Deleted Journal, Journal Year: 2024, Volume and Issue: 1(10), P. 480 - 482
Published: Oct. 1, 2024
Language: Английский
Deleted Journal, Journal Year: 2024, Volume and Issue: 1(3), P. 111 - 123
Published: March 1, 2024
In 2020, it was estimated that there were 155 million survivors of TB alive, all at risk possible post disability. The 2 nd International Post-Tuberculosis Symposium (Stellenbosch, South Africa) held to increase global awareness and empower TB-affected communities play an active role in driving the agenda. We aimed update knowledge on post-TB life illness, identify research priorities, build collaborations highlight need embed lung health outcomes clinical trials programmatic care services. symposium a multidisciplinary meeting included clinicians, researchers, survivors, funders policy makers. Ten academic working groups set their own goals covered following thematic areas: 1) patient engagement perspectives; 2) epidemiology modelling; 3) pathogenesis sequelae; 4) disease; 5) cardiovascular pulmonary vascular complications; 6) neuromuscular & skeletal 7) paediatric 8) economic-social psychological (ESP) consequences; 9) prevention, treatment management; 10) advocacy, stakeholder engagement. provided important updates for respective fields, highlighted made progress towards standardisation alignment definitions.
Language: Английский
Citations
12
European Respiratory Journal, Journal Year: 2023, Volume and Issue: 62(5), P. 2300925 - 2300925
Published: Oct. 12, 2023
Background Longitudinal cohort data of patients with tuberculosis (TB) and coronavirus disease 2019 (COVID-19) are lacking. In our global study, we describe long-term outcomes affected by TB COVID-19. Methods We collected from 174 centres in 31 countries on all COVID-19 between 1 March 2020 30 September 2022. Patients were followed-up until cure, death or end time. All had COVID-19; for analysis purposes, deaths attributed to TB, both. Survival was performed using Cox proportional risk-regression models, the log-rank test used compare survival mortality Results Overall, 788 (active sequelae) recruited countries, 10.8% (n=85) died during observation period. significantly lower among whose versus those dying because either alone (p<0.001). Significant adjusted risk factors higher age (hazard ratio (HR) 1.05, 95% CI 1.03–1.07), HIV infection (HR 2.29, 1.02–5.16) invasive ventilation 4.28, 2.34–7.83). For mortality, risks 1.03, 1.02–1.04), male sex 2.21, 1.24–3.91), oxygen requirement 7.93, 3.44–18.26) 2.19, 1.36–3.53). Conclusions cohort, outcome >10% A range demographic clinical predictors associated adverse outcomes.
Language: Английский
Citations
22
EClinicalMedicine, Journal Year: 2024, Volume and Issue: 70, P. 102511 - 102511
Published: Feb. 26, 2024
Tuberculosis (TB) remains a global public health challenge, causing substantial mortality and morbidity. While TB treatment has made significant progress, it often leaves survivors with post-TB sequelae, resulting in long-term issues. Current healthcare systems guidelines lack comprehensive strategies to address primarily due insufficient evidence. This systematic review meta-analysis aimed identify effective interventions for preventing sequelae.
Language: Английский
Citations
8
Lung India, Journal Year: 2024, Volume and Issue: 41(4), P. 307 - 317
Published: June 28, 2024
ABSTRACT Introduction: Pneumococcal diseases pose a significant public health concern in India, with substantial morbidity and mortality, the elderly those coexisting medical conditions being most at risk. Pneumococcus was also seen to be one of main reasons for co-infection, pneumonia complications COVID. Current guidelines recommend vaccination specific adult populations, but there is lack uniformity guidance on risk stratification, prioritisation optimal timing. Methods: Nation Against Infections – Expert Panel Opinion (NAP-EXPO) panel convened review update recommendations pneumococcal India. The 23 experts from various specialties engaged discussions evidence-based reviews, discussed appropriate age vaccination, stratification COPD asthma patients, strategies post-COVID smokers diabetics, as well methods improve vaccine awareness uptake. Outcome: NAP-EXPO recommends following adults: All healthy individuals 60 years above should receive vaccine; all regardless severity, high-risk cases lung fibrosis or damage, vaccinated current passive educated offered vaccine, their condition; diabetic irrespective diabetes control. Strategies uptake involve general practitioners (GPs), primary physicians (PHPs) treating patients high disease. Advocacy campaigns media, including social media platforms. Conclusion: These aim enhance coverage among populations India order ensure reduction burden diseases, era. There need create more evidence data support that will useful wider range suggested our consensus.
Language: Английский
Citations
3
Archivos de Bronconeumología, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Citations
0
Deleted Journal, Journal Year: 2025, Volume and Issue: 2(5), P. 248 - 250
Published: May 9, 2025
Although much attention is given to diagnosis and treatment for TB, recent evidence highlights the suffering that occurs after patients are ‘cured’. This issue of IJTLD Open includes two studies improve our understanding long-term impact TB. First, a study in Kenya, Uganda, Zambia Zimbabwe evaluated feasibility assessing referring TB comorbidities, risk factors disabilities within national programmes. Second, who successfully completed China sheds light on sequelae The combined findings reinforce need integrate care strategies into programmes address these health challenges.
Language: Английский
Citations
0
Jornal Brasileiro de Pneumologia, Journal Year: 2023, Volume and Issue: unknown, P. e20230269 - e20230269
Published: Nov. 28, 2023
Historically, all efforts against tuberculosis were focused on rapid diagnosis and effective treatment to break the chain of transmission Mycobacterium tuberculosis. However, in last few years, more evidence has been found dramatic consequences condition defined as post-tuberculosis lung disease (PTLD). Approximately one third patients surviving pulmonary face considerable ongoing morbidities, including respiratory impairment, psychosocial challenges, reduced health-related quality life after completion. Given important global local burden tuberculosis, well estimated PTLD, development a consensus document by Brazilian scientific society-Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)-was considered urgent for prevention management this order allocate resources within services appropriately serve guide health care professionals. A team eleven pulmonologists methodologist was created SBPT review current PTLD develop recommendations adapted context. The expert panel selected topics basis international guidelines. During first phase, three members drafted recommendations, which divided into sections: definition prevalence assessment PTLD. In second reviewed, discussed, revised until reached. formally approved special session organized during 2023 Annual Conference.
Language: Английский
Citations
9
The International Journal of Tuberculosis and Lung Disease, Journal Year: 2023, Volume and Issue: 27(10), P. 729 - 741
Published: Sept. 26, 2023
BACKGROUND: The aim of these clinical standards is to provide guidance on 'best practice' care for the diagnosis, treatment and prevention post-COVID-19 lung disease.METHODS: A panel international experts representing scientific societies, associations groups active in disease was identified; 45 completed a Delphi process. 5-point Likert scale indicated level agreement with draft standards. final version approved by consensus (with 100% agreement).RESULTS: Four were agreed patients previous history COVID-19: Standard 1, Patients sequelae not explained an alternative diagnosis should be evaluated possible disease; 2, function impairment, reduced exercise tolerance, quality life (QoL) or other relevant signs ongoing symptoms ≥4 weeks after onset first pulmonary rehabilitation (PR); 3, PR programme based feasibility, effectiveness cost-effectiveness criteria, organised according local health services tailored individual patient's needs; 4, Each patient undergoing completing determine its have access counselling/health education session.CONCLUSION: This consensus-based set disease. Our improve QoL guiding clinicians, managers public officers planning implementing manage
Language: Английский
Citations
7
Deleted Journal, Journal Year: 2024, Volume and Issue: 1(3), P. 136 - 143
Published: March 1, 2024
<sec><title>BACKGROUND</title>In Pakistan, 84% of healthcare is provided by the private sector. We conducted an epidemiological and programme review for TB to document progress guide further efforts.</sec><sec><title>METHODS</title>Surveillance data systems were assessed before analysing data. reviewed at federal, provincial peripheral levels compiled national along with WHO estimates describe evolution indicators.</sec><sec><title>RESULTS</title>In 2021, estimated number cases, 55% overall cases 18% drug-resistant diagnosed treated respectively. The contribution sector in case detection increased from 30% 2017 40% 2021. For newly pulmonary proportion confirmed was 52%. In testing rifampicin resistance among 66% new previously patients. treatment success rate exceeded 90% drug susceptible TB. main challenges identified a funding gap (60% 2021–2023), fragmented electronic collection suboptimal coordination provinces.</sec><sec><title>CONCLUSIONS</title>The prevent controlling By addressing these, Pakistan could improve coverage interventions, including diagnosis treatment. Bacteriological confirmation using recommended diagnostics also requires optimisation.</sec>
Language: Английский
Citations
1
Indian Journal of Immunology and Respiratory Medicine, Journal Year: 2024, Volume and Issue: 9(1), P. 1 - 2
Published: April 15, 2024
Post-tuberculosis lung disease (PTLD) presents a significant challenge in the management of tuberculosis patients, with far-reaching implications for global health. This editorial explores multifaceted nature PTLD, encompassing its pathophysiology, clinical manifestations, diagnostic complexities, and public PTLD arises from pulmonary damage due to an active infection, leading inflammation, scarring, fibrosis within lungs. Clinical manifestations vary widely, ranging chronic respiratory symptoms severe failure, often resembling obstructive or restrictive disease. The diagnosis is hindered by heterogeneous presentation overlap other conditions, necessitating comprehensive evaluation through function tests radiological imaging. imposes substantial burden on health systems, particularly regions high prevalence, contributing increased morbidity mortality rates. Management strategies focus alleviating symptoms, preserving function, preventing progression pharmacological interventions, rehabilitation, and, select cases, surgical interventions. Preventive measures include effective control measures, vaccination against pathogens, addressing social determinants Overall, understanding essential improving patient outcomes reducing burden, highlighting importance concerted efforts raise awareness, enhance capabilities, develop this complex condition.
Language: Английский
Citations
1