Molecules, Journal Year: 2025, Volume and Issue: 30(8), P. 1696 - 1696
Published: April 10, 2025
Medicinal plants from the genus Saururus are commonly used to treat inflammatory pathologies. They contain numerous bioactive compounds, notably polycyclic lignan sauchinone species chinensis. An in-depth analysis of benzoxanthenone lignans related sauchinone, and analogous products carpanone polemannones, has been carried out. The review reports product’s isolation, biosynthetic pathway, chemical strategies synthesize benzoxanthenones via liquid- solid-phase syntheses. metabolic pharmacokinetic properties discussed. At pharmacological level, is a potent blocker production pro-inflammatory mediators, such as nitric oxide prostaglandin E2, an efficient antioxidant agent. can be exploited combat multiple pathologies, liver injuries, renal dysfunction, osteoarthritis, bowel disease, ulcerative colitis, cancers. capacity natural product inhibit tumor cell proliferation reduce migration/invasion cancer cells development metastases underlined, together with regulation epithelial-mesenchymal transition immune checkpoints. Altogether, offers complete survey biochemical sauchinone-type benzoxanthenones.
Language: Английский