Genes involved in chronic wound healing and their therapeutic potential DOI Open Access
Barani Karikalan, Srikumar Chakravarthi

IP Archives of Cytology and Histopathology Research, Journal Year: 2023, Volume and Issue: 8(2), P. 83 - 89

Published: July 15, 2023

Chronic wounds are that fail to progress through the normal stages of healing and remain open for an extended period time. These often require specialized treatment approaches. While genes involved in wound play important roles chronic as well, specific genetic factors contributing still being studied. Some have been implicated their potential include Transforming Growth Factor-Beta (TGF-β) Family, Matrix Metalloproteinases (MMPs), Factor-Alpha (TGF-α), Hypoxia-Inducible Factor-1 (HIF-1), Vascular Endothelial Factor (VEGF), Nitric Oxide Synthase (NOS) Wound-Healing-Associated microRNAs. It's note multifactorial, requires a comprehensive approach addressing various beyond alone. Other aspects such underlying medical conditions, infection, local environment, patient-specific also crucial management.

Language: Английский

Proteomics analysis revealed the therapeutic role of adipose-derived mesenchymal stem cells on radiation-induced colorectal fibrosis in rats DOI Open Access

Mya Thandar,

Leisheng Zhang, Xiaojie Yang

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2024, Volume and Issue: 182, P. 117763 - 117763

Published: Dec. 17, 2024

Language: Английский

Citations

0
Design, synthesis and evaluation of novel UDCA-aminopyrimidine hybrids as ATX inhibitors for the treatment of hepatic and pulmonary fibrosis DOI
Yue Hu, Lingyu Li, Yu Tian

et al.

European Journal of Medicinal Chemistry, Journal Year: 2023, Volume and Issue: 264, P. 116029 - 116029

Published: Dec. 8, 2023

Language: Английский

Citations

1
Genes involved in chronic wound healing and their therapeutic potential DOI Open Access
Barani Karikalan, Srikumar Chakravarthi

IP Archives of Cytology and Histopathology Research, Journal Year: 2023, Volume and Issue: 8(2), P. 83 - 89

Published: July 15, 2023

Chronic wounds are that fail to progress through the normal stages of healing and remain open for an extended period time. These often require specialized treatment approaches. While genes involved in wound play important roles chronic as well, specific genetic factors contributing still being studied. Some have been implicated their potential include Transforming Growth Factor-Beta (TGF-β) Family, Matrix Metalloproteinases (MMPs), Factor-Alpha (TGF-α), Hypoxia-Inducible Factor-1 (HIF-1), Vascular Endothelial Factor (VEGF), Nitric Oxide Synthase (NOS) Wound-Healing-Associated microRNAs. It's note multifactorial, requires a comprehensive approach addressing various beyond alone. Other aspects such underlying medical conditions, infection, local environment, patient-specific also crucial management.

Language: Английский

Citations

0