COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis (Preprint) DOI Creative Commons

Tahani Al Rahbeni,

Prakasini Satapathy, Ramaiah Itumalla

et al.

Published: Nov. 21, 2023

BACKGROUND The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization. OBJECTIVE This umbrella review synthesizes findings from systematic reviews meta-analyses provide insights into perceptions on across diverse populations regions. METHODS We conducted a literature search major databases identify meta-analysis that reported hesitancy. AMSTAR-2 (A Measurement Tool Assess Systematic Reviews) criteria were used assess methodological quality included reviews. Meta-analysis was performed using STATA 17 with random effect model. data synthesis is presented in table format via narrative. RESULTS Our inclusion met by 78 published between 2021 2023. analysis revealed moderate rate 63% (95% CI 0.60%-0.67%) general population, significant heterogeneity (<i>I</i><sup>2</sup> = 97.59%). Higher rates observed among health care workers individuals chronic diseases, at 64% 0.57%-0.71%) 69% 0.61%-0.76%), respectively. However, lower noted pregnant women, 48% 0.42%-0.53%), parents consenting for their children, 61.29% 0.56%-0.67%). pooled 32% 0.25%-0.39%) population. assessment 19 high-quality, 38 moderate-quality, 15 low-quality, 6 critically low-quality meta-analyses. CONCLUSIONS presence globally, emphasizing necessity population-specific, culturally sensitive interventions clear, credible information dissemination foster acceptance. disparities accentuate need continuous research understand evolving address unique concerns needs populations, thereby aiding formulation effective inclusive strategies. CLINICALTRIAL PROSPERO CRD42023468363; https://tinyurl.com/2p9kv9cr

Language: Английский

COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis DOI Creative Commons

Tahani Al Rahbeni,

Prakasini Satapathy, Ramaiah Itumalla

et al.

JMIR Public Health and Surveillance, Journal Year: 2024, Volume and Issue: 10, P. e54769 - e54769

Published: April 30, 2024

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization.

Language: Английский

Citations

13
COVID-19 vaccine acceptance and its association with knowledge and attitude among patients with chronic diseases in Ethiopia DOI Creative Commons
Tilahun Degu Tsega, Abebaw Molla,

Tadesse Miretie Dessie

et al.

Human Vaccines & Immunotherapeutics, Journal Year: 2024, Volume and Issue: 20(1)

Published: May 17, 2024

COVID-19 vaccine acceptance is crucial for patients with chronic diseases, but previous studies in Ethiopia have yielded inconsistent and inconclusive findings. To fill this gap, we conducted a systematic review meta-analysis following established guidelines. Our search included relevant articles published between 2019 2023 from various sources. We assessed study heterogeneity publication bias, performed subgroup sensitivity analyses. findings indicate that the rate among diseases was 55.4%. also found good knowledge favorable attitude toward were positively associated rate. Based on these results, recommend healthcare professionals, policymakers, guide developers should work more to address relatively low Improving further about vaccines crucial. Future research include community-based qualitative enhance our understanding of acceptance.

Language: Английский

Citations

2
COVID-19 vaccine uptake and associated risk factors among first antenatal care attendees in Zambia, 2021-2022: a repeated cross-sectional study DOI Open Access
Tannia Tembo,

Paul Somwe,

Samuel Bosomprah

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 29, 2024

ABSTRACT Introduction Pregnant women are considered a high-risk group for COVID-19, and priority vaccination. Routine antenatal (ANC) care provides an opportunity to track trends factors associated with vaccine uptake. We sought evaluate COVID-19 uptake among pregnant attending ANC in Zambia. Methods conducted repeated cross-sectional study 39 public health facilities four districts Zambia from September 2021 2022. who were aged 15-49 years enrolled during their first visit. Every month, ∼20 per facility interviewed individual HIV testing counseling. estimated as the proportion of eligible participants self-reported having received vaccine. Results A total 9,203 screened, which 9,111 (99%) had vaccination status. Of included analysis, 1,818 (20%) period, trend increasing coverage time (0.5% 2020, 27% 2022). Conversely, 3,789 (42%) reported not being offered found that older age, education, employment status, prior infection significantly Conclusion was lower than estimates general population (27% across 2022), pointing missed opportunities protect this group. visits viable point conducting surveillance. Incorporating part routine package might increase Teaser key message Antenatal clinics could be easy sustainable platform women. Key Findings Despite evidence vaccines safe pregnancy, low through end Various demographic characteristics vaccines. Implications It is acceptable feasible assess hesitancy ANC. may provide easy, routinely monitoring other disease outbreaks. messages mass strategies can designed adopted reduce consequently, incorporated into help seeking services.

Language: Английский

Citations

1
COVID-19 vaccine uptake and associated risk factors among first antenatal care attendees in Zambia, 2021–2022: A repeated cross-sectional study DOI Creative Commons
Tannia Tembo,

Paul Somwe,

Samuel Bosomprah

et al.

PLOS Global Public Health, Journal Year: 2024, Volume and Issue: 4(10), P. e0003028 - e0003028

Published: Oct. 24, 2024

Pregnant women are considered a high-risk group for COVID-19, and priority vaccination. Routine antenatal care (ANC) provides an opportunity to track trends factors associated with vaccine uptake. We sought evaluate COVID-19 uptake among pregnant attending ANC assess the in Zambia. conducted repeated cross-sectional study 39 public health facilities four districts Zambia from September 2021 2022. who were aged 15-49 years enrolled during their first visit. Every month, ~20 per facility interviewed individual HIV counseling testing. estimated as proportion of eligible participants self-reported having received vaccine. A total 9,203 screened, which 9,111 (99%) had vaccination status. Of included analysis, 1,818 (20%) period, trend increasing coverage time (0.5% 2020, 27% 2022). Conversely, 3,789 (42%) reported not being offered found that 40-49 years, no education or attained some primary school education, employed, prior infection significantly was lower than estimates general population (27% across 2022), pointing missed opportunities protect this group. visits viable point conducting surveillance. Incorporating part routine package might increase

Language: Английский

Citations

1
COVID-19 Vaccine Uptake and Associated Factors among Healthcare Workers in Lower Juba Region of Jubaland State in Somalia DOI Open Access

Ahmednoor Shuriye Abdi,

Dominic Mogere,

Alexander Mbeke

et al.

International Journal of TROPICAL DISEASE & Health, Journal Year: 2024, Volume and Issue: 45(9), P. 1 - 9

Published: Aug. 28, 2024

Background: Somalia’s health systems were weakened by decades of conflicts, and this was made worse the coronavirus pandemic that hit nation like rest world. Despite existence different types COVID-19 vaccines, there has been a reluctance to take vaccine general population ironically healthcare workers. Objective: The purpose study evaluate uptake in Lower Juba Region Jubaland State Somalia among providers. Methods: research used quantitative descriptive design describe levels recruited 191 respondents. Stratified simple random sampling methods used. All significance tests conducted with two tails, threshold for statistical set at P less than 0.05. Results: From study, 46.6% respondents had vaccinated Covid-19 vaccine. Among group, 55.1% (49) received astrazeneca vaccine, 52.8% (47) 2 doses males up 51.5% (52). Regression analysis revealed observed differences covid age, gender, education work experience are not statistically significant. Trust protection vaccines (61.5%) influence from family friends (55.1%) rated as having highest on participants’ decision be against covid. Conclusion: research, close half vaccines. No significant have shown age groups, level vaccination status. Building trust encouraging family/friends support making easily accessible seen ways improve uptake.

Language: Английский

Citations

0
COVID-19 Vaccine Uptake and Factors Associated Among Pregnant Women in Mogadishu, Somalia DOI Creative Commons
Najib Isse Dirie, Maryan Abdullahi Sh. Nur, Abdirahman Khalif Mohamud

et al.

Infection and Drug Resistance, Journal Year: 2024, Volume and Issue: Volume 17, P. 3933 - 3943

Published: Sept. 1, 2024

Background: Pregnant women exhibit COVID-19 vaccine hesitancy due to concerns regarding potential risks their babies, doubts about efficacy, and limited access information.Therefore, this study aims estimate uptake factors associated with pregnant in Mogadishu, Somalia.Methods: A cross-sectional was conducted on using a questionnaire covering socio-demographic information, pregnancy-related characteristics, perceptions the vaccine, vaccination status.Univariable multivariable logistic regression analyses were utilized identify outcome variable.Results: Among 400 who participated study, 26.8% had received dose, only 14.9% receiving it during pregnancy.Reasons for not included lack of information (47.4%), its adverse effects personal health (33.8%), misconceptions impacts fertility or menstrual cycles (14.3%), belief vaccine's inefficacy (3.4%), fears fetus.In regression, history chronic diseases (AOR=3.27,95% CI=1.992-6.145),those perceived themselves at risk contracting (AOR=3.81,95% CI=2.11-5.10),those believed that accessible them (AOR=4.34,95% CI=2.915-6.165),and those discussed healthcare provider (AOR=3.91,95% CI=2.123-7.878)were more likely receive compared counterparts.Conclusion: Somalia, face challenges sub-optimal covid-19 uptake.Implementations should improve awareness facilitate discussions between providers women.In addition, efforts provide reliable alleviate effects, dispel fertility, cycles, foetal impact are crucial.

Language: Английский

Citations

0
COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis (Preprint) DOI Creative Commons

Tahani Al Rahbeni,

Prakasini Satapathy, Ramaiah Itumalla

et al.

Published: Nov. 21, 2023

BACKGROUND The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization. OBJECTIVE This umbrella review synthesizes findings from systematic reviews meta-analyses provide insights into perceptions on across diverse populations regions. METHODS We conducted a literature search major databases identify meta-analysis that reported hesitancy. AMSTAR-2 (A Measurement Tool Assess Systematic Reviews) criteria were used assess methodological quality included reviews. Meta-analysis was performed using STATA 17 with random effect model. data synthesis is presented in table format via narrative. RESULTS Our inclusion met by 78 published between 2021 2023. analysis revealed moderate rate 63% (95% CI 0.60%-0.67%) general population, significant heterogeneity (<i>I</i><sup>2</sup> = 97.59%). Higher rates observed among health care workers individuals chronic diseases, at 64% 0.57%-0.71%) 69% 0.61%-0.76%), respectively. However, lower noted pregnant women, 48% 0.42%-0.53%), parents consenting for their children, 61.29% 0.56%-0.67%). pooled 32% 0.25%-0.39%) population. assessment 19 high-quality, 38 moderate-quality, 15 low-quality, 6 critically low-quality meta-analyses. CONCLUSIONS presence globally, emphasizing necessity population-specific, culturally sensitive interventions clear, credible information dissemination foster acceptance. disparities accentuate need continuous research understand evolving address unique concerns needs populations, thereby aiding formulation effective inclusive strategies. CLINICALTRIAL PROSPERO CRD42023468363; https://tinyurl.com/2p9kv9cr

Language: Английский

Citations

0