
Frontiers in Genetics, Journal Year: 2024, Volume and Issue: 15
Published: July 29, 2024
Tibial dyschondroplasia (TD) is a severe bone disease that affects fast-growing broiler chickens and causes economic loss. Despite previous studies, the regulatory mechanism of TD remains unclear thought to be primarily based on thiram induction, which may differ from naturally occurring diseases. To better understand TD, digital X-ray machine was used in present study determine its incidence four hundred yellow-feathered chickens. The results showed 22% after 6 weeks gradually decreased 8 10 weeks. body weight broilers with significantly compared NTD broilers. In addition, length density tibia were reduced eight weeks, This also examined tibial quality parameters (n = 12) found mineral content, density, ash calcium phosphorus content Transcriptome analysis revealed 849 differentially expressed genes (DEGs) growth plate between 6) groups 6). These enriched ECM-receptor interaction, cytokine-cytokine receptor signaling pathway, TGF-β signaling. Genes encoding alpha chain type XII collagen, is,
Language: Английский