Chemosphere, Journal Year: 2025, Volume and Issue: 377, P. 144335 - 144335
Published: April 9, 2025
Language: Английский
Chemosphere, Journal Year: 2025, Volume and Issue: 377, P. 144335 - 144335
Published: April 9, 2025
Language: Английский
Journal of Toxicology and Environmental Health Part B, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 24
Published: March 25, 2025
Sulfoxaflor (SFX) is a newly registered IRAC Group 4C nAChR-receptor-agonist systemic insecticide that used to control sap-sucking insects in variety of crops. SFX has short half-life (< 2 days) agricultural soil and only as foliar-applied product. Pollinators such honey bees could be exposed directly spray if application occurs shortly before or during blooming flowers, or, systemic, via oral exposures nectar pollen collected by bees. Guided Weight-of-Evidence rubric, this paper critically assessed studies on the fate bee-relevant matrices submitted registrant several jurisdictions well few published open scientific literature. These provided data for residues and/or from 16 crops grown countries both hemispheres. transformation products were detected pollen. Transformation have low hazard honeybees, so focus was parent material, SFX, which observed dissipate rapidly after application. Dietary No-Observed-Adverse-Effect-Concentrations (NOAEC) derived results 10-day continuous feeding adult (0.50 mg kg-1 diet d-1) larval honeybees (1.69 precautionary toxicity benchmarks characterize hazards. In paper, we tiered process. The initial screening tier based greatest concentration measured matrix. For scenarios did not pass Tier-1, second time-weighted average (area under curve, AUC) matrix more realistic measure exposure. Of 90 use characterized, 36 benchmark ≥1concentration exceeding NOAEC. When AUC exposure estimated these scenarios, 3 benchmark. three anthers alfalfa California, strawberries France, peaches Michigan. two-tier procedure assessment lessened need further 97% reduced characterizing hazards field-level whole-hive tests conducted controlled conditions
Language: Английский
Citations
6Chemosphere, Journal Year: 2025, Volume and Issue: 377, P. 144335 - 144335
Published: April 9, 2025
Language: Английский
Citations
0