Crystal structure and Hirshfeld surface analysis of N-(4-nitrophenyl)-2-(piperidin-1-yl)acetamide (lidocaine analogue) DOI Creative Commons
Imane Maimoune, Benson M. Kariuki, Abderrazzak El Moutaouakil Ala Allah

et al.

Acta Crystallographica Section E Crystallographic Communications, Journal Year: 2024, Volume and Issue: 81(1), P. 69 - 73

Published: Dec. 23, 2024

In the title molecule, C 13 H 17 N 3 O , substituents on phenyl ring are rotated slightly out of mean plane but piperidine moiety is nearly perpendicular to that plane. crystal, C—H...O hydrogen bonds form chains molecules extending along c -axis direction, which linked by C=O...π(ring) interactions. A Hirshfeld surface analysis showed majority intermolecular interactions be H...H contacts while O...H/H...O second most numerous.

Language: Английский

Synthesis, Characterization, and Inhibition performance of 1,2,4-Triazolobenzodiazepine Derivatives as corrosion inhibitors: Insights from Experimental and Theoretical Studies DOI
Walid Ettahiri,

Marouane Ait Lahcen,

Driss Fadili

et al.

Materials Chemistry and Physics, Journal Year: 2025, Volume and Issue: unknown, P. 130419 - 130419

Published: Jan. 1, 2025

Language: Английский

Citations

3

Synthesis, characterization, theoretical, and experimental evaluation of novel imidazolone − based compounds as eco-friendly corrosion inhibitors for mild steel DOI
Walid Ettahiri, Abderrazzak El Moutaouakil Ala Allah,

Jamila Lazrak

et al.

Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: 140, P. 631 - 646

Published: Aug. 26, 2024

Language: Английский

Citations

12

Synthesis, characterization, theoretical, and evaluation of eco-friendly phenytoin-based corrosion inhibitors for mild steel DOI
Walid Ettahiri, Abderrazzak El Moutaouakil Ala Allah,

Jamila Lazrak

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: unknown, P. 135816 - 135816

Published: Nov. 1, 2024

Language: Английский

Citations

6

Synthesis, Characterization, Theoretical, and evaluation of Eco-Friendly benzimidazolylmethyl-pyrazole carboxylate Schiff Bases corrosion inhibitors for mild steel DOI
Walid Ettahiri, Mohamed Adardour, Driss Fadili

et al.

Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: 145, P. 337 - 359

Published: Oct. 18, 2024

Language: Английский

Citations

4

Phenyltriazolobenzodiazepine derivatives: Synthesis, characterisation, and electrochemical assessment as effective mild steel corrosion inhibitors in acidic environments DOI
Walid Ettahiri,

Samir Hmaimou,

Driss Fadili

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: 716, P. 136742 - 136742

Published: March 31, 2025

Language: Английский

Citations

0

The role of water and iodine in supramolecular assembly of a 2D coordination of benzimidazole derivate: X-ray crystallography and DFT calculations DOI Open Access
Sahaj A. Gandhi, Saurabh S. Soni, U. H. Patel

et al.

European Journal of Chemistry, Journal Year: 2025, Volume and Issue: 16(1), P. 7 - 19

Published: March 31, 2025

To understand the relationships between molecular structure and properties, as well to validate predictive models, density functional theory (DFT) experimental characterization of molecules are essential. In this study, we describe synthesis crystal 1,3-dimethyl-3H-benzimidazol-1-ium iodide monohydrate (DBZIW), which crystallizes in a monoclinic system with space group P21/c, = 8.9323(4) Å, b 7.1654(3) c 17.6425(8) β 101.432(2)°, V 1106.78(8) Å3, Z 4, T 293(2) K, μ(MoKα) 2.860 mm-1, Dcalc 1.753 g/cm3, 9452 reflections measured (4.652° ≤ 2Θ 55.512°), 2547 unique (Rint 0.0244, Rsigma 0.0222) were used all calculations. The asymmetric unit comprises [C9H11N2]+ molecule, an iodine ion (I-), water molecule. B3LYP/6-311++G(d,p) diffuse function was optimize structures (DBZ) (DBZW), while (DBZI) (DBZIW) optimized using B3LYP/Def2-TZVP method due presence ion. These optimizations performed Gaussian09 software, both models accurately predicted bond lengths, angles, torsion angles molecules. Furthermore, DFT calculations employed determine HOMO-LUMO energy levels, gap, softness, hardness, other quantum chemical parameters. A strong intermolecular hydrogen interaction, along aromatic ring fusion benzene imidazole, constitutes small but highly significant that has been confirmed. O1 atom molecule (I-) participate interaction (O-H···I) within packing DBZIW. network C-H···O contacts plays crucial role stability structure. Hirshfeld surface analysis carried out identify various bonds. frameworks for compounds constructed through based on energies know ascertain dominant involved contributing strength packing. Molecular studies indicated DBZIW had exhibits high binding affinity thyroid-stimulating hormone receptor (TSHR) protein targets (4QT5).

Language: Английский

Citations

0

Comprehensive Study of 1,2,4-Triazolo[1,5]Benzodiazepine Derivatives: Synthesis, Characterization, X-Ray Diffraction, DFT Calculations, Hirshfeld Surface Analysis, ADMET Properties, and Molecular Docking DOI

Marouane Ait Lahcen,

Driss Fadili, Walid Ettahiri

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 140410 - 140410

Published: Oct. 1, 2024

Language: Английский

Citations

2

Anticancer Effect of Novel Phthalazines Derivatives: Synthesis, Biological Evaluation, DFT, ADMET and Docking Study DOI
Walid Ettahiri, Driss Fadili, Mohammed M. Alanazi

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 141173 - 141173

Published: Dec. 1, 2024

Language: Английский

Citations

1

Synthesis, characterization, proteolytic activity inhibition, ADMET prediction, and molecular docking studies of novel indole derivatives as potential SARS-CoV-2 protease inhibitors DOI
Abdelali Chihab, Nabil El Brahmi, Abdelmoula El Abbouchi

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1323, P. 140707 - 140707

Published: Nov. 10, 2024

Language: Английский

Citations

0

Crystal structure and Hirshfeld surface analysis of N-(4-nitrophenyl)-2-(piperidin-1-yl)acetamide (lidocaine analogue) DOI Creative Commons
Imane Maimoune, Benson M. Kariuki, Abderrazzak El Moutaouakil Ala Allah

et al.

Acta Crystallographica Section E Crystallographic Communications, Journal Year: 2024, Volume and Issue: 81(1), P. 69 - 73

Published: Dec. 23, 2024

In the title molecule, C 13 H 17 N 3 O , substituents on phenyl ring are rotated slightly out of mean plane but piperidine moiety is nearly perpendicular to that plane. crystal, C—H...O hydrogen bonds form chains molecules extending along c -axis direction, which linked by C=O...π(ring) interactions. A Hirshfeld surface analysis showed majority intermolecular interactions be H...H contacts while O...H/H...O second most numerous.

Language: Английский

Citations

0