Sustainable Electrochemical-Magnetic Biosensor Fabricated from Recycled Materials for Label-Free Detection of SARS-CoV-2 in Human Saliva

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: March 14, 2025

The COVID-19 pandemic has highlighted the critical need for scalable, rapid, and cost-effective diagnostic solutions, especially in resource-limited settings. In this study, we developed a sustainable magnetic electrochemical biosensor mass testing of SARS-CoV-2, emphasizing affordability, environmental impact reduction, clinical applicability. By leveraging recycled materials from spent batteries plastics, achieved circular economy-based fabrication process with recyclability rate 98.5%. employs MnFe2O4 nanoparticles functionalized anti-SARS-CoV-2 antibodies, integrated into 3D-printed device decentralized testing. Advanced characterization confirmed biosensor's robust performance, including high sensitivity (LOD: 3.46 pg mL–1) specificity, results demonstrating 95% correlation to RT-PCR gold standard cost used per test is only USD 0.2, making it highly affordable suitable large-scale production using additive manufacturing. Key features include simple preparation, rapid response, reusability, ideal point-of-care diagnostics. Beyond COVID-19, platform's modularity allows adaptation other viral diseases, offering versatile solution global challenges. This work highlights potential integrating sensing practices address healthcare inequities reduce impact.

Language: Английский

Network properties of the global waste trade

Environmental and Sustainability Indicators, Journal Year: 2024, Volume and Issue: unknown, P. 100550 - 100550

Published: Dec. 1, 2024

Language: Английский