Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer’s disease DOI
Nourhan M. Abdelmaksoud, Al-Aliaa M. Sallam, Ahmed I. Abulsoud

et al.

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 253, P. 155007 - 155007

Published: Dec. 4, 2023

Language: Английский

miRNAs as cornerstones in chronic lymphocytic leukemia pathogenesis and therapeutic resistance– An emphasis on the interaction of signaling pathways DOI
Ahmed S. Doghish, Ahmed I. Abulsoud, Shereen Saeid Elshaer

et al.

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 243, P. 154363 - 154363

Published: Feb. 8, 2023

Language: Английский

Citations

57
miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay DOI
Shereen Saeid Elshaer, Ahmed I. Abulsoud, Doaa Fathi

et al.

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 246, P. 154511 - 154511

Published: May 9, 2023

Language: Английский

Citations

56
Decoding hepatocarcinogenesis from a noncoding RNAs perspective DOI
Mostafa K. Abd El‐Aziz, Alyaa Dawoud, Caroline Joseph Kiriacos

et al.

Journal of Cellular Physiology, Journal Year: 2023, Volume and Issue: 238(9), P. 1982 - 2009

Published: July 14, 2023

Abstract Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular carcinoma (HCC) has gained lot interest. Yet, underlying mechanistic basis liver tumorigenesis is poorly understood. The role some coding genes and their respective translated proteins, then later on, noncoding RNAs (ncRNAs) such as microRNAs have been extensively studied in context HCC pathophysiology; however, implication long (lncRNAs) circular (circRNAs) indeed less investigated. As subclass ncRNAs which elusive for time ago, lncRNAs was found to be involved plentiful cellular functions DNA, RNA, proteins regulation. Hence, it undisputed that dysregulation profoundly contributes via diverse etiologies. Accordingly, represent hot research topic requires prime focus HCC. In this review, authors discuss breakthrough discoveries involving circRNAs contributed contemporary concepts how these could leveraged potential novel diagnostic prognostic biomarkers. Further, review article sheds light on future trends, thereby discussing pathological roles proliferation, migration, epithelial‐to‐mesenchymal transition. Along line reasoning, recommendations targets exploited achieve effective HCC‐related drug development highlighted.

Language: Английский

Citations

56
miRNAs as potential game-changers in head and neck cancer: Future clinical and medicinal uses DOI
Hesham A. El-Mahdy,

Ahmed M. Mohamadin,

Ahmed I. Abulsoud

et al.

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 245, P. 154457 - 154457

Published: April 10, 2023

Language: Английский

Citations

51
The role of miRNAs in laryngeal cancer pathogenesis and therapeutic resistance – A focus on signaling pathways interplay DOI
Maghawry Hegazy, Mohamed A. Elkady,

Amr Mohamed Yehia

et al.

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 246, P. 154510 - 154510

Published: May 8, 2023

Language: Английский

Citations

47
The interplay of signaling pathways and miRNAs in the pathogenesis and targeted therapy of esophageal cancer DOI
Ahmed S. Doghish, Ahmed A. El-Husseiny, Nourhan M. Abdelmaksoud

et al.

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 246, P. 154529 - 154529

Published: May 11, 2023

Language: Английский

Citations

45
miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses DOI
Ahmed S. Doghish, Hebatallah Ahmed Mohamed Moustafa, Mohammed S. Elballal

et al.

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 247, P. 154537 - 154537

Published: May 19, 2023

Language: Английский

Citations

41
Revealing the role of serum exosomal novel long non-coding RNA NAMPT-AS as a promising diagnostic/prognostic biomarker in colorectal cancer patients DOI

Nehal I. Rizk,

Dina H. Kassem, Ahmed I. Abulsoud

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: 352, P. 122850 - 122850

Published: June 18, 2024

Language: Английский

Citations

17
Unraveling the ncRNA landscape that governs colorectal cancer: A roadmap to personalized therapeutics DOI
Nadia Μ. Hamdy, Mohamed Bakr Zaki,

Nehal I. Rizk

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: 354, P. 122946 - 122946

Published: Aug. 8, 2024

Language: Английский

Citations

17
LncRNA NNT-AS1/hsa-miR-485–5p/HSP90 axis in-silico and clinical prospect correlated-to histologic grades-based CRC stratification: A step toward ncRNA Precision DOI

Nada M. El-Sheikh,

Ahmed I. Abulsoud, Amal Fawzy

et al.

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 247, P. 154570 - 154570

Published: May 24, 2023

Language: Английский

Citations

41