Morchella conica, Morchella esculenta and Morchella delicosa Induce Apoptosis in Breast and Colon Cancer Cell Lines via Pro-apoptotic and Anti-apoptotic Regulation DOI
Faiz Ul Haq, Muhammad Imran, Sami Ullah

et al.

Chinese Journal of Integrative Medicine, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 3, 2024

Language: Английский

An Introduction to Recent Approaches Underlying Mechanistic Insights Harboring Oncobiology DOI
R. C. Sobti, Aastha Sobti

Published: Jan. 1, 2024

Language: Английский

Citations

1
Discovery of Structural Diversity Guided N‐S Heterocyclic Derivatives Based on Natural Benzothiazole Alkaloids as Potential Cytotoxic Agents DOI

Lirong Guo,

Yafei Wan,

Manli Liu

et al.

Journal of Heterocyclic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 16, 2024

ABSTRACT Benzothiazole alkaloids are a class of rare heterocyclic with unique structures and exhibit wide range biological activities. So, the aim this work is to investigate structural diversity‐guided N‐S derivatives based on natural benzothiazole as potential cytotoxic agents. Three series novel derivatives, including 22 compounds, were designed synthesized using pharmacophore hybridization, their in vitro activities against Huh‐7 A875 fully evaluated. The results indicated that some these had significantly good two tested cell lines compared positive control 5‐fluorouracil, other compounds 3f–3i displayed selectivity between lines, which might be used promising lead molecule for discovery benzothiazole‐type

Language: Английский

Citations

1
Editorial: Non-cellular immunotherapies in pediatric malignancies DOI Creative Commons
Sarah Alexander, Paul Harker‐Murray, Robert J. Hayashi

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Feb. 21, 2024

Citation: Alexander S, Harker-Murray P and Hayashi RJ (2024) Editorial: Non-cellular immunotherapies in pediatric malignancies. Front. Immunol. 15:1379278. doi: 10.3389/fimmu.2024.1379278

Language: Английский

Citations

0
Therapeutic Approaches to Immunotherapy Induced Chronic Inflammatory Diseases DOI Creative Commons

Emmanuel Adebola Adebanjo,

Kafayat Motomori Bakare, Ugochukwu Okwudili Matthew

et al.

Journal of Science, Management and Technology, Journal Year: 2024, Volume and Issue: 5(2), P. 144 - 159

Published: May 9, 2024

The development of immunotherapy vaccines hinges on the identification suitable biomarkers and optimization treatment combinations to enhance their efficacy in patients. Over past few decades, research has advanced, leading availability numerous defined vaccinations. Still unsolved are a issues, such as appropriate tumor antigen, adjuvant components for chronic inflammatory diseases, delivery mechanisms, efficient strategies fend off immunological attacks. term diseases (CID) refers group illnesses which immune system is unable control typical acute inflammation, resulting an ongoing, unresolved state inflammation. Conditions including psoriasis, bowel disease, rheumatoid arthritis affect considerable number people globally, making CID substantial burden global healthcare systems. Conventional therapies frequently relieve symptoms, but they may also have serious adverse effects be ineffective. By focusing dysregulated responses that underlie illnesses, become viable option. With focus important therapeutic approaches, mechanisms action, clinical efficacy, safety profiles, this paper offers extensive assessment immunotherapy-induced treatments illnesses. Furthermore, addresses present conundrums potential paths forward creation enhancement immunotherapeutic crippling ailments.

Language: Английский

Citations

0
Morchella conica, Morchella esculenta and Morchella delicosa Induce Apoptosis in Breast and Colon Cancer Cell Lines via Pro-apoptotic and Anti-apoptotic Regulation DOI
Faiz Ul Haq, Muhammad Imran, Sami Ullah

et al.

Chinese Journal of Integrative Medicine, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 3, 2024

Language: Английский

Citations

0