Dioscin improves fatty liver hemorrhagic syndrome by promoting ERα-AMPK mediated mitophagy in laying hens DOI
Yuxiao Xing,

Benzeng Huang,

Ziyi Cui

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: 135, P. 156056 - 156056

Published: Sept. 19, 2024

Language: Английский

Arsenic trioxide induces innate immune response and inflammatory response in chicken liver via cGAS-STING/NF-κB pathway DOI
Hang Pan,

Limeng Zhou,

Junbo Zou

et al.

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2024, Volume and Issue: 286, P. 110017 - 110017

Published: Aug. 30, 2024

Language: Английский

Citations

1
The role of Drp1 – Pink1 – Parkin – mediated mitophagy in perfluorobutane sulfonate– induced hepatocyte damage DOI Creative Commons
Feng Yuan,

Yongheng Huang,

Bin Lü

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 285, P. 117066 - 117066

Published: Sept. 20, 2024

Language: Английский

Citations

1
Solid state fermentation of Diaphragma juglandis fructus with Aspergillus niger alleviates hydrogen peroxide-induced oxidative stress in HepG2 cells via Nrf2 signaling pathway DOI Creative Commons

Xingru Zao,

Nuo Chen,

Y. Li

et al.

Journal of Functional Foods, Journal Year: 2024, Volume and Issue: 116, P. 106209 - 106209

Published: April 27, 2024

Language: Английский

Citations

0
FOXO3 Activates MFN2 Expression to Maintain the Autophagy Response in Cancer Cells Under Amino Acid Deprivation DOI Open Access
Xu Jiang, Jing Wang, Fang Ma

et al.

Journal of Cellular Biochemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 22, 2024

The lack of amino acids triggers the autophagic response. Some studies have shown such starvation conditions also induce mitochondrial fusion, revealing a close correlation between two processes. Although Mitofusin-2 (MFN2) has been demonstrated to play role in fusion regulation, its response and variables that activate MFN2 under stress remain unknown. In this investigation, we screened confirmed forkhead box protein O3 (FOXO3) participates MFN2's expression during short periods starvation. Luciferase reporter test proved FOXO3 facilitates transcription by binding promoter region, downregulation directly depresses expression. Consequently, inhibiting FOXO3-MFN2 axis results loss disrupting normal morphology mitochondria, impairing degradation substrates, reducing autophagosome accumulation, ultimately leading blockage autophagy. conclusion, our work demonstrates pathway is essential for adaptive changes cellular autophagy nutritional constraints.

Language: Английский

Citations

0
Dioscin improves fatty liver hemorrhagic syndrome by promoting ERα-AMPK mediated mitophagy in laying hens DOI
Yuxiao Xing,

Benzeng Huang,

Ziyi Cui

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: 135, P. 156056 - 156056

Published: Sept. 19, 2024

Language: Английский

Citations

0