Synthesis and Evaluation of Physicochemical Properties of a Solid Lipid Nanocarrier Containing a Sulfonamide Derivative and Investigation of Its Effect on Breast Cancer Cells DOI

Tahereh Rahdari,

Hossein Ghafouri, S. Mohsen Asghari

et al.

Cell and Tissue Journal, Journal Year: 2024, Volume and Issue: 15(4), P. 299 - 316

Published: Dec. 21, 2024

Language: Английский

Adenocarpine, Marmesin, and Lycocernuine from Ficus benjamina as Promising Inhibitors of Aldose Reductase in Diabetes: A Bioinformatics-Guided Approach DOI
M. Oliur Rahman, Sheikh Sunzid Ahmed,

Ali S. Alqahtani

et al.

Applied Biochemistry and Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Language: Английский

Citations

0
Anti-inflammatory activity and molecular docking study of pyranopyrazole derivatives synthesized using basic ionic liquid DOI

Satish S. Kadam,

D. S. Gaikwad,

Pravin R. Kharade

et al.

Journal of the Iranian Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: March 29, 2025

Language: Английский

Citations

0
Novel 2,4-Dichloro-5-sulfamoylbenzoic Acid Oxime Esters: First Studies as Potential Human Carbonic Anhydrase Inhibitors DOI
Jaydeo T. Kilbile, Suryakant B. Sapkal, Gioele Renzi

et al.

ACS Medicinal Chemistry Letters, Journal Year: 2024, Volume and Issue: 15(6), P. 972 - 978

Published: May 23, 2024

In this study, a focused library of oxime ester derivatives 2,4-dichloro-5-sulfamoylbenzoic acid (lasamide) containing Schiff bases was synthesized and tested in vitro for their ability to inhibit the cytosolic human carbonic anhydrases (hCAs) I II, as well transmembrane tumor-associated IX XII isoforms. As result, we obtained first line knowledge on lasamide potentially useful development CA inhibitors (CAIs). particular, our attention derivative 11, which selective toward hCAs over isoenzymes. An silico study conducted assess binding mode 11 within XII. Also, antiproliferative assays highlighted promising derivatives. The data are currently use better-performing compounds

Language: Английский

Citations

2
Assessing [DMAP-DABCO]AcO as an effective dual basic ionic liquid for the synthesis of Chromeno[2,3-d]pyrimidine derivatives and Exploring their Anti-Cancer activity through computational analysis DOI
Pravin R. Kharade,

D. S. Gaikwad,

Sanket Rathod

et al.

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: 416, P. 126484 - 126484

Published: Nov. 12, 2024

Language: Английский

Citations

1
Design, Synthesis, Biological and Computational Analysis of Isatin-based bis-Thiourea Analogues as Anti-diabetic and Anti-nematode Agents DOI
Muhammad Nadeem,

Shawkat Hayat,

Mustafa Zeyadi

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1323, P. 140698 - 140698

Published: Nov. 12, 2024

Language: Английский

Citations

1
Synthesis and Evaluation of Physicochemical Properties of a Solid Lipid Nanocarrier Containing a Sulfonamide Derivative and Investigation of Its Effect on Breast Cancer Cells DOI

Tahereh Rahdari,

Hossein Ghafouri, S. Mohsen Asghari

et al.

Cell and Tissue Journal, Journal Year: 2024, Volume and Issue: 15(4), P. 299 - 316

Published: Dec. 21, 2024

Language: Английский

Citations

0