Effect of enrofloxacin on clinical parameters and mucociliary system of broilers challenged with H9N2 avian influenza/infectious bronchitis viruses DOI Creative Commons
Mohammad Abbasnia, Najmeh Mosleh, H. Dadras

et al.

Veterinary Medicine and Science, Journal Year: 2024, Volume and Issue: 10(2)

Published: Feb. 28, 2024

Abstract Background Effect of antibacterials on mucociliary system and clinical outcome chickens with mixed viral respiratory conditions is not properly addressed. Objective We evaluated enrofloxacin effects parameters broilers challenged H9N2/IB viruses. Methods Broilers (105), at the age 25 days, were randomly allocated into three groups: Group 1 (negative control), no treatment; 2 (positive control [PC]) by intranasal intraocular route. 3 (antibiotic [AB]‐treated) also received started after manifestation signs (day post‐challenge [pc]) continued for 5 days. Results Administration AB was associated appreciable changes in body weight, feed conversion ratio (FCR) or severity although it slightly reduced mortality rate as compared to PC group ( p > 0.05). Virus shedding period number virus positive tracheal caecal tonsil samples statistically similar between groups. In necropsy, most profound effect decreased pleuropneumonia score day 12 pc. Histopathological lesion scores same However, administration increased goblet cells, ciliostasis. Conclusions found a weak H9N2/IB‐infected chickens. Considering risks treatment broiler chickens, results this small‐scale study do encourage benefit use these diseases.

Language: Английский

Infectious Bronchitis Virus (IBV) in Vaccinated and Non-Vaccinated Broilers in Brazil: Surveillance and Persistence of Vaccine Viruses DOI Creative Commons

Gleidson Biasi Carvalho Salles,

Giulia Von Tönnemann Pilati, Beatriz Pereira Savi

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(3), P. 521 - 521

Published: Feb. 27, 2025

Infectious bronchitis virus (IBV) poses a significant threat to poultry worldwide, necessitating robust surveillance and vaccination strategies. This study aimed conduct IBV in Brazil, assess potential vaccine viral escapes, evaluate persistence vaccinated broilers. A total of 1000 tracheal swabs from 100 flocks across six states were analyzed using RT-PCR. The results showed that 91% the tested positive for IBV. detected strains included GI-1, GI-11, GI-23. Notably, 90% batches received vaccines containing either GI-1 or GI-11 lineages. revealed 67 samples between days 16 32 post-vaccination. In contrast, unvaccinated had high prevalence (70%). These findings highlight widespread circulation Brazil with persistent presence birds wild viruses ones. Collectively, data reveal characterized by prolonged animals occurrence both those against specific strains. It can be concluded this there was providing long animals, as well individual

Language: Английский

Citations

1
Surveillance of Escherichia coli in different types of chicken and duck hatcheries: one health outlook DOI Creative Commons

Hend M. Y. Yousef,

Mahmoud Hashad,

Kamelia M. Osman

et al.

Poultry Science, Journal Year: 2023, Volume and Issue: 102(12), P. 103108 - 103108

Published: Sept. 13, 2023

Escherichia coli is an important zoonotic bacterium that significantly impacts one health concept. E. normally detected in the gut of warm-blooded animals, but some serotypes can cause diseases humans and animals. Moreover, it continue for a long time different environments, replicate water, survive outside hosts. In this study, 171 samples collected from 10 types poultry hatcheries (automatic, semiautomatic, manual "traditional" types) were examined prevalence coli. PCR was applied to verify isolates via 16S rRNA gene-specific primers. From gathered samples, 62 recovered (36.3%). The highest met with (57.1%) no significance difference (P = 0.243) 3 hatcheries. incidence varied tested avian breeds. 35.7% duck 37% chicken hatcheries, significant differences between breeds both species 0.024 0.001, respectively). identification study concerning, highlighting need collaborative efforts across various sectors, including social, environmental, governance, promote adoption principle business. Periodical surveillance, biosecurity measures at farm levels, boosting immunity birds recommended limit risk spread sources humans.

Language: Английский

Citations

17
Ameliorative avian gut environment and bird productivity through the application of safe antibiotics alternatives: a comprehensive review DOI Creative Commons
Heba M. Salem, Ahmed M. Saad, Soliman M. Soliman

et al.

Poultry Science, Journal Year: 2023, Volume and Issue: 102(9), P. 102840 - 102840

Published: June 13, 2023

The avian digestive tract is an important system for converting ingested food into the nutrients their bodies need maintenance, growth, and reproduction (meat, table eggs, fertile eggs). Therefore, preserving integrity crucial to bird health productivity. As alternative antibiotics, world has recently turned use of natural products enhance development, intestinal health, production. primary goal this review explain various characteristics how its performance with natural, safe feed additives such as exogenous enzymes, organic acids, photogenic products, amino prebiotics, probiotics, synbiotics, herbal extracts. In conclusion, composition gut microbiome can be influenced by a number circumstances, consequences productivity birds. To better understand connection between pathogens, variety therapies available, gut, additional research needs carried out.

Language: Английский

Citations

15
Spray vaccination with a safe and bivalent H9N2 recombinant chimeric NDV vector vaccine elicits complete protection against NDV and H9N2 AIV challenge DOI Creative Commons
Xiaoquan Wang, Jing Dai, Wenhao Yang

et al.

Veterinary Research, Journal Year: 2025, Volume and Issue: 56(1)

Published: Jan. 31, 2025

Language: Английский

Citations

0
Cutting-edge progress in the protective efficacy of nanovaccines against poultry diseases DOI

Hassian León-Montoya,

Carlos Angulo

World s Poultry Science Journal, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 23

Published: Feb. 5, 2025

Language: Английский

Citations

0
Scutellaria baicalensis stem and leaf combat chicken-derived respiratory bacterial infection DOI
Xilin Wang, Sean M. Wu, Ning Guo

et al.

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: 202, P. 107439 - 107439

Published: Feb. 27, 2025

Language: Английский

Citations

0
Veterinarians’ perspectives on livestock diseases and antimicrobial use in Palestine DOI Creative Commons
Ibrahim Alzuheir

Veterinary World, Journal Year: 2025, Volume and Issue: unknown, P. 519 - 526

Published: Feb. 1, 2025

Background and Aim: The livestock sector is a crucial component of Palestine’s agricultural economy, supporting food security rural livelihoods. However, challenges such as infectious diseases, limited diagnostic resources, antimicrobial misuse impact animal health public safety. This study investigates veterinarians’ perspectives on disease prevalence use in Palestinian livestock, providing the first comprehensive analysis resistance (AMR) veterinary practice region. Materials Methods: A qualitative was conducted using focus groups comprising 93 veterinarians from West Bank, recruited through convenience snowball sampling. structured questionnaire collected data prescription patterns. Descriptive statistics Chi-square tests were used to assess associations between demographic characteristics practices. Results: Respiratory tract infections (RTIs) most frequently diagnosed (87.5%), followed by gastroenteritis (79.2%) mastitis (75.0%). Veterinarians predominantly prescribed broad-spectrum antimicrobials, including penicillins (50.5%), tetracyclines (48.4%), macrolides (46.2%). antimicrobials classified critically important for human medicine, quinolones (43.0%) third-generation cephalosporins (46.2%), notable. Some instances banned use, chloramphenicol, also reported. Conclusion: findings highlight reliance empirical treatments widespread human-critical raising concerns about AMR development. Improved stewardship, capabilities, regulatory frameworks are necessary mitigate these risks. Policies promoting culture sensitivity testing, along with targeted will enhance management safeguard Palestine. Keywords: resistance, Palestine, medicine.

Language: Английский

Citations

0
Chlorogenic acid mitigates avian pathogenic Escherichia coli-induced intestinal barrier damage in broiler chickens via anti-inflammatory and antioxidant effects DOI Creative Commons
Leyi Wei, Xiang Liu,

Zichao Tan

et al.

Poultry Science, Journal Year: 2025, Volume and Issue: 104(5), P. 105005 - 105005

Published: March 7, 2025

This study was conducted to investigate the protective effects of chlorogenic acid (CGA) on intestinal health in broilers challenged with avian pathogenic Escherichia coli (APEC). One hundred and eighty one-day-old male broiler chicks were divided into three groups six replicates ten each for a 21-day trial. The birds control APEC fed basal diet, while CGA-treated group received diet supplemented 1000 mg/kg CGA. At 14 days, CGA administered an suspension Compared group, incorporation decreased mortality cecal colonies bacterially (P < 0.05). Additionally, reduced relative weight heart, liver, kidney, gizzard, proventriculus, intestine, as well serum triglyceride level alanine aminotransferase activity APEC-challenged Supplementing concentrations interferon-γ, tumor necrosis factor-α, interleukin-1β, and/or interleukin-6 serum, duodenum, jejunum, ileum presumably through inactivation toll-like receptor 4/myeloid differentiation factor 88 pathway administration diamine oxidase d-lactate endotoxin concentrations, but increased ratio between villus height crypt depth duodenum jejunum APEC-infected chickens, accompanied by restored expression tight junction proteins (claudin-1, claudin-2, occludin, zonula occludens-1) genes involved apoptosis (B cell lymphoma-2 associated X protein, B lymphoma-2, cysteine-requiring aspartate protease 9) superoxide dismutase, glutathione peroxidase, catalase activities, levels mucosa, inhibited accumulation malondialdehyde possibly via activating nuclear factor-erythroid 2-related factor-2/heme oxygenase-1 results suggested that alleviated APEC-induced damage inhibiting inflammation oxidative stress. However, its potential application practical poultry production is contingent upon both efficacy cost-effectiveness.

Language: Английский

Citations

0
Comprehensive review of diagnostic concepts of major respiratory viruses (avian influenza virus, infectious bronchitis virus, Newcastle disease virus, infectious laryngotracheitis virus, and avian metapneumoviruses) in poultry DOI Open Access
Jongseo Mo

Korean Journal of Veterinary Research, Journal Year: 2025, Volume and Issue: 65(1), P. e5 - e5

Published: March 31, 2025

The rapid detection and differentiation of major respiratory viruses, such as avian influenza, infectious bronchitis virus, Newcastle disease laryngotracheitis metapneumoviruses within an infected poultry flock, are crucial for timely control measures. Effective management mandates identifying the etiologic agent differentiating between similar pathogens in early stages infection. traditional methods virus include isolation, neutralization, hemagglutination inhibition assays. Molecular-based methods, quantitative real-time polymerase chain reaction (PCR), have also become a standard. Future diagnostic concepts focus on advances point-of-care testing that can be applied directly on-site plants, biosensing lateral flow tests, which becoming prominent diagnostics. Portable PCR assays, loop-mediated isothermal amplification, popular. In addition, artificial intelligence, particularly those using deep-learning techniques, is increasingly being integrated into detection. This comprehensive review examines history methodologies supported these efforts decades discusses future trends field.

Language: Английский

Citations

0
First Report of Respiratory Infection Caused by Multidrug-Resistant Escherichia coli in an Ostrich in Romania DOI Creative Commons

Vlad Iorgoni,

Ionica Iancu,

Ionela Popa

et al.

Antibiotics, Journal Year: 2025, Volume and Issue: 14(4), P. 354 - 354

Published: March 31, 2025

Introduction: Ostrich farming is increasingly recognized for its economic potential but poses significant health challenges due to the risk of pathogen transmission, including multidrug-resistant Escherichia coli. Case study: This study reports a case four-month-old female ostrich from western Romania presenting with severe respiratory and digestive infections, progressing septicemia death. A post-mortem examination revealed extensive mucus in trachea, pulmonary congestion, hemorrhagic enteritis, approximately 1250 g metal objects ventriculus. Pure cultures E. coli were isolated lungs bone marrow identified via MALDI-TOF MS. The strain exhibited multidrug resistance several antibiotics, enrofloxacin, doxycycline, amoxicillin, highlighting critical issue antimicrobial veterinary medicine. Discussions: underscores need enhanced management practices mitigate environmental pathogenic risks, as well urgency developing alternative strategies controlling resistant bacterial infections avian species. Conclusions: highlights treatments stricter stewardship combat ostriches.

Language: Английский

Citations

0