Wirelessly Powered Visible Light-Emitting Implant for Surgical Guidance during Lumpectomy DOI Creative Commons

Sunghoon Rho,

Roy A. Stillwell,

Kedi Yan

et al.

Sensors, Journal Year: 2024, Volume and Issue: 24(17), P. 5639 - 5639

Published: Aug. 30, 2024

Achieving negative surgical margins, defined as no tumor found on the edges of resected tissue, during lumpectomy for breast cancer is critical mitigating risk local recurrence. To identify nonpalpable tumors that cannot be felt, pre-operative placements wire and wire-free localization devices are typically employed. Wire-free approaches have significant practical advantages over wired techniques. In this study, we introduce an innovative system comprising a light-emitting diode (LED)-based implantable device handheld system. The device, which needle injectable free, utilizes multiple wirelessly powered LEDs to provide direct visual guidance lumpectomy. Two distinct colors, red blue, clear indication tissue depth: blue light absorbed strongly in visible within close range <1 cm, while remains through several centimeters tissue. LEDs, integrated with impedance-matching circuit receiver coil, encapsulated biocompatible epoxy injection 12 G needle. Our findings demonstrate implant exhibits clearly perceivable depth-dependent color changes >2 cm ex vivo chicken bovine muscle using less than 4 W transmitted power from antenna. These miniaturized needle-injectable show promise improving tumors.

Language: Английский

Wirelessly Powered Visible Light-Emitting Implant for Surgical Guidance during Lumpectomy DOI Creative Commons

Sunghoon Rho,

Roy A. Stillwell,

Kedi Yan

et al.

Sensors, Journal Year: 2024, Volume and Issue: 24(17), P. 5639 - 5639

Published: Aug. 30, 2024

Achieving negative surgical margins, defined as no tumor found on the edges of resected tissue, during lumpectomy for breast cancer is critical mitigating risk local recurrence. To identify nonpalpable tumors that cannot be felt, pre-operative placements wire and wire-free localization devices are typically employed. Wire-free approaches have significant practical advantages over wired techniques. In this study, we introduce an innovative system comprising a light-emitting diode (LED)-based implantable device handheld system. The device, which needle injectable free, utilizes multiple wirelessly powered LEDs to provide direct visual guidance lumpectomy. Two distinct colors, red blue, clear indication tissue depth: blue light absorbed strongly in visible within close range <1 cm, while remains through several centimeters tissue. LEDs, integrated with impedance-matching circuit receiver coil, encapsulated biocompatible epoxy injection 12 G needle. Our findings demonstrate implant exhibits clearly perceivable depth-dependent color changes >2 cm ex vivo chicken bovine muscle using less than 4 W transmitted power from antenna. These miniaturized needle-injectable show promise improving tumors.

Language: Английский

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