Novel Aminocoumarin‐Based Schiff Bases: High Antifungal Activity in Agriculture DOI
Xin Zhang, Ming Gao, Yajie Dong

et al.

Chemistry & Biodiversity, Journal Year: 2024, Volume and Issue: 21(12)

Published: Aug. 22, 2024

Abstract Structural modification is an effective way to improve the antifungal activity of natural products and has been widely used in development novel fungicides. In this work, a series aminocoumarin‐based Schiff bases were synthesized characterized by 1 H‐NMR, 13 C NMR HR‐MS spectra. The vitro inhibition all compounds was tested against four phytopathogenic fungi ( Alternaria solani , Fusarium oxysporum Botrytis cinerea alternata ) using mycelial growth rate method. results showed that most target exhibited significant activities. particular, 5b 5c 5d 5h 5n 7c 7n 7p more than commercially available fungicides, chlorothalonil azoxystrobin. structure‐activity relationship revealed electron‐withdrawing groups with electronegativity introduced at C‐3 position improving inhibitory halogenated benzaldehydes would be necessary preparation bases. compound (EC 50 =8.73 μg/mL) =26.25 much better positive controls (chlorothalonil azoxystrobin). Therefore, could serve as promising lead for broad‐spectrum which useful applications agriculture.

Language: Английский

Antifungal activity of 2-decanone against Monilinia fructicola and its application in combination with boscalid in mitigating brown rot disease in peach fruit DOI
Xiaorui Wang, Mingming Huang, Wenhui Li

et al.

Physiological and Molecular Plant Pathology, Journal Year: 2025, Volume and Issue: unknown, P. 102665 - 102665

Published: March 1, 2025

Language: Английский

Citations

0
Chemical Composition, Antifungal Activity, and Plant-Protective Potential of Rosa damascena Mill. Essential Oil Against Fusarium graminearum DOI Creative Commons
Esma Özsoy, Timur Hakan Barak, Emre Yörük

et al.

Pathogens, Journal Year: 2025, Volume and Issue: 14(4), P. 383 - 383

Published: April 15, 2025

Fusarium graminearum is a common plant pathogen among cereals worldwide. The application of chemical antifungal compounds the most frequently used method in controlling F. graminearum. However, its excessive use and genomic plasticity fungal genome lead to increased resistance levels these compounds. In this context, plant-derived might play role protecting against head blight (FHB) crown rot (CR) as an alternative. study, we aimed examine effects essential oil obtained from Rosa damascena Mill. on using molecular analytical methods. composition was determined by GC-MS. half effective concentration (EC50) value R. (REO) for 604.25 µg mL−1. Water-soluble tetrazolium 1 (WST-1) analyses revealed that REO caused cytotoxicity potential oxidative stress autophagic cell death capacity towards via gene expression analysis fluorescence microscopy. It also that, due plant-protective effect REO, disease severity treated plants decreased up 27.78% juvenile wheat seedlings infected Our data show be alternative natural ingredient field protection.

Language: Английский

Citations

0
Protecting anthocyanins of postharvest blueberries through konjac glucomannan/low-acyl gellan gum coatings contained thymol microcapsule during low-temperature storage DOI

Jing Xie,

Dur E. Sameen,

Zhenkun Xiao

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 463, P. 141347 - 141347

Published: Sept. 17, 2024

Language: Английский

Citations

3
Honokiol inhibits Botryosphaeria dothidea, the causal pathogen of kiwifruit soft rot, by targeting membrane lipid biosynthesis DOI
Zhuzhu Zhang, Tingting Chen, Xianhui Yin

et al.

Pest Management Science, Journal Year: 2023, Volume and Issue: 80(4), P. 1779 - 1794

Published: Nov. 30, 2023

Kiwifruit soft rot is mainly caused by Botryosphaeria dothidea, representing a considerable threat to kiwifruit industry. This investigation assessed the inhibitory consequences and mechanisms of honokiol against B. evaluating effects underlying mechanism.

Language: Английский

Citations

8
Inhibitory effects and mechanisms of cinnamaldehyde against Fusarium oxysporum, a serious pathogen in potatoes DOI
Chunlin Zhang,

Hongling Liu,

Xue Wang

et al.

Pest Management Science, Journal Year: 2024, Volume and Issue: 80(7), P. 3540 - 3552

Published: March 6, 2024

Abstract BACKGROUND Potatoes, a major economic crop, are significantly impacted by Fusarium dry rot, prevalent postharvest disease. Despite the broad‐spectrum antimicrobial properties of cinnamaldehyde, naturally‐derived plant substance, its efficacy against causal pathogen potato rot ( oxysporum ) and underlying mechanisms have not been extensively studied. RESULTS Our study demonstrates that cinnamaldehyde effectively inhibits growth , responsible for increases sensitivity to environmental stress factors such as extreme temperatures high salt stress. Treatment with results in altered fungal mycelium morphology, compromised cell wall stability, disrupted membrane integrity, thereby reducing spore viability. Specifically, it interferes structures fungus, potentially disrupting modulating signaling pathways involved maintenance, chitin metabolism, GPI‐anchored protein function. Notably, we show induces form regulated death F. which is characterized typical apoptosis, evidenced Annexin V negative staining. However, specific type mechanism still needed be further explored. CONCLUSION Cinnamaldehyde, an environmentally friendly plant‐based active compound, exhibits strong inhibitory effects on indicating potential use prevention control strategies rot. This research contributes understanding novel antifungal offers promising insights into eco‐friendly alternatives managing this economically significant © 2024 Society Chemical Industry.

Language: Английский

Citations

2
In vitro control of Fusarium oxysporum f. sp. lycopersici Race 3 by the innovative formulation consisting of a thymol-based emulsion, and evaluation of its effects on the vigor of tomato seeds DOI

Luan Rezende Peccini,

Walter Cesar Celeri Bigui,

Bianca de Oliveira Botelho

et al.

Scientia Horticulturae, Journal Year: 2024, Volume and Issue: 336, P. 113380 - 113380

Published: June 12, 2024

Language: Английский

Citations

2
Design, synthesis and biological activity evaluation of eco‐friendly rosin‐based fungicides for sustainable crop protection DOI

Renle Xu,

Yue Kong,

Yuhang Lou

et al.

Pest Management Science, Journal Year: 2024, Volume and Issue: 80(11), P. 5898 - 5908

Published: July 19, 2024

Utilizing fungicides to protect crops from diseases is an effective method, and novel eco-friendly plant-derived with high efficiency low toxicity are urgent requirements for sustainable crop protection.

Language: Английский

Citations

2
Discovery of natural rosin-based preservative candidates to control Phytophthora capsici for postharvest disease management of solanaceae vegetables DOI

Renle Xu,

Jiaying Wu, Han Xu

et al.

Postharvest Biology and Technology, Journal Year: 2024, Volume and Issue: 218, P. 113133 - 113133

Published: Aug. 7, 2024

Language: Английский

Citations

2
Thymol Edible Coating Controls Postharvest Anthracnose by Regulating the Synthesis Pathway of Okra Lignin DOI Creative Commons
Qinqiu Zhang, Zhuwei Wang, Yinglu Li

et al.

Foods, Journal Year: 2023, Volume and Issue: 12(2), P. 395 - 395

Published: Jan. 13, 2023

Okra has received extensive attention due to its high nutritional value and remarkable functional characteristics, but postharvest diseases have severely limited application. It is important further explore the methods potential control of okra. In this study, Colletotrichum fioriniae major pathogen that causes okra anthracnose, which can be isolated from naturally decaying The pathogenicity C. against was preliminarily verified, related biological characteristics were explored. At same time, an observational study conducted investigate in vitro antifungal effect thymol edible coating (TKL) on fioriniae. After culturing at 28 °C for 5 days, it found TKL showed obvious growth inhibition concentration 50% maximal 95.10 mg/L, minimum inhibitory 1000 mg/L. addition, with a 100 mg/L (TKL100) may cause different degrees damage cell membrane, wall, metabolism fioriniae, thereby inhibiting hyphae causing hyphal rupture. Refer results bacteriostatic experiment. Furthermore, sprayed TKL100. TKL100 could significantly inhibit infection okra, reduce rate brown spots fold surface, mycelium growth. contents total phenols flavonoids treated higher than those group. Meanwhile, activities phenylalaninammo-nialyase, cinnamic acid-4-hydroxylase, 4-coumarate-CoA ligase lignin synthesis pathway generally increased, especially after 6 days incubator. content TKL-W highest, reaching 65.62 ± 0.68 mg/g, 2.24 times CK-W. Therefore, promote then stimulate activity key enzymes pathway, finally regulate Thus, certain controlling anthracnose.

Language: Английский

Citations

6
Anti‐oomycete ability of scopolamine against Phytophthora infestans, a terrible pathogen of potato late blight DOI
Zhiming Zhu,

Ziwen Xiong,

Wenjin Zou

et al.

Journal of the Science of Food and Agriculture, Journal Year: 2023, Volume and Issue: 103(13), P. 6416 - 6428

Published: May 20, 2023

Phytophthora infestans causes late blight, threatening potato production. The tropane alkaloid scopolamine from some industrial plants (Datura, Atropa, etc.) has a broad-spectrum bacteriostatic effect, but its effect on P. is unknown.In the present study, inhibited mycelial growth of phytopathogenic oomycete infestans, and half-maximal inhibitory concentration (IC50 ) was 4.25 g L-1 . sporangia germination rates were 61.43%, 16.16%, 3.99% at concentrations zero (control), 0.5 IC50 , respectively. viability significantly reduced after treatment through propidium iodide fluorescein diacetate staining, speculating that destroyed cell membrane integrity. detached tuber experiment demonstrated lessened pathogenicity in tubers. Under stress conditions, showed good inhibition indicating could be used multiple adverse conditions. combination chemical pesticide Infinito more effective than use or alone. Moreover, transcriptome analysis suggested leaded to downregulation most genes, functioning growth, metabolism, pathogenicity.To our knowledge, this first study detect activity against infestans. Also, findings highlight potential as an eco-friendly option for controlling blight future. © 2023 Society Chemical Industry.

Language: Английский

Citations

6