Foods,
Journal Year:
2024,
Volume and Issue:
13(8), P. 1229 - 1229
Published: April 17, 2024
Pleurotus
eryngii
(PE)
has
been
sought
after
for
its
various
health
benefits
and
high
content
of
phenolic
compounds.
This
study
explored
the
feasibility
steam
explosion
(SE)-assisted
extraction
polysaccharides
with
antioxidant
capacities
from
PE.
An
orthogonal
experimental
design
(OED)
was
used
to
optimize
SE-assisted
The
influence
optimized
on
physicochemical
properties
PE
determined
by
scanning
electron
microscopy
(SEM),
Fourier
transform
infrared
spectroscopy
(FTIR),
monosaccharide
compositional
analysis
capacity
assays.
Under
optimal
SE
conditions,
increased
polysaccharide
yield
138%
compared
without
SE-assistance.
In
addition,
SEM
demonstrated
that
markedly
altered
spatial
structure
(PEP),
revealed
this
pretreatment
significantly
proportions
some
monosaccharides,
such
as
glucose,
rhamnose
arabinose,
in
isolated
PEP.
FTIR
spectra
indicated
no
change
major
chemical
functional
groups
PEP
extracted
had
free
radical
scavenging
capacities.
conclusion,
appears
be
a
novel
technology,
which
increases
yields
efficiency
can
increase
biological
activity
extracts.
Foods,
Journal Year:
2023,
Volume and Issue:
12(11), P. 2133 - 2133
Published: May 25, 2023
From
Siraitia
grosvenorii,
a
natural
polysaccharide
named
SGP-1
was
discovered,
and
its
purity
determined
to
be
96.83%.
Its
structure
is
glucan
with
4-,
6-
4,6-linked
glucose
units.
In
this
paper,
the
sulfated
derivative
S-SGP
of
prepared
by
chlorosulfonic
acid
method.
The
derivatives
were
analyzed
Fourier
transform
infrared
spectroscopy
(FT-IR),
gel
permeation
chromatography
(GPC),
scanning
electron
microscopy
(SEM).
degree
substitution
(DS)
0.62,
weight
average
molecular
(Mw)
1.34
×
104
Da.
While
retaining
morphological
characteristics
polysaccharides,
appeared
large
number
spherical
structures
strong
intermolecular
forces.
in
vitro
activity
study
showed
that
had
ability
scavenge
DPPH
radicals,
hydroxyl
radicals
superoxide
anions,
scavenging
power
tended
increase
concentration.
It
can
inhibit
growth
human
hepatoma
cells
(HepG2),
breast
cancer
(MDA-MB-231)
non-small
cell
lung
(A549)
vitro.
addition,
treatment
A549
sulfuric
decrease
mitochondrial
membrane
potential,
induce
apoptosis,
alter
expression
apoptosis-related
mRNA
protein.
Journal of Integrative Neuroscience,
Journal Year:
2023,
Volume and Issue:
22(4)
Published: July 17, 2023
Background:
Stress
can
lead
to
emotional
and
mental
symptoms
such
as
anxiety,
sadness,
panic
attacks,
depression.
Malic
acid
was
chosen
due
malic
has
the
ability
improve
antioxidant
activity
improves
liver
damage.
This
study
evaluates
anti-depressant
in
hypothalamus
of
stressed
rats.
Methods:
Thirty-six
male
albino
rats
were
divided
into
2
equal
groups;
Normal
chronic
mild
stress
(CMS)
3
control,
acid,
venlafaxine
drug
groups:
normal
administered
orally
with
1
mL
saline
solution,
250
mg/kg
20
drug,
respectively.
CMS
CMS,
+
drug:
All
above-mentioned
treatments
once
a
day
by
oral
gavage
for
6
weeks.
Results:
The
obtained
results
revealed
that
animal
behavioral
tests
forced
swimming
test,
tail
suspension
sucrose
preference
open-field
test
(center
square
entries
center
duration
distance
travelled
test),
norepinephrine,
dopamine,
serotonin,
γ-aminobutyric
nicotinamide-adenine
dinucleotide
phosphate
(NADPH)
oxidase
activity,
oxidative
index,
conjugated
dienes,
catalase,
glutathione
peroxidase,
superoxide
dismutase,
malondialdehyde,
interleukin-6,
tumor
necrosis
factor-α,
interleukin-10,
interleukin-1β,
sodium/potassium-ATPase
histamine-N-methyl
transferase
(Hnmt)
tyrosine
hydroxylase
(TH)
enzymes
rats,
returned
approaching
state
group
after
treating
Conclusions:
ameliorated
stressed-related
it
inhibited
anion
neuro-inflammation
Phytochemical Analysis,
Journal Year:
2024,
Volume and Issue:
35(4), P. 873 - 888
Published: Feb. 17, 2024
Abstract
Introduction
Zhou
Tian
Formula
(ZTF)
is
an
antidepressant
traditional
Chinese
medicine
utilized
widely
in
clinical
settings
for
the
treatment
of
patients
with
depression.
However,
shortcomings
persist
its
extraction
technology
and
quality
control.
Objective
This
study
aimed
to
propose
a
methodology
ZTF
based
on
analytic
hierarchy
process
(AHP)–criteria
importance
through
intercriteria
correlation
(CRITIC)
method
establish
control
framework
efficient
transfer
index
components.
Method
Firstly,
we
analyzed
chemical
components
determined
optimal
technology.
Secondly,
calculated
efficiency
during
conversion
water
decoction
extract
powder
subsequently
granules.
Thirdly,
established
HPLC
fingerprints
15
batches
decoction,
powder,
We
employed
SIMCA
software
analyze
chemicals
responsible
variations
among
different
Results
process.
The
average
ferulic
acid,
puerarin,
mirificin,
isoferulic
calycosin
granules
exceeded
41%.
exhibited
similarity
exceeding
0.890.
Variable
projection
values
indicated
that
calycosin,
puerarin
were
primary
contributors
variations.
Conclusions
AHP‐CRITIC
method,
coupled
orthogonal
array
design,
could
be
used
exploring
In
addition,
rules
governing
from
granules,
applied
evaluation
assessment
ZTF.
Natural Products and Bioprospecting,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: June 6, 2023
Four
polysaccharides
(MCPa,
MCPb,
MCPc,
MCPd)
were
obtained
from
Lepidium
meyenii
Walp.
Their
structures
characterized
by
chemical
and
instrumental
methods
including
total
sugar,
uronic
acid
protein
content
determination,
UV,
IR
NMR
spectroscopy,
as
well
monosaccharide
composition
determination
methylation
analyses.
a
group
of
glucans
with
different
molecular
weights
ranging
3.12
to
14.4
kDa,
shared
similar
backbone
chain
consisting
(1→4)-glucose
linkages
branches
attached
C-3
C-6.
Furthermore,
bioactivity
assay
showed
that
MCPs
had
concentration-dependent
inhibitory
activity
on
α-glucosidase.
MCPb
(Mw
=
10.1
kDa)
MCPc
5.62
moderate
exhibited
higher
compared
MCPa
MCPd.
