Advancements in Ischemic Stroke Management: Transition from Traditional to Nanotechnological Approaches
Mohammad Adil,
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Umme Jiba,
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Afshan Khan
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et al.
Journal of Drug Delivery Science and Technology,
Journal Year:
2024,
Volume and Issue:
unknown, P. 106318 - 106318
Published: Oct. 1, 2024
Language: Английский
Liver-Targeted Nanoparticles Loaded with Cannabidiol Based on Redox Response for Effective Alleviation of Acute Liver Injury
Xuan Zhang,
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Xiangzhou Yi,
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Xia Gao
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et al.
Foods,
Journal Year:
2024,
Volume and Issue:
13(15), P. 2464 - 2464
Published: Aug. 4, 2024
The
purpose
of
this
work
was
to
construct
liver-targeted
nanoparticles
based
on
the
redox
response
effectively
deliver
cannabidiol
(CBD)
for
prevention
acute
liver
injury
(ALI).
CBD-loaded
(CBD
NPs)
with
a
particle
size
126.5
±
1.56
nm
were
prepared
using
polymer
DA-PP-LA
obtained
by
grafting
pullulan
polysaccharide
deoxycholic
acid
(DA)
and
α-lipoic
(α-LA).
CBD
NPs
showed
typical
redox-response
release
behavior.
Interestingly,
exhibited
admirable
targeting
ability,
significantly
accumulated
in
liver,
promoted
internalization
cells,
thus
reducing
H
Language: Английский