Phytochemicals with anticancer activity from poisonous plants: potential leads for cancer therapy DOI

Eun Seo Jang,

Youngsang Nam,

Yeo Jin Lee

et al.

Phytochemistry Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 3, 2024

Language: Английский

Establishment of an efficient genetic transformation system and characterization of metabolic and transcriptomic landscapes of hairy roots in Syringa pinnatifolia DOI Creative Commons
Jiaqi Gao,

Linfan Zhang,

Luqi Huang

et al.

Scientia Horticulturae, Journal Year: 2025, Volume and Issue: 342, P. 114039 - 114039

Published: Feb. 1, 2025

Language: Английский

Citations

0

Cotton under heat stress: a comprehensive review of molecular breeding, genomics, and multi-omics strategies DOI Creative Commons

Tahira Luqman,

Manzoor Hussain,

Syed Riaz Ahmed

et al.

Frontiers in Genetics, Journal Year: 2025, Volume and Issue: 16

Published: March 18, 2025

Cotton is a vital fiber crop for the global textile industry, but rising temperatures due to climate change threaten its growth, quality and yields. Heat stress disrupts key physiological biochemical processes, affecting carbohydrate metabolism, hormone signaling, calcium gene regulation expression. This review article explores cotton's defense mechanism against heat stress, including epigenetic regulations transgenic approaches, with focus on genome editing tools. Given limitations of traditional breeding, advanced omics technologies such as GWAS, transcriptomics, proteomics, ionomics, metabolomics, phenomics CRISPR-Cas9 offer promising solutions developing heat-resistant cotton varieties. highlights need innovative strategies ensure sustainable production under change.

Language: Английский

Citations

0

A Comprehensive Analysis of Transcriptomics and Metabolomics Reveals Key Genes Involved in Terpenes Biosynthesis Pathway of Litsea cubeba Under Light and Darkness Treatments DOI Open Access
Jiahui Yang, Yunxiao Zhao, Yicun Chen

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 2992 - 2992

Published: March 25, 2025

Light is an important environmental regulator of plant secondary metabolism. Terpenoids, the most abundant metabolites in plants, demonstrate a wide spectrum biologically significant properties, encompassing antimicrobial, antioxidative, and analgesic activities. Litsea cubeba (Lour.) Pers., core species within Lauraceae family, exhibits notable pharmacological potential, including antimicrobial antitumor effects. Here, we found that darkness treatment significantly suppressed terpenoid accumulation L. fruits. To clarify molecular mechanisms underlying regulatory effect light treatments on biosynthesis, conducted comparative transcriptome profiling fruits under treatments. A total 13,074 differentially expressed genes (DEGs) were identified among four sampling time points (L1-L2-L3-L4 vs. D1-D2-D3-D4). These enriched various pathways, with enrichment being observed other metabolism pathways. Additionally, DEGs L2 D2 stages was further studied, it nine monoterpene synthesis pathway. The weighted gene co-expression network analysis (WGCNA) showed alcohol dehydrogenase (ADH), key enzyme synthesis, had same expression pattern as WRKY NAC transcription factors, suggesting their involvement biosynthesis terpenoids cubeba. Expression demonstrated plastid-localized pathway markedly downregulated treatment. qRT-PCR validation (LcDXS3, LcHMGS1, LcMDS, LcTPS19) confirmed reliability data, LcDXS3 exhibiting pronounced declines after 6 h (2.76-fold decrease) 12 (2.63-fold findings provide novel insights into photoregulatory governing

Language: Английский

Citations

0

Current insights into plant volatile organic compound biosynthesis DOI
Lin Chen, Pan Liao

Current Opinion in Plant Biology, Journal Year: 2025, Volume and Issue: 85, P. 102708 - 102708

Published: March 28, 2025

Language: Английский

Citations

0

Non-canonical plant metabolism DOI
Lee Sweetlove, R. George Ratcliffe, Alisdair R. Fernie

et al.

Nature Plants, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

Language: Английский

Citations

0

Discovery and Engineering of the Asiaticoside, Madecassoside and Asiaticoside B Biosynthetic Pathway DOI
Peina Zhou, Peng Yang,

Kaiwei Zhang

et al.

Plant Physiology and Biochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 109864 - 109864

Published: April 1, 2025

Language: Английский

Citations

0

Discovery and characterisation of terpenoid biosynthesis enzymes from Daphniphyllum macropodum DOI Creative Commons
Kaouthar Eljounaidi,

Caragh Whitehead,

Elizabeth Radley

et al.

BMC Plant Biology, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 16, 2025

Language: Английский

Citations

0

Recent advances in the biosynthesis of natural products from C1 compounds DOI
Xinzhe Zhang, Aipeng Li,

Xiaohan Huang

et al.

Chinese Journal of Chemical Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0

Research Progress of Genomics Applications in Secondary Metabolites of Medicinal Plants: A Case Study in Safflower DOI Open Access
Zhihua Wu,

Yan Na Hu,

Rui Hao

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(8), P. 3867 - 3867

Published: April 19, 2025

Medicinal plants, recognized as significant natural resources, have gained prominence in response to the increasing global demand for herbal medicines, necessitating large-scale production of these plants and their derivatives. are exposed a variety internal external factors that interact influence biosynthesis accumulation secondary metabolites. With rapid development omics technologies such genomics, transcriptomics, proteomics, metabolomics, multi-omics become important tools revealing complexity functionality organisms. They conducive further uncovering biological activities metabolites medicinal clarifying molecular mechanisms underlying Also, artificial intelligence (AI) technology accelerates comprehensive utilization high-dimensional datasets offers transformative potential analysis. However, there is currently no systematic review summarizing genomic metabolite plants. Safflower (Carthamus tinctorius L.) has rich diverse bioactive flavonoids, among which Hydroxysafflor yellow A (HSYA) specific safflower emerging medication treating wide range diseases. Hence, progress been made study an excellent example regulation recent years. Here, we on understanding main at level, summarize various types contents, with particular focus flavonoids. This aims provide insight into regulatory from perspective genomics.

Language: Английский

Citations

0

CbCBF2 Integrates JA and BR Signaling to Enhance Oleanolic Acid Biosynthesis in Conyza blinii H. Lév Under Cold Stress DOI Creative Commons
Ming Yang, Guodong Zhang, Junjie Deng

et al.

Agronomy, Journal Year: 2025, Volume and Issue: 15(5), P. 1001 - 1001

Published: April 22, 2025

Low temperature significantly contributes to the medicinal quality of Conyza blinii. The CBF/DREB1-dependent cold-responsive signaling pathway is a major contributor plant cold stress resistance. However, whether CBF/DREB1 affects terpenoid metabolism C. blinii under remains be explored. Here, we systematically identified and analyzed impact CbCBFs on results showed that three CbICE1 were based transcriptome. functions correlated with encompass hormones responses. Co-expression analysis revealed key genes in BR JA pathways CbCBFs. Among them, CbCBF2 predominant factor low-temperature conditions positively oleanolic acid. Overexpression upregulated catalase gene CbβAS increased acid content leaves. These indicate can act as regulatory promote synthesis by integrating low conditions.

Language: Английский

Citations

0