Oxidative Stress in Maternal and Offspring Kidney Disease and Hypertension: A Life-Course Perspective

Antioxidants, Journal Year: 2025, Volume and Issue: 14(4), P. 387 - 387

Published: March 26, 2025

Kidney disease and hypertension are interconnected, prevalent conditions that affect both pregnant women children. Oxidative stress occurs when reactive oxygen species or nitrogen exceed the capacity of antioxidant systems. It plays a critical role in kidney development, resulting programming increased risks for across life course. Animal models have significantly advanced our understanding oxidative stress-related programming, molecular mechanisms involved, early-life interventions to prevent disease. This review critically examines influence perinatal on highlighting its long-term effects outcomes susceptibility hypertension. also explores potential antioxidant-based preventing Furthermore, addresses existing gap between insights gained from animal their translation into clinical practices, emphasizing challenges opportunities future research this area.

Language: Английский

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Redox modulatory role of DJ-1 in Parkinson’s disease

Biogerontology, Journal Year: 2025, Volume and Issue: 26(2)

Published: March 30, 2025

Language: Английский

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Hesperidin mitigated deoxynivalenol-induced liver injury by inhibiting ROS/ P53/ PGC-1α-mediated disruption of mitochondrial dynamics and PANoptosis

Phytomedicine, Journal Year: 2025, Volume and Issue: unknown, P. 156747 - 156747

Published: April 1, 2025

Language: Английский

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Revolutionizing Oral Care: Reactive Oxygen Species (ROS)-Regulating Biomaterials for Combating Infection and Inflammation

Redox Biology, Journal Year: 2024, Volume and Issue: 79, P. 103451 - 103451

Published: Nov. 30, 2024

Language: Английский

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