The
problem
of
microplastics
(MPs)
contamination
in
food
has
gradually
come
to
the
fore.
MPs
can
be
transmitted
through
chain
and
accumulate
within
various
organisms,
ultimately
posing
a
threat
human
health.
For
first
time,
we
compared
differences
toxicity
polyethylene
terephthalate
(PET),
polyvinyl
chloride
(PVC),
polystyrene
(PS)
nanoplastics
(NPs)
different
polymer
types
HepG2
cells
their
potential
toxic
mechanisms.
Common
polymers
PET,
PVC,
PS
NPs,
which
had
similar
particle
size,
surface
charge,
shape,
were
prepared
using
nanoprecipitation
emulsion
polymerization
successfully.
This
enabled
us
investigate
impact
on
cytotoxicity.
findings
demonstrated
that
high
concentrations
PET
PVC
NPs
trigger
cell
apoptosis
oxidative
stress,
but
did
not
have
same
harmful
impact.
Furthermore,
our
analysis
transcriptomics
data
revealed
significantly
reduced
expression
genes
related
bile
acid
metabolism
PPAR
signaling
pathway.
effect
may
lead
perturbation
cellular
lipid
metabolism.
resulted
higher
degree
down-regulation
these
NPs.
It
is
worth
noting
inhibit
cycle
DNA
repair-related
p53
pathway,
aggravating
damage
arresting
progression
by
inhibiting
repair.
constitute
principal
factor
accounting
for
variations
across
types.
These
comparative
studies
discoveries
regarding
molecular
mechanisms
provide
theoretical
basis
mitigating
health
risks
stemming
from
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: May 17, 2024
Abstract
Background
Nanoplastics,
are
emerging
pollutants,
present
a
potential
hazard
to
food
security
and
human
health.
Titanium
dioxide
nanoparticles
(Nano-TiO
2
),
serving
as
nano-fertilizer
in
agriculture,
may
be
important
alleviating
polystyrene
nanoplastics
(PSNPs)
toxicity.
Results
Here,
we
performed
transcriptomic,
metabolomic
physiological
analyzes
identify
the
role
of
Nano-TiO
regulating
metabolic
processes
PSNPs-stressed
maize
seedlings
(
Zea
mays
L.).
The
growth
inhibition
by
PSNPs
stress
was
partially
relieved
.
Furthermore,
when
considering
outcomes
obtained
from
RNA-seq,
enzyme
activity,
metabolite
content
analyses,
it
becomes
evident
that
significantly
enhance
carbon
nitrogen
metabolism
levels
plants.
In
comparison
plants
were
not
subjected
,
exposed
exhibited
enhanced
capabilities
maintaining
higher
rates
photosynthesis,
sucrose
synthesis,
assimilation,
protein
synthesis
under
stressful
conditions.
Meanwhile,
alleviated
oxidative
damage
modulating
antioxidant
systems.
Interestingly,
also
found
endogenous
melatonin
seedlings.
P
-chlorophenylalanine
p
-CPA,
inhibitor)
declined
-induced
tolerance.
Conclusions
Taken
together,
our
data
show
is
involved
promotion
through
regulation
metabolism.
Graphical
Environment International,
Journal Year:
2025,
Volume and Issue:
195, P. 109257 - 109257
Published: Jan. 1, 2025
Micro-and-nano
plastics
(MNPs)
are
pervasive
in
terrestrial
ecosystems
and
represent
an
increasing
threat
to
plant
health;
however,
the
mechanisms
underlying
their
phytotoxicity
remain
inadequately
understood.
MNPs
can
infiltrate
plants
through
roots
or
leaves,
causing
a
range
of
toxic
effects,
including
inhibiting
water
nutrient
uptake,
reducing
seed
germination
rates,
impeding
photosynthesis,
resulting
oxidative
damage
within
system.
The
effects
complex
influenced
by
various
factors
size,
shape,
functional
groups,
concentration.
Recent
advancements
omics
technologies
such
as
proteomics,
metabolomics,
transcriptomics,
microbiomics,
coupled
with
emerging
like
4D
omics,
phenomics,
spatial
single-cell
offer
unprecedented
insight
into
physiological,
molecular,
cellular
responses
exposure.
This
literature
review
synthesizes
current
findings
regarding
MNPs-induced
phytotoxicity,
emphasizing
alterations
gene
expression,
protein
synthesis,
metabolic
pathways,
physiological
disruptions
revealed
analyses.
We
summarize
how
interact
structures,
disrupt
processes,
induce
stress,
ultimately
affecting
growth
productivity.
Furthermore,
we
have
identified
critical
knowledge
gaps
proposed
future
research
directions,
highlighting
necessity
for
integrative
studies
elucidate
pathways
toxicity
plants.
In
conclusion,
this
underscores
potential
approaches
MNPs-phytotoxicity
develop
strategies
mitigating
environmental
impact
on
health.
Plants,
Journal Year:
2025,
Volume and Issue:
14(4), P. 528 - 528
Published: Feb. 9, 2025
Micro–nanomaterials
have
garnered
significant
attention
in
rice
(Oryza
sativa
L.)
cultivation
due
to
their
unique
physicochemical
properties.
This
study
reviews
the
multifunctional
applications
of
micro–nanomaterials
enhancing
resilience,
promoting
nutrient
uptake,
improving
photosynthetic
efficiency,
and
increasing
utilization
rates
fertilizers
pesticides.
Using
keyword
clustering
analyses,
this
review
identifies
key
research
hotspots
emerging
trends
field,
including
heavy
metal
stress,
nanoplastic
pollution,
biochar
applications.
While
early
studies
predominantly
focused
on
synthesis
characterization
these
materials,
recent
has
shifted
towards
evaluating
comprehensive
ecological
impacts
production
systems.
Despite
promising
potential
yield
quality
while
supporting
sustainable
agriculture,
concerns
about
long-term
accumulation
ecosystems
toxicity
remain
unresolved.
Future
should
prioritize
development
cost-effective,
efficient,
environmentally
friendly
establish
standardized
frameworks
for
risk
assessments
facilitate
large-scale
agricultural
application.
provides
theoretical
insights
practical
references
advancing
micro–nanotechnology
global
food
security
agriculture.
