Polyelectrolytes and Polyelectrolyte Complexes as Future Antibacterial Agents DOI Creative Commons

Rahaf Alsayyed,

Adriana Ribeiro,

Helena Cabral-Marques

et al.

Bacteria, Journal Year: 2024, Volume and Issue: 3(4), P. 452 - 475

Published: Dec. 3, 2024

Antibiotic-resistance (ABR) poses a critical public health challenge within the broader antimicrobial resistance crisis. This review evaluates potential of polyelectrolytes (PEs) and polyelectrolyte complexes (PECs) for controlled antibiotic delivery as strategy to combat ABR biofilm-related infections. PECs, particularly those incorporating chitosan other polycations, enhance antibacterial efficacy by disrupting bacterial cell walls obstructing their nutrient flow. They are also effective in penetrating biofilms providing sustained drug release. Despite these advantages, there is need further vivo research clinical trials validate findings. provides comprehensive overview PECs’ advance therapies outlines future directions explore applications.

Language: Английский

Layer-by-Layer Nanoarchitectonics: A Method for Everything in Layered Structures DOI Open Access
Katsuhiko Ariga

Materials, Journal Year: 2025, Volume and Issue: 18(3), P. 654 - 654

Published: Feb. 1, 2025

The development of functional materials and the use nanotechnology are ongoing projects. These fields closely linked, but there is a need to combine them more actively. Nanoarchitectonics, concept that comes after nanotechnology, ready do this. Among related research efforts, into creating through formation thin layers on surfaces, molecular membranes, multilayer structures these have lot implications. Layered especially important as key part nanoarchitectonics. diversity components used in layer-by-layer (LbL) assemblies notable feature. Examples LbL introduced this review article include quantum dots, nanoparticles, nanocrystals, nanowires, nanotubes, g-C3N4, graphene oxide, MXene, nanosheets, zeolites, nanoporous materials, sol–gel layered double hydroxides, metal–organic frameworks, covalent organic conducting polymers, dyes, DNAs, polysaccharides, nanocelluloses, peptides, proteins, lipid bilayers, photosystems, viruses, living cells, tissues. examples assembly show how useful versatile it is. Finally, will consider future challenges

Language: Английский

Citations

2
Chitosan Edible Coatings Loaded with Bioactive Components for Fruits and Vegetables: A Step Toward Sustainable Development Goals DOI

­ Sapna,

Chhavi Sharma, Puneet Pathak

et al.

Food and Bioprocess Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 7, 2025

Language: Английский

Citations

1
Enhancing the Hydrophobicity of Chitosan Films Through Hierarchical Plant Wax Particles and Dilute Chitosan Solution Coatings DOI Creative Commons
Chengcheng Gao, Ni Zhang, Ying Chen

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(4), P. 610 - 610

Published: Feb. 12, 2025

The strong hydrophilicity of chitosan-based films limits their practical applications. To enhance the hydrophobicity these films, hierarchical carnauba wax particles were prepared using Pickering emulsion method and subsequently coated onto film surfaces. was stabilized with various types concentrations TiO2. resulting exhibited a micro-scale structure, nano-scale TiO2 aggregates present on surface. No significant differences in contact angle observed among particles. Hydrophilic demonstrated smaller sliding angles particle sizes. improve mechanical durability compatibility chitosan matrix, mixed diluted solution before coating. As concentration increased decreased, more became exposed This exposure roughness coatings, increase decrease angle. A high provided greater protection to during tests. Additionally, residue rate liquid foods coating significantly decreased. study demonstrates that is an effective approach for preparing particles, mixing polymer similar matrix can effectively durability.

Language: Английский

Citations

0
Biopolymers from Sugar Beet Molasses: Isolation, Characterization, and Bioactive Properties DOI Creative Commons

J. D. Crouse,

Stephen G. Sellers,

Karen Wawrousek

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Utilizing the natural biological properties of plant byproducts for a variety applications presents opportunity to combine nature's benefits with sustainable innovation. For this study, sugar beet molasses polymer (SBMP) was isolated from byproduct processing. The SBMP analyzed determine its suitability potential uses in biomedicine, cosmetics, and antimicrobial coatings. To whether indeed polymer, MALDI-TOF MS performed. chemical composition characterized using XPS, 1H NMR, 13C FTIR. characterization concluded that contains phenolic hydroxide groups. presence these groups further supported by SBMP's high antioxidant activity (∼80% RSA). also demonstrated against Rhodococcus erythropolis GI at 1 mg/mg SBMP), Escherichia coli Saccharomyces cerevisiae (∼38% SBMP). Additionally, showed no toxicity human adipose-derived stem cells (ADSC) concentrations up 0.5 mg/mL healthy cellular growth. Due strong activity, could be used biomedical, cosmetic, coating applications.

Language: Английский

Citations

0
Ultra-Pressurized Deposition of Hydrophobic Chitosan Surface Coating on Wood for Fungal Resistance DOI Open Access
Suelen P. Facchi, Débora Aparecida de Almeida, Karen Keli Barbosa Abrantes

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(20), P. 10899 - 10899

Published: Oct. 10, 2024

Fungi (

Language: Английский

Citations

2
Polyelectrolytes and Polyelectrolyte Complexes as Future Antibacterial Agents DOI Creative Commons

Rahaf Alsayyed,

Adriana Ribeiro,

Helena Cabral-Marques

et al.

Bacteria, Journal Year: 2024, Volume and Issue: 3(4), P. 452 - 475

Published: Dec. 3, 2024

Antibiotic-resistance (ABR) poses a critical public health challenge within the broader antimicrobial resistance crisis. This review evaluates potential of polyelectrolytes (PEs) and polyelectrolyte complexes (PECs) for controlled antibiotic delivery as strategy to combat ABR biofilm-related infections. PECs, particularly those incorporating chitosan other polycations, enhance antibacterial efficacy by disrupting bacterial cell walls obstructing their nutrient flow. They are also effective in penetrating biofilms providing sustained drug release. Despite these advantages, there is need further vivo research clinical trials validate findings. provides comprehensive overview PECs’ advance therapies outlines future directions explore applications.

Language: Английский

Citations

1