Clinical outcomes of persistent cough following coronavirus disease 2019 infection: a 1-year retrospective cohort study
Asia Pacific Allergy,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 20, 2025
Background:
Cough
is
one
of
the
multiple
prolonged
symptoms
observed
in
patients
who
had
coronavirus
disease
2019
(COVID-19)
infection.
Objective:
We
assessed
clinical
outcomes
and
identified
factors
contributing
to
cough
persistence
post-COVID-19.
Methods:
This
retrospective
cohort
study
included
adults
visited
a
specialist
clinic
between
2022
2023.
All
participants
underwent
systematic
investigation
treatment
for
persistent
cough.
was
at
2-
12-month
follow-ups.
Participants
were
classified
as
having
if
they
current
troublesome
follow-ups,
severity
visual
analog
scale
(VAS)
score
change
below
30.
Results:
Sixty-six
(mean
age
48.7
years;
72.7%
women)
analyzed
divided
into
2
groups:
(33.3%)
remitted
(66.7%).
The
group
significantly
higher
prevalence
abnormal
laryngeal
sensation,
sputum
production,
breathing
difficulty,
airway
eosinophilia;
their
VAS
changes
months
also
lower.
Multivariate
analyses
indicated
associations
1
year
such
eosinophilia
(adjusted
odds
ratio
[aOR],
6.78),
sensation
(aOR,
6.42),
low
reduction
1.05).
Conclusion:
Persistent
remained
significant
issue
one-third
after
COVID-19.
features
commonly
chronic
present
those
have
experienced
COVID-19,
which
contributed
These
findings
underscore
need
assessment
tailored
strategies
effectively
manage
Language: Английский
Characterization and clinical outcomes of outpatients with subacute or chronic post COVID-19 cough: a real-world study
PeerJ,
Journal Year:
2024,
Volume and Issue:
12, P. e18705 - e18705
Published: Dec. 11, 2024
Background
Limited
research
exists
on
the
features
and
management
of
post-COVID
cough.
This
real-world
study
investigates
outpatients
with
subacute
or
chronic
cough,
aiming
to
delineate
characteristics
regimen
responses
within
population.
Method
We
enrolled
eligible
patients
from
our
outpatient
unit
between
August
2023
February
2024.
Comprehensive
clinical
data,
prescriptions,
patient-reported
cough
severity
were
collected
during
primary
visit
subsequent
follow-ups.
Result
A
total
141
patients,
aged:
42
±
14
years
old,
included,
70%
being
female.
The
median
duration
was
8
weeks
(interquartile
range
4–12
weeks).
Sixty
percent
presented
a
dry
while
rest
had
coughs
phlegm.
Over
half
reported
abnormal
laryngeal
sensations
(54%).
Twenty-one
coughed
day,
32%
constantly,
48%
experienced
nocturnal
episodes.
Compound
methoxyphenamine
capsules
most
prescribed,
but
found
ICS/LABA
be
effective,
followed
by
compound
capsules,
montelukast,
Chinese
patent
drugs.
Conclusion
Females
exhibit
higher
prevalence
recommends
as
preferred
treatment.
These
findings
warrant
validation
through
larger,
prospectively
designed
studies.
Language: Английский