The Global Challenge of Campylobacter: Antimicrobial Resistance and Emerging Intervention Strategies DOI Creative Commons

Zubeiru Bukari,

T. Emmanuel,

J.D. Woodward

et al.

Tropical Medicine and Infectious Disease, Journal Year: 2025, Volume and Issue: 10(1), P. 25 - 25

Published: Jan. 16, 2025

Antimicrobial resistance (AMR) in Campylobacter species, particularly C. jejuni and coli, poses a significant public health threat. These bacteria, which are commonly found livestock, poultry, companion animals, wildlife, the leading causes of foodborne illnesses, often transmitted through contaminated poultry. Extensive exposure to antibiotics human veterinary medicine creates selection pressure, driving mechanisms such as point mutations, horizontal gene transfer, efflux pumps. Resistance fluoroquinolones, macrolides, tetracyclines complicates treatment increases risk severe infections. Drug-resistant is humans via food, water, direct contact with highlighting its zoonotic potential. Addressing this challenge requires effective interventions. Pre-harvest strategies like biosecurity immune-based methods reduce bacterial loads on farms, while post-harvest measures, including carcass decontamination freezing, limit contamination. Emerging approaches, bacteriocins natural antimicrobials, offer chemical-free alternatives. Integrated, multidisciplinary interventions across food chain essential mitigate AMR transmission enhance safety. Sustainable agricultural practices, antimicrobial stewardship, innovative solutions critical curbing protecting global health. Our review examines dynamics presents current Campylobacter-related AMR, offering valuable insights for control poultry industry.

Language: Английский

The Global Challenge of Campylobacter: Antimicrobial Resistance and Emerging Intervention Strategies DOI Creative Commons

Zubeiru Bukari,

T. Emmanuel,

J.D. Woodward

et al.

Tropical Medicine and Infectious Disease, Journal Year: 2025, Volume and Issue: 10(1), P. 25 - 25

Published: Jan. 16, 2025

Antimicrobial resistance (AMR) in Campylobacter species, particularly C. jejuni and coli, poses a significant public health threat. These bacteria, which are commonly found livestock, poultry, companion animals, wildlife, the leading causes of foodborne illnesses, often transmitted through contaminated poultry. Extensive exposure to antibiotics human veterinary medicine creates selection pressure, driving mechanisms such as point mutations, horizontal gene transfer, efflux pumps. Resistance fluoroquinolones, macrolides, tetracyclines complicates treatment increases risk severe infections. Drug-resistant is humans via food, water, direct contact with highlighting its zoonotic potential. Addressing this challenge requires effective interventions. Pre-harvest strategies like biosecurity immune-based methods reduce bacterial loads on farms, while post-harvest measures, including carcass decontamination freezing, limit contamination. Emerging approaches, bacteriocins natural antimicrobials, offer chemical-free alternatives. Integrated, multidisciplinary interventions across food chain essential mitigate AMR transmission enhance safety. Sustainable agricultural practices, antimicrobial stewardship, innovative solutions critical curbing protecting global health. Our review examines dynamics presents current Campylobacter-related AMR, offering valuable insights for control poultry industry.

Language: Английский

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