Frontiers in Plant Science,
Journal Year:
2024,
Volume and Issue:
15
Published: March 14, 2024
Introduction
Dendrobium
is
an
epiphytic
herb
plant
with
neuroprotective,
gastroprotective,
anti-inflammatory,
and
immunomodulatory
effects.
It
often
found
attached
to
tree
trunks
or
rocks.
With
the
development
of
dendrobium
industry,
numerous
patterns
exist,
such
as
crushed
stone,
stump,
sawdust.
The
study
metabolites
endophytes
D.
nobile
under
different
patterns,
which
revealed
effects
on
from
perspectives
metabolomics
microbiology,
great
significance
for
healthy
.
Methods
In
study,
five
grown
in
same
environment
were
selected.
investigated
by
widely
targeted
metabolomics,
sequenced
using
high-throughput
sequencing
methods.
Then,
a
correlation
analysis
between
was
performed.
Results
A
total
1,032
annotated
There
are
more
flavonoids
phenolic
acids
accumulated
pattern
Danxia
whereas
accumulation
lipids
other
16
differential
screened
out.
endophyte
composition
dominated
Proteobacteria
,
Actinomycetes
unidentified
bacteria,
Firmicutes
Cyanobacteria
For
endophytic
fungi,
Basidiomycota
Ascomycota
dominant
phyla
relative
abundance
Spirosoma
Nocardioides
Arrhenia
stone
significantly
higher
than
that
patterns.
According
analysis,
we
significant
Arrheni
Discussion
This
confirmed
quality
affected
its
possible
causes
microbiological
point
view.
Critical Reviews in Biotechnology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 19
Published: Jan. 6, 2025
This
comprehensive
review
aims
to
explore
and
consolidate
the
current
knowledge
on
dendrobine,
including
its
biological
activities,
molecular
mechanisms
of
action,
effects
various
physiological
processes,
potential
toxicity,
safety
considerations,
in
order
unlock
full
applications.
Dendrobine
has
diverse
effects,
anti-inflammatory,
antioxidant,
neuroprotective,
immunomodulatory,
anticancer
effects.
also
exerts
neuroprotective
by
boosting
neuronal
survival,
reducing
neuroinflammation,
regulating
neurotransmitter
release.
immunomodulatory
that
control
immune
cell
function
modify
immunological
responses.
exhibits
properties
decreasing
tumor
angiogenesis
metastasis,
causing
apoptosis
cancer
cells,
inhibiting
growth.
discusses
idea
a
circular
economy
produce
researching
cutting-edge
sustainable
methods
maximize
resource
efficiency
reduce
environmental
Additionally,
supporting
principles
for
production
outlining
future
study
areas,
this
discovery
will
help
use
dendrobine
variety
applications
while
preserving
environment.
Future
research
should
focus
advancing
application
personalized
medicine,
exploring
green
bioproduction
methods,
ensuring
ethical
sourcing
practices.
An
enhanced
understanding
synergistic
therapies
could
revolutionize
healthcare,
whereas
conservation
efforts
safeguard
ecological
impact.
Journal of Ethnopharmacology,
Journal Year:
2024,
Volume and Issue:
323, P. 117684 - 117684
Published: Jan. 1, 2024
Dendrobium
nobile
Lindl.
(DNL)
is
a
traditional
Chinese
ethnobotanical
herb.
Dendrobine
(DNE)
has
been
designated
as
quality
indicator
for
DNL
in
the
Pharmacopoeia.
DNE
exhibits
various
pharmacological
activities,
including
reduction
of
blood
lipids,
regulation
sugar
levels,
well
anti-inflammatory
and
antioxidant
properties.
Arabian Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
17(3), P. 105627 - 105627
Published: Jan. 20, 2024
This
work
was
aimed
to
investigate
the
α-glucosidase
inhibitory
potential
of
methanol,
petroleum
ether,
ethyl
acetate,
n-butanol,
and
water
extracts/fractions
four
Dendrobium
species,
which
are
traditional
medicinal
plants
over
centuries,
discovery
some
important
polyphenols
in
terms
lowering
blood
sugar
based
our
previous
research.
Furthermore,
enzyme
kinetics,
HPLC,
fluorescence
spectra,
molecular
docking
were
performed
provide
additional
insights
into
binding
mechanisms
between
individual
polyphenol
α-glucosidase.
All
organic
showed
promising
results
on
with
IC50
values
4.23–52.53
μg/mL.
The
EtOAcF
D.
chrysotoxum
(EtOAcF-DC)
possessed
lowest
value
(4.23
±
0.19
μg/mL)
against
And
an
obvious
correlation
existed
total
phenol
contents
inhition
capacity.
Schaftoside,
isoschaftoside,
2,4,7-trihydroxy-9,10-dihydrophenanthrene
(TD),
dihydroresveratrol,
coelonin,
nudol
(NU),
gigantol
(GT),
erianin,
tristin
identified
as
main
components
these
plants.
However,
only
TD,
NU,
GT
had
significant
activity
NU
discovered
simultaneously
EtOAc
fractions
(EtOAcFs)
species
occupied
higher
than
other
components,
thus
being
selected
objectives
for
deep
TD
from
first
reported
inhibitor
52.46
2.34
μg/mL,
almost
6.5
times
stronger
that
acarbose
(IC50
=
338.84
18.57
μg/mL),
signifying
it
a
candidate
treating
diabetes.
acted
uncompetitive
inhibitors
α-glucosidase,
while
EtOAcF-DC
exhibited
mixed-type
inhibition.
spectra
analysis
demonstrated
could
quenched
spectrum
significantly.
Interestingly,
by
unusual
static
quenching
method.
simulation
illustrated
three
interacted
primarily
through
hydrogen
bonds
van
der
Waals
interactions,
sites
supported
obtained
inhibition
kinetics.
study
revealed
phenolic-rich
compounds
be
inhibitors.
Frontiers in Plant Science,
Journal Year:
2025,
Volume and Issue:
15
Published: Jan. 20, 2025
Long-term
space
missions
will
require
high-quality
plants
that
are
edible,
medicinal,
and
ornamental,
to
support
the
physical
mental
health
of
astronauts
under
altered
gravity
conditions.
Anthocyanins
play
a
key
role
in
enhancing
medicinal
edible
value
ornamental
properties
plants.
However,
simulated
microgravity,
transcription
control
anthocyanin
biosynthesis
is
not
clear.
Here,
order
investigate
influences
microgravity
on
accumulation
further,
clones
Dendrobium
catenatum
were
exposed
for
20
days
The
content
leaves
increased
conditions
compared
with
gravity-treated
clones.
Furthermore,
based
transcriptome
sequencing,
differentially
expressed
genes
(DEGs),
weighted
gene
co-expression
network
analysis
combined
RT-qPCR,
we
identified
one
WRKY
gene,
DcaWRKY2
,
from
conditions,
which
indicated
may
be
involved
A
more
in-depth
evaluating
function
factor
was
silenced
by
virus-induced
silencing
resulted
increase
leaves,
expression
levels
pathway
(ABP)
structural
genes,
including
DcaCHS
DcaCHI
DcaF3H
DcaDFR
DcaANS
significantly.
This
research
provides
new
insights
into
how
can
affect
synthesis
illuminated
regulatory
effects
leaves’
pigmentation
microgravity.
Journal of Food Biochemistry,
Journal Year:
2025,
Volume and Issue:
2025(1)
Published: Jan. 1, 2025
Terpenoid
synthase
(TPS)
is
a
crucial
enzyme
catalyzing
terpenoid
synthesis
in
plants.
However,
the
TPS
gene
family
and
its
expression
patterns
different
growth
stages
of
Dendrobium
nobile
remain
unexplored.
This
study
aims
to
systematically
identify
analyze
members
using
whole
genome
sequencing.
Results
revealed
identification
50
members,
with
predicted
molecular
weights
ranging
from
14,531
162,002
Da.
Subfamilies
TPS‐a,
TPS‐b,
TPS‐c,
TPS‐e/f
were
detected
.
Furthermore,
UPLC‐Q/TOF‐MS
technology
was
utilized
sesquiterpenoid
compounds
stems
1‐year‐old
3‐year‐old
The
content
compounds,
including
dendroxine
dendronobiloside
A,
increased
plant
age.
That
increase
can
be
attributed
upregulation
sesquiterpene
synthase,
hypothesis
validated
through
transcriptome
sequencing,
qRT‐PCR,
docking.
results
over
time
suggest
that
may
play
role
regulating
conjunction
genes.
We
promote
development
into
food
field.
It
conducive
rational
utilization
