly reduced. Compared preoperative values, a postoperatively, SCP-T SCP-V DCP perimeter decreased, while SCP VFD within 300 μm (FAZ300) increased 0.047). LMCV matrix (CSI), 0.022) DCP-T SCP-FAZ300 0.0282). Tumor size most important factor affecting parameters. SCP-T, CSI, CVI, other lower compared controls. These further decreased decompression surgery, likely due secondary from atrophy caused by tumor compression. continulous improvement μm(FAZ300) may be related decompression, macular cells remain intact. parameters-SCP-FAZ300, LMCV-CVI/CSI, SCP-ONH T/V-collectively quantify postoperative acuity(VA)and field(VF) outcomes guide surgical selection.These findings suggest that require earlier screening treatment, OCTA can serve an non-invasive evaluation tool.

Language: Английский

Citations

0