International Journal of Community Medicine and Public Health, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 24, 2025

Peri-implantitis is a multifactorial condition characterized by inflammation and progressive bone loss surrounding dental implants, often leading to implant failure. High-risk populations, including patients with systemic conditions such as diabetes or undergoing cancer treatments, face an elevated susceptibility due impaired immune responses altered metabolism. Understanding the pathophysiological mechanisms underlying disease essential for effective risk assessment management. Dysbiosis of microbial biofilm, system dysregulation, factors like oxidative stress cytokine imbalances are critical contributors progression. These necessitate development targeted strategies prevention intervention. Risk models have evolved include advanced technologies artificial intelligence decision tree regression predict peri-implantitis in vulnerable individuals accurately. tools incorporate systemic, local, implant-specific parameters enable personalized treatment planning early Innovative management also emerged, ranging from adjunctive antimicrobial therapies, glycine powder air-polishing localized drug delivery systems, host modulation therapies regenerative techniques. The use biomaterials, implants coated bioactive peptides nanoparticles, has further improved osseointegration reduced infection rates. Regenerative approaches, application growth platelet-derived factor morphogenetic proteins, shown significant potential repairing peri-implant defects restoring functional stability. Emerging technologies, nanotechnology bioengineered offer new possibilities real-time health monitoring sustained therapeutic at sites. advancements, coupled deeper understanding etiology, provide framework optimizing outcomes high-risk addressing both local challenges posed disease.

Language: Английский